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  • Top cofit genes for Rv1730c from Mycobacterium tuberculosis H37Rv

    Possible penicillin-binding protein
    SEED: Beta-lactamase (EC 3.5.2.6)

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv0276 Conserved hypothetical protein no 0.39
    2 Rv0585c Probable conserved integral membrane protein no 0.37
    3 Rv3346c Conserved transmembrane protein no 0.35
    4 Rv2403c Probable conserved lipoprotein LppR no 0.32
    5 Rv3521 Conserved hypothetical protein no 0.32
    6 Rv1028c Probable sensor protein KdpD no 0.31
    7 Rv0980c PE-PGRS family protein PE_PGRS18 no 0.31
    8 Rv1282c Probable oligopeptide-transport integral membrane protein ABC transporter OppC no 0.30
    9 Rv3509c Probable acetohydroxyacid synthase IlvX (acetolactate synthase) no 0.30
    10 Rv0280 PPE family protein PPE3 no 0.29
    11 Rv1091 PE-PGRS family protein PE_PGRS22 no 0.29
    12 Rv1895 Possible dehydrogenase no 0.29
    13 Rv0760c Conserved protein no 0.28
    14 Rv0741 Probable transposase (fragment) no 0.28
    15 Rv0098 Probable fatty acyl CoA thioesterase type III FcoT no 0.28
    16 Rv1329c Probable ATP-dependent helicase DinG no 0.27
    17 Rv3344c PE-PGRS family protein PE_PGRS49 no 0.27
    18 Rv0279c PE-PGRS family protein PE_PGRS4 no 0.27
    19 Rv3511 PE-PGRS family protein PE_PGRS55 no 0.27
    20 Rv3157 Probable NADH dehydrogenase I (chain M) NUOK (NADH-ubiquinone oxidoreductase chain M) no 0.27

    Or look for negative cofitness