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  • Top cofit genes for Rv2021c from Mycobacterium tuberculosis H37Rv

    Transcriptional regulatory protein
    SEED: Transcriptional regulator, XRE family

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv2404c Probable GTP-binding protein LepA (GTP-binding elongation factor) no 0.31
    2 Rv2887 Probable transcriptional regulatory protein no 0.29
    3 Rv3730c Conserved hypothetical protein no 0.27
    4 Rv1959c Possible toxin ParE1 no 0.26
    5 Rv3894c ESX conserved component EccC2. ESX-2 type VII secretion system protein. Possible membrane protein. no 0.26
    6 Rv0917 Possible glycine betaine transport integral membrane protein BetP no 0.24
    7 Rv0978c PE-PGRS family protein PE_PGRS17 no 0.24
    8 Rv0592 Mce-family protein Mce2D no 0.24
    9 Rv3690 Probable conserved membrane protein no 0.24
    10 Rv1956 Possible antitoxin HigA no 0.23
    11 Rv2485c Probable carboxylesterase LipQ no 0.22
    12 Rv2291 Probable thiosulfate sulfurtransferase SseB no 0.22
    13 Rv3739c PPE family protein PPE67 no 0.22
    14 Rv3578 Possible arsenical pump integral membrane protein ArsB2 no 0.22
    15 Rv0737 Possible transcriptional regulatory protein no 0.22
    16 Rv1238 Probable sugar-transport ATP-binding protein ABC transporter SugC no 0.21
    17 Rv0092 Cation transporter P-type ATPase a CtpA no 0.21
    18 Rv1682 Probable coiled-coil structural protein no 0.20
    19 Rv2586c Probable protein-export membrane protein SecF no 0.20
    20 Rv1900c Probable lignin peroxidase LipJ no 0.20

    Or look for negative cofitness