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  • Top cofit genes for Rv0891c from Mycobacterium tuberculosis H37Rv

    Possible transcriptional regulatory protein
    SEED: Adenylyl cyclase class-3/4/guanylyl cyclase

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv0690c Conserved hypothetical protein no 0.29
    2 Rv0499 Conserved hypothetical protein no 0.28
    3 Rv1232c Conserved protein no 0.27
    4 Rv1728c Conserved hypothetical protein no 0.27
    5 Rv2615c PE-PGRS family protein PE_PGRS45 no 0.24
    6 Rv0454 Conserved hypothetical protein no 0.24
    7 Rv2636 Conserved hypothetical protein no 0.24
    8 Rv2536 Probable conserved transmembrane protein no 0.24
    9 Rv2826c Hypothetical protein no 0.22
    10 Rv1118c Conserved protein no 0.22
    11 Rv0469 Possible mycolic acid synthase UmaA no 0.21
    12 Rv2506 Probable transcriptional regulatory protein (probably TetR-family) no 0.21
    13 Rv3836 Conserved hypothetical protein no 0.21
    14 Rv0106 Conserved hypothetical protein no 0.21
    15 Rv0461 Probable transmembrane protein no 0.21
    16 Rv1804c Conserved protein no 0.21
    17 Rv1205 Conserved hypothetical protein no 0.21
    18 Rv0535 Probable 5'-methylthioadenosine phosphorylase Pnp (MTA phosphorylase) no 0.21
    19 Rv2671 Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reductase (HTP reductase) no 0.21
    20 Rv0931c Transmembrane serine/threonine-protein kinase D PknD (protein kinase D) (STPK D) no 0.20

    Or look for negative cofitness