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  • Top cofit genes for Rv2829c from Mycobacterium tuberculosis H37Rv

    Possible toxin VapC22
    SEED: VapC22 antibacterial toxin protein

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv1702c Conserved hypothetical protein no 0.32
    2 Rv0858c Probable N-succinyldiaminopimelate aminotransferase DapC (DAP-at) no 0.32
    3 Rv0947c Probable mycolyl transferase, pseudogene no 0.31
    4 Rv1524 Probable glycosyltransferase no 0.31
    5 Rv1191 Conserved protein no 0.30
    6 Rv3107c Possible alkyldihydroxyacetonephosphate synthase AgpS (alkyl-DHAP synthase) (alkylglycerone-phosphate synthase) no 0.30
    7 Rv3543c Probable acyl-CoA dehydrogenase FadE29 no 0.27
    8 Rv3431c Possible transposase (fragment) no 0.27
    9 Rv0233 Ribonucleoside-diphosphate reductase (beta chain) NrdB (ribonucleotide reductase small chain) no 0.27
    10 Rv1222 Anti-sigma factor RseA no 0.27
    11 Rv1109c Conserved protein no 0.27
    12 Rv0855 Probable fatty-acid-CoA racemase Far no 0.27
    13 Rv3585 DNA repair protein RadA (DNA repair protein SMS) no 0.26
    14 Rv2616 Conserved protein no 0.26
    15 Rv0648 Alpha-mannosidase no 0.26
    16 Rv1182 Probable conserved polyketide synthase associated protein PapA3 no 0.26
    17 Rv1515c Conserved hypothetical protein no 0.25
    18 Rv1677 Probable conserved lipoprotein DsbF no 0.25
    19 Rv0502 Conserved protein no 0.25
    20 Rv3774 Possible enoyl-CoA hydratase EchA21 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) 0.45 0.25

    Or look for negative cofitness