Top cofit genes for Rv0939 from Mycobacterium tuberculosis H37Rv

Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase
SEED: Fumarylacetoacetase (EC 3.7.1.2)

Rank	Hit	Name	Description	Conserved?	Cofitness
1	Rv3774		Possible enoyl-CoA hydratase EchA21 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase)	no	0.45
2	Rv1729c		Possible S-adenosylmethionine-dependent methyltransferase	no	0.40
3	Rv2527		Possible toxin VapC17	no	0.39
4	Rv2184c		Conserved hypothetical protein	no	0.37
5	Rv3610c		Membrane-bound protease FtsH (cell division protein)	no	0.34
6	Rv1829		Conserved protein	no	0.34
7	Rv1290c		Conserved protein	no	0.33
8	Rv2316		Probable sugar-transport integral membrane protein ABC transporter UspA	no	0.32
9	Rv0965c		Conserved hypothetical protein	no	0.31
10	Rv0518		Possible exported protein	no	0.31
11	Rv3327		Probable transposase fusion protein	no	0.31
12	Rv3331		Probable sugar-transport integral membrane protein SugI	no	0.30
13	Rv1328		Probable glycogen phosphorylase GlgP	no	0.30
14	Rv2606c		Possible pyridoxine biosynthesis protein SnzP	no	0.30
15	Rv3010c		Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase)	no	0.30
16	Rv3816c		Possible acyltransferase	no	0.29
17	Rv3715c		Probable recombination protein RecR	no	0.29
18	Rv1320c		Possible adenylate cyclase (ATP pyrophosphate-lyase) (adenylyl cyclase)	no	0.29
19	Rv1995		Unknown protein	no	0.29
20	Rv1028c		Probable sensor protein KdpD	no	0.29

Or look for negative cofitness