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Gene
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Cofit
Protein
Homologs
Top cofit genes for Rv1468c from
Mycobacterium tuberculosis H37Rv
PE-PGRS family protein PE_PGRS29
SEED: PE family protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv3590c
PE-PGRS family protein PE_PGRS58
no
0.27
2
Rv3089
Probable chain-fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)
no
0.27
3
Rv3901c
Possible membrane protein
no
0.25
4
Rv0424c
Hypothetical protein
no
0.25
5
Rv2107
PE family protein PE22
no
0.24
6
Rv0918
Conserved protein
no
0.24
7
Rv3071
Conserved hypothetical protein
no
0.23
8
Rv1207
Dihydropteroate synthase 2 FolP2 (DHPS 2) (dihydropteroate pyrophosphorylase 2)
no
0.22
9
Rv2762c
Conserved hypothetical protein
no
0.22
10
Rv1850
Urease alpha subunit UreC (urea amidohydrolase)
no
0.22
11
Rv0773c
Probable bifunctional acylase GgtA: cephalosporin acylase (GL-7ACA acylase) + gamma-glutamyltranspeptidase (GGT)
no
0.22
12
Rv2098c
PE-PGRS family protein PE_PGRS36
no
0.21
13
Rv2482c
Probable glycerol-3-phosphate acyltransferase PlsB2 (GPAT)
no
0.21
14
Rv1550
Probable fatty-acid-CoA ligase FadD11 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.21
15
Rv0578c
PE-PGRS family protein PE_PGRS7
no
0.21
16
Rv3491
Unknown protein
no
0.21
17
Rv0195
Possible two component transcriptional regulatory protein (probably LuxR-family)
no
0.20
18
Rv1148c
Conserved hypothetical protein
no
0.20
19
Rv0925c
Conserved protein
no
0.20
20
Rv1962c
Possible toxin VapC35. Contains PIN domain.
no
0.20
Or look for
negative cofitness