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  • Top cofit genes for Rv1277 from Mycobacterium tuberculosis H37Rv

    Conserved hypothetical protein
    SEED: DNA double-strand break repair protein Mre11

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv2095c Proteasome accessory factor C PafC no 0.62
    2 Rv2737c RecA protein (recombinase A) [contains: endonuclease PI-MTUI (MTU RecA intein)]. no 0.54
    3 Rv3202c Possible ATP-dependent DNA helicase no 0.49
    4 Rv1020 Probable transcription-repair coupling factor Mfd (TRCF) no 0.48
    5 Rv3201c Probable ATP-dependent DNA helicase no 0.48
    6 Rv1278 Hypothetical protein no 0.45
    7 Rv2096c Proteasome accessory factor B PafB no 0.44
    8 Rv0003 DNA replication and repair protein RecF (single-strand DNA binding protein) no 0.43
    9 Rv3585 DNA repair protein RadA (DNA repair protein SMS) no 0.42
    10 Rv3364c Conserved protein no 0.38
    11 Rv3365c Conserved protein no 0.36
    12 Rv1232c Conserved protein no 0.30
    13 Rv1108c Probable exodeoxyribonuclease VII (large subunit) XseA (exonuclease VII large subunit) no 0.30
    14 Rv2734 Conserved hypothetical protein no 0.30
    15 Rv2340c PE-PGRS family protein PE_PGRS39 no 0.28
    16 Rv1109c Conserved protein no 0.27
    17 Rv1834 Probable hydrolase no 0.26
    18 Rv3198c Probable ATP-dependent DNA helicase II UvrD2 no 0.26
    19 Rv0871 Probable cold shock-like protein B CspB no 0.26
    20 Rv0110 Probable conserved integral membrane protein no 0.26

    Or look for negative cofitness