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  • Top cofit genes for Rv0804 from Mycobacterium tuberculosis H37Rv

    Conserved hypothetical protein
    SEED: 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv1425 Possible triacylglycerol synthase (diacylglycerol acyltransferase) no 0.36
    2 Rv1329c Probable ATP-dependent helicase DinG no 0.30
    3 Rv1113 Possible antitoxin VapB32 no 0.27
    4 Rv3131 Conserved protein no 0.25
    5 Rv2546 Possible toxin VapC18 no 0.25
    6 Rv1881c Possible conserved lipoprotein LppE no 0.25
    7 Rv2124c 5-methyltetrahydrofolate--homocystein methyltransferase MetH (methionine synthase, vitamin-B12 dependent isozyme) (ms) no 0.24
    8 Rv2513 Hypothetical protein no 0.23
    9 Rv2231A Possible toxin VapC16 no 0.23
    10 Rv3344c PE-PGRS family protein PE_PGRS49 no 0.22
    11 Rv3300c Conserved hypothetical protein no 0.22
    12 Rv2638 Conserved hypothetical protein no 0.22
    13 Rv2963 Probable integral membrane protein no 0.22
    14 Rv3233c Possible triacylglycerol synthase (diacylglycerol acyltransferase) no 0.22
    15 Rv1187 Probable pyrroline-5-carboxylate dehydrogenase RocA no 0.22
    16 Rv0203 Possible exported protein no 0.22
    17 Rv3691 Conserved protein no 0.21
    18 Rv3313c Probable adenosine deaminase Add (adenosine aminohydrolase) no 0.21
    19 Rv0496 Conserved hypothetical protein no 0.21
    20 Rv3393 Probable nucleoside hydrolase IunH (purine nucleosidase) no 0.21

    Or look for negative cofitness