Top cofit genes for Rv1246c from Mycobacterium tuberculosis H37Rv

Toxin RelE
SEED: RelE/StbE replicon stabilization toxin

Rank Hit Name Description Conserved? Cofitness  
1 Rv0604 Probable conserved lipoprotein LpqO no 0.27
2 Rv0625c Probable conserved transmembrane protein no 0.27
3 Rv3547 Deazaflavin-dependent nitroreductase Ddn no 0.26
4 Rv0078 Probable transcriptional regulatory protein no 0.26
5 Rv3572 Unknown protein no 0.26
6 Rv2268c Probable cytochrome P450 128 Cyp128 no 0.25
7 Rv2345 Possible conserved transmembrane protein no 0.24
8 Rv3261 Probable F420 biosynthesis protein FbiA no 0.24
9 Rv3674c Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic)) no 0.23
10 Rv3885c ESX conserved component EccE2. ESX-2 type VII secretion system protein. Possible membrane protein. no 0.22
11 Rv2057c 50S ribosomal protein L33 RpmG1 no 0.22
12 Rv1749c Possible integral membrane protein no 0.21
13 Rv1318c Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase) no 0.21
14 Rv3018c PPE family protein PPE46 no 0.21
15 Rv2634c PE-PGRS family protein PE_PGRS46 no 0.20
16 Rv0834c PE-PGRS family protein PE_PGRS14 no 0.20
17 Rv3890c ESAT-6 like protein EsxC (ESAT-6 like protein 11) no 0.20
18 Rv3306c Probable amidohydrolase AmiB1 (aminohydrolase) no 0.20
19 Rv3344c PE-PGRS family protein PE_PGRS49 no 0.20
20 Rv3386 Possible transposase no 0.20

Or look for negative cofitness