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Cofit
Protein
Homologs
Top cofit genes for Rv2431c from
Mycobacterium tuberculosis H37Rv
PE family protein PE25
SEED: PE family protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv2404c
Probable GTP-binding protein LepA (GTP-binding elongation factor)
no
0.45
2
Rv0877
Conserved hypothetical protein
no
0.40
3
Rv2388c
Probable oxygen-independent coproporphyrinogen III oxidase HemN (coproporphyrinogenase) (coprogen oxidase)
no
0.35
4
Rv1748
Unknown protein
no
0.28
5
Rv1625c
Membrane-anchored adenylyl cyclase Cya (ATP pyrophosphate-lyase) (adenylate cyclase)
no
0.28
6
Rv3220c
Probable two component sensor kinase
no
0.27
7
Rv0056
50S ribosomal protein L9 RplI
no
0.27
8
Rv1681
Possible molybdopterin biosynthesis protein MoeX
no
0.27
9
Rv0234c
Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1
no
0.26
10
Rv1375
Conserved hypothetical protein
no
0.26
11
Rv2583c
Probable GTP pyrophosphokinase RelA (ATP:GTP 3'-pyrophosphotransferase) (PPGPP synthetase I) ((P)PPGPP synthetase) (GTP diphosphokinase)
no
0.26
12
Rv3870
ESX conserved component EccCa1. ESX-1 type VII secretion system protein. Possible transmembrane protein.
no
0.25
13
Rv1925
Probable acyl-CoA ligase FadD31 (acyl-CoA synthetase) (acyl-CoA synthase)
no
0.25
14
Rv2752c
Conserved hypothetical protein
no
0.24
15
Rv1626
Probable two-component system transcriptional regulator
no
0.24
16
Rv0743c
Hypothetical protein
no
0.24
17
Rv1957
Hypothetical protein
no
0.24
18
Rv1771
L-gulono-1,4-lactone dehydrogenase
no
0.24
19
Rv1908c
Catalase-peroxidase-peroxynitritase T KatG
no
0.24
20
Rv2332
Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarboxylating)) (pyruvic-malic carboxylase) (NAD-me)
no
0.24
Or look for
negative cofitness