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Cofit
Protein
Homologs
Top cofit genes for Rv2223c from
Mycobacterium tuberculosis H37Rv
Probable exported protease
SEED: Putative hydrolase
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv3395c
Conserved hypothetical protein
no
0.34
2
Rv1132
Conserved membrane protein
no
0.33
3
Rv1741
Possible toxin VapC34. Contains PIN domain.
no
0.31
4
Rv2588c
Probable conserved membrane protein secretion factor YajC
no
0.30
5
Rv3847
Hypothetical protein
no
0.29
6
Rv2787
Conserved hypothetical alanine rich protein
no
0.28
7
Rv3561
Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.28
8
Rv1681
Possible molybdopterin biosynthesis protein MoeX
no
0.27
9
Rv0628c
Conserved hypothetical protein
no
0.27
10
Rv3437
Possible conserved transmembrane protein
no
0.26
11
Rv2590
Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.26
12
Rv3567c
Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase.
no
0.26
13
Rv2994
Probable conserved integral membrane protein
no
0.25
14
Rv1948c
Hypothetical protein
no
0.25
15
Rv1225c
Conserved hypothetical protein
no
0.24
16
Rv3179
Conserved protein
no
0.23
17
Rv0332
Conserved protein
no
0.23
18
Rv0659c
Toxin MazF2
no
0.23
19
Rv3033
Unknown protein
no
0.23
20
Rv0766c
Probable cytochrome P450 123 Cyp123
no
0.22
Or look for
negative cofitness