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Cofit
Protein
Homologs
Top cofit genes for Rv1246c from
Mycobacterium tuberculosis H37Rv
Toxin RelE
SEED: RelE/StbE replicon stabilization toxin
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv0604
Probable conserved lipoprotein LpqO
no
0.27
2
Rv0625c
Probable conserved transmembrane protein
no
0.27
3
Rv3547
Deazaflavin-dependent nitroreductase Ddn
no
0.26
4
Rv0078
Probable transcriptional regulatory protein
no
0.26
5
Rv3572
Unknown protein
no
0.26
6
Rv2268c
Probable cytochrome P450 128 Cyp128
no
0.25
7
Rv2345
Possible conserved transmembrane protein
no
0.24
8
Rv3261
Probable F420 biosynthesis protein FbiA
no
0.24
9
Rv3674c
Probable endonuclease III Nth (DNA-(apurinic or apyrimidinic site)lyase) (AP lyase) (AP endonuclease class I) (endodeoxyribonuclease (apurinic or apyrimidinic)) (deoxyribonuclease (apurinic or apyrimidinic))
no
0.23
10
Rv3885c
ESX conserved component EccE2. ESX-2 type VII secretion system protein. Possible membrane protein.
no
0.22
11
Rv2057c
50S ribosomal protein L33 RpmG1
no
0.22
12
Rv1749c
Possible integral membrane protein
no
0.21
13
Rv1318c
Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase)
no
0.21
14
Rv3018c
PPE family protein PPE46
no
0.21
15
Rv2634c
PE-PGRS family protein PE_PGRS46
no
0.20
16
Rv0834c
PE-PGRS family protein PE_PGRS14
no
0.20
17
Rv3890c
ESAT-6 like protein EsxC (ESAT-6 like protein 11)
no
0.20
18
Rv3306c
Probable amidohydrolase AmiB1 (aminohydrolase)
no
0.20
19
Rv3344c
PE-PGRS family protein PE_PGRS49
no
0.20
20
Rv3386
Possible transposase
no
0.20
Or look for
negative cofitness