Top cofit genes for Rv2048c from Mycobacterium tuberculosis H37Rv

Polyketide synthase Pks12
SEED: Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

Rank Hit Name Description Conserved? Cofitness  
1 Rv2047c Conserved hypothetical protein no 0.92
2 Rv0202c Probable conserved transmembrane transport protein MmpL11 no 0.89
3 Rv0676c Probable conserved transmembrane transport protein MmpL5 no 0.63
4 Rv1127c Probable pyruvate, phosphate dikinase PpdK no 0.60
5 Rv0643c Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase) no 0.58
6 Rv1589 Probable biotin synthetase BioB no 0.55
7 Rv1568 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA no 0.54
8 Rv3066 Probable transcriptional regulatory protein (probably DeoR-family) no 0.54
9 Rv3229c Possible linoleoyl-CoA desaturase (delta(6)-desaturase) no 0.52
10 Rv3230c Hypothetical oxidoreductase no 0.51
11 Rv0677c Possible conserved membrane protein MmpS5 no 0.49
12 Rv1273c Probable drugs-transport transmembrane ATP-binding protein ABC transporter no 0.49
13 Rv2497c Probable branched-chain keto acid dehydrogenase E1 component, alpha subunit BkdA no 0.49
14 Rv1590 Conserved hypothetical protein no 0.49
15 Rv0642c Methoxy mycolic acid synthase 4 MmaA4 (methyl mycolic acid synthase 4) (MMA4) (hydroxy mycolic acid synthase) no 0.49
16 Rv2606c Possible pyridoxine biosynthesis protein SnzP no 0.48
17 Rv1272c Probable drugs-transport transmembrane ATP-binding protein ABC transporter no 0.48
18 Rv1569 Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase) no 0.48
19 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) no 0.46
20 Rv2476c Probable NAD-dependent glutamate dehydrogenase Gdh (NAD-Gdh) (NAD-dependent glutamic dehydrogenase) no 0.43

Or look for negative cofitness