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Gene
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Cofit
Protein
Homologs
Top cofit genes for Rv0669c from
Mycobacterium tuberculosis H37Rv
Possible hydrolase
SEED: Alkaline ceramidase
KEGG:
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv1217c
Probable tetronasin-transport integral membrane protein ABC transporter
no
0.37
2
Rv3000
Possible conserved transmembrane protein
no
0.35
3
Rv0146
Possible S-adenosylmethionine-dependent methyltransferase
no
0.29
4
Rv0426c
Possible transmembrane protein
no
0.29
5
Rv3166c
Conserved hypothetical protein
no
0.29
6
Rv1359
Probable transcriptional regulatory protein
no
0.28
7
Rv1929c
Conserved hypothetical protein
no
0.28
8
Rv1639c
Conserved hypothetical membrane protein
no
0.27
9
Rv3575c
Transcriptional regulatory protein (probably LacI-family)
no
0.27
10
Rv3546
Probable acetyl-CoA acetyltransferase FadA5 (acetoacetyl-CoA thiolase)
no
0.26
11
Rv0854
Conserved protein
no
0.26
12
Rv0922
Possible transposase
no
0.26
13
Rv0625c
Probable conserved transmembrane protein
no
0.25
14
Rv3202c
Possible ATP-dependent DNA helicase
no
0.25
15
Rv3827c
Possible transposase
no
0.25
16
Rv3759c
Possible osmoprotectant (glycine betaine/carnitine/choline/L-proline) binding lipoprotein ProX
no
0.25
17
Rv0765c
Probable oxidoreductase
no
0.25
18
Rv2293c
Conserved hypothetical protein
no
0.25
19
Rv1450c
PE-PGRS family protein PE_PGRS27
no
0.25
20
Rv3307
Probable purine nucleoside phosphorylase DeoD (inosine phosphorylase) (PNP)
no
0.25
Or look for
negative cofitness