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  • Top cofit genes for Rv2435c from Mycobacterium tuberculosis H37Rv

    Probable cyclase (adenylyl-or guanylyl-)(adenylate-or guanylate-)
    SEED: Adenylate cyclase (EC 4.6.1.1)
    KEGG: putative cyclase

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv0587 Conserved hypothetical integral membrane protein YrbE2A no 0.29
    2 Rv0773c Probable bifunctional acylase GgtA: cephalosporin acylase (GL-7ACA acylase) + gamma-glutamyltranspeptidase (GGT) no 0.28
    3 Rv0474 Probable transcriptional regulatory protein no 0.28
    4 Rv2891 Conserved hypothetical protein no 0.27
    5 Rv2417c Conserved protein no 0.26
    6 Rv2713 Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleotide transhydrogenase) no 0.25
    7 Rv0610c Hypothetical protein no 0.24
    8 Rv1869c Probable reductase no 0.24
    9 Rv0426c Possible transmembrane protein no 0.23
    10 Rv2032 Conserved protein Acg no 0.23
    11 Rv0961 Probable integral membrane protein no 0.23
    12 Rv2948c P-hydroxybenzoyl-AMP ligase FadD22 no 0.23
    13 Rv2990c Hypothetical protein no 0.23
    14 Rv0918 Conserved protein no 0.23
    15 Rv2819c Hypothetical protein no 0.22
    16 Rv0594 Mce-family protein Mce2F no 0.22
    17 Rv2294 Probable aminotransferase no 0.22
    18 Rv0968 Conserved protein no 0.22
    19 Rv0100 Conserved hypothetical protein no 0.21
    20 Rv3743c Probable cation transporter P-type ATPase CtpJ no 0.21

    Or look for negative cofitness