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  • Top cofit genes for Rv2223c from Mycobacterium tuberculosis H37Rv

    Probable exported protease
    SEED: Putative hydrolase

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv3395c Conserved hypothetical protein no 0.34
    2 Rv1132 Conserved membrane protein no 0.33
    3 Rv1741 Possible toxin VapC34. Contains PIN domain. no 0.31
    4 Rv2588c Probable conserved membrane protein secretion factor YajC no 0.30
    5 Rv3847 Hypothetical protein no 0.29
    6 Rv2787 Conserved hypothetical alanine rich protein no 0.28
    7 Rv3561 Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) no 0.28
    8 Rv1681 Possible molybdopterin biosynthesis protein MoeX no 0.27
    9 Rv0628c Conserved hypothetical protein no 0.27
    10 Rv3437 Possible conserved transmembrane protein no 0.26
    11 Rv2590 Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) no 0.26
    12 Rv3567c Possible oxidoreductase. Possible 3-hydroxy-9,10-seconandrost-1,3,5(10)-triene-9,17-dione hydroxylase. no 0.26
    13 Rv2994 Probable conserved integral membrane protein no 0.25
    14 Rv1948c Hypothetical protein no 0.25
    15 Rv1225c Conserved hypothetical protein no 0.24
    16 Rv3179 Conserved protein no 0.23
    17 Rv0332 Conserved protein no 0.23
    18 Rv0659c Toxin MazF2 no 0.23
    19 Rv3033 Unknown protein no 0.23
    20 Rv0766c Probable cytochrome P450 123 Cyp123 no 0.22

    Or look for negative cofitness