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Gene
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Cofit
Protein
Homologs
Top cofit genes for Rv1839c from
Mycobacterium tuberculosis H37Rv
Possible antitoxin VapB13
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0737
Possible transcriptional regulatory protein
no
0.27
2
Rv0926c
Conserved hypothetical protein
no
0.26
3
Rv1825
Conserved protein
no
0.26
4
Rv1225c
Conserved hypothetical protein
no
0.25
5
Rv2590
Probable fatty-acid-CoA ligase FadD9 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.25
6
Rv3615c
ESX-1 secretion-associated protein EspC
no
0.24
7
Rv3477
PE family protein PE31
no
0.23
8
Rv0012
Probable conserved membrane protein
no
0.23
9
Rv2901c
Conserved protein
no
0.23
10
Rv1823
Conserved protein
no
0.22
11
Rv2298
Conserved protein
no
0.21
12
Rv0575c
Possible oxidoreductase
no
0.21
13
Rv1511
GDP-D-mannose dehydratase GmdA (GDP-mannose 4,6 dehydratase) (GMD)
no
0.21
14
Rv2880c
Conserved hypothetical protein
no
0.21
15
Rv3377c
Halimadienyl diphosphate synthase
no
0.21
16
Rv3508
PE-PGRS family protein PE_PGRS54
no
0.20
17
Rv1020
Probable transcription-repair coupling factor Mfd (TRCF)
no
0.20
18
Rv0579
Conserved hypothetical protein
no
0.20
19
Rv3513c
Probable fatty-acid-CoA ligase FadD18 (fragment) (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.20
20
Rv1771
L-gulono-1,4-lactone dehydrogenase
no
0.19
Or look for
negative cofitness