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  • Top cofit genes for Rv2004c from Mycobacterium tuberculosis H37Rv

    Conserved protein

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv3374 Probable enoyl-CoA hydratase (fragment) EchA18.1 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase) no 0.28
    2 Rv3446c Hypothetical alanine and valine rich protein no 0.27
    3 Rv0404 Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) no 0.25
    4 Rv2205c Conserved hypothetical protein no 0.25
    5 Rv0518 Possible exported protein no 0.25
    6 Rv0981 Mycobacterial persistence regulator MRPA (two component response transcriptional regulatory protein) no 0.25
    7 Rv0188 Probable conserved transmembrane protein no 0.24
    8 Rv2948c P-hydroxybenzoyl-AMP ligase FadD22 no 0.23
    9 Rv0036c Conserved protein no 0.23
    10 Rv0293c Conserved protein no 0.23
    11 Rv1902c Probable sialic acid-transport integral membrane protein NanT no 0.22
    12 Rv3437 Possible conserved transmembrane protein no 0.22
    13 Rv1761c Possible exported protein no 0.21
    14 Rv2208 Probable cobalamin 5'-phosphate synthase CobS no 0.21
    15 Rv2777c Conserved hypothetical protein no 0.21
    16 Rv1808 PPE family protein PPE32 no 0.20
    17 Rv2789c Probable acyl-CoA dehydrogenase FadE21 no 0.20
    18 Rv0179c Possible lipoprotein LprO no 0.20
    19 Rv1400c Probable lipase LipH no 0.20
    20 Rv0276 Conserved hypothetical protein no 0.20

    Or look for negative cofitness