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Gene
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Cofit
Protein
Homologs
Top cofit genes for Rv1869c from
Mycobacterium tuberculosis H37Rv
Probable reductase
KEGG:
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0426c
Possible transmembrane protein
no
0.34
2
Rv0100
Conserved hypothetical protein
no
0.32
3
Rv2615c
PE-PGRS family protein PE_PGRS45
no
0.30
4
Rv1209
Conserved protein
no
0.30
5
Rv0947c
Probable mycolyl transferase, pseudogene
no
0.30
6
Rv2269c
Hypothetical protein
no
0.29
7
Rv3034c
Possible transferase
no
0.29
8
Rv0625c
Probable conserved transmembrane protein
no
0.29
9
Rv0491
Two component sensory transduction protein RegX3 (transcriptional regulatory protein) (probably LuxR-family)
no
0.29
10
Rv0230c
Probable phosphotriesterase Php (parathion hydrolase) (PTE) (aryldialkylphosphatase) (paraoxonase) (a-esterase) (aryltriphosphatase) (paraoxon hydrolase)
no
0.29
11
Rv3885c
ESX conserved component EccE2. ESX-2 type VII secretion system protein. Possible membrane protein.
no
0.28
12
Rv1962A
Possible antitoxin VapB35
no
0.28
13
Rv1550
Probable fatty-acid-CoA ligase FadD11 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.27
14
Rv1489
Conserved protein
no
0.27
15
Rv2578c
Conserved hypothetical protein
no
0.27
16
Rv3000
Possible conserved transmembrane protein
no
0.27
17
Rv1785c
Probable cytochrome P450 143 Cyp143
no
0.27
18
Rv1266c
Probable transmembrane serine/threonine-protein kinase H PknH (protein kinase H) (STPK H)
no
0.27
19
Rv3307
Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP)
no
0.26
20
Rv3166c
Conserved hypothetical protein
no
0.26
Or look for
negative cofitness