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  • Top cofit genes for Rv1033c from Mycobacterium tuberculosis H37Rv

    Two component transcriptional regulator TrcR
    SEED: DNA-binding response regulator TrcR
    KEGG: two-component system, OmpR family, response regulator TrcR

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv3169 Conserved protein no 0.32
    2 Rv2515c Conserved hypothetical protein no 0.31
    3 Rv2569c Conserved hypothetical protein no 0.29
    4 Rv1493 Probable methylmalonyl-CoA mutase large subunit MutB (MCM) no 0.28
    5 Rv2498c Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) no 0.27
    6 Rv2956 Conserved protein no 0.27
    7 Rv1661 Probable polyketide synthase Pks7 no 0.27
    8 Rv3533c PPE family protein PPE62 no 0.26
    9 Rv0020c Conserved protein with FHA domain, FhaA no 0.26
    10 Rv0309 Possible conserved exported protein no 0.26
    11 Rv1984c Probable cutinase precursor CFP21 no 0.26
    12 Rv1168c PPE family protein PPE17 no 0.26
    13 Rv1181 Probable polyketide beta-ketoacyl synthase Pks4 no 0.26
    14 Rv1009 Probable resuscitation-promoting factor RpfB no 0.25
    15 Rv1180 Probable polyketide beta-ketoacyl synthase Pks3 no 0.25
    16 Rv0223c Probable aldehyde dehydrogenase no 0.25
    17 Rv0566c Conserved protein no 0.25
    18 Rv0561c Possible oxidoreductase no 0.25
    19 Rv3405c Possible transcriptional regulatory protein no 0.24
    20 Rv3855 Transcriptional regulatory repressor protein (TetR-family) EthR no 0.24

    Or look for negative cofitness