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  • Top cofit genes for Rv0693 from Mycobacterium tuberculosis H37Rv

    Probable coenzyme PQQ synthesis protein E PqqE (coenzyme PQQ synthesis protein III)
    SEED: Mycofactocin radical SAM maturase

    Rank Hit Name Description Conserved? Cofitness  
    1 Rv0694 Possible L-lactate dehydrogenase (cytochrome) LldD1 no 0.45
    2 Rv0692 Conserved hypothetical protein no 0.45
    3 Rv0761c Possible zinc-containing alcohol dehydrogenase NAD dependent AdhB no 0.44
    4 Rv3295 Probable transcriptional regulatory protein (probably TetR-family) no 0.43
    5 Rv1239c Possible magnesium and cobalt transport transmembrane protein CorA no 0.42
    6 Rv0458 Probable aldehyde dehydrogenase 0.76 0.39
    7 Rv1538c Probable L-aparaginase AnsA no 0.38
    8 Rv0696 Probable membrane sugar transferase no 0.38
    9 Rv0346c Possible L-asparagine permease AnsP2 (L-asparagine transport protein) no 0.34
    10 Rv1707 Probable conserved transmembrane protein 0.85 0.31
    11 Rv0695 Conserved hypothetical protein no 0.31
    12 Rv2633c Hypothetical protein no 0.31
    13 Rv3236c Probable conserved integral membrane transport protein no 0.31
    14 Rv2127 L-asparagine permease AnsP1 no 0.31
    15 Rv0660c Possible antitoxin MazE2 no 0.29
    16 Rv3331 Probable sugar-transport integral membrane protein SugI 0.36 0.29
    17 Rv0037c Probable conserved integral membrane protein no 0.28
    18 Rv1455 Conserved protein no 0.27
    19 Rv3553 Possible oxidoreductase 0.42 0.27
    20 Rv3816c Possible acyltransferase no 0.26

    Or look for negative cofitness