Top cofit genes for Rv1258c from Mycobacterium tuberculosis H37Rv

Probable conserved integral membrane transport protein
SEED: Macrolide-efflux protein

Rank	Hit	Name	Description	Conserved?	Cofitness
1	Rv3610c		Membrane-bound protease FtsH (cell division protein)	no	0.32
2	Rv3273		Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase)	no	0.31
3	Rv3744		Metal sensor transcriptional regulator (ArsR-SmtB family)	no	0.30
4	Rv1280c		Probable periplasmic oligopeptide-binding lipoprotein OppA	no	0.28
5	Rv0059		Hypothetical protein	no	0.28
6	Rv0418		Probable lipoprotein aminopeptidase LpqL	no	0.27
7	Rv3272		Conserved hypothetical protein	no	0.27
8	Rv0262c		Aminoglycoside 2'-N-acetyltransferase Aac (Aac(2')-IC)	no	0.26
9	Rv2384		Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	no	0.26
10	Rv1808		PPE family protein PPE32	no	0.25
11	Rv1281c		Probable oligopeptide-transport ATP-binding protein ABC transporter OppD	no	0.25
12	Rv2776c		Probable oxidoreductase	no	0.24
13	Rv2560		Probable proline and glycine rich transmembrane protein	no	0.24
14	Rv1283c		Probable oligopeptide-transport integral membrane protein ABC transporter OppB	no	0.24
15	Rv1810		Conserved protein	no	0.23
16	Rv2500c		Possible acyl-CoA dehydrogenase FadE19 (MMGC)	no	0.23
17	Rv3548c		Probable short-chain type dehydrogenase/reductase	no	0.21
18	Rv3263		Probable DNA methylase (modification methylase) (methyltransferase)	no	0.21
19	Rv1398c		Possible antitoxin VapB10	no	0.21
20	Rv3445c		ESAT-6 like protein EsxU	no	0.20

Or look for negative cofitness