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Gene
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Cofit
Protein
Homologs
Top cofit genes for Rv0589 from
Mycobacterium tuberculosis H37Rv
Mce-family protein Mce2A
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv2187
Long-chain-fatty-acid-CoA ligase FadD15 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)
no
0.33
2
Rv2531c
Probable amino acid decarboxylase
no
0.29
3
Rv1747
Probable conserved transmembrane ATP-binding protein ABC transporter
no
0.29
4
Rv0676c
Probable conserved transmembrane transport protein MmpL5
no
0.28
5
Rv1345
Probable fatty acyl-AMP ligase MbtM
no
0.28
6
Rv1049
Probable transcriptional repressor protein
no
0.27
7
Rv1151c
Transcriptional regulatory protein
no
0.27
8
Rv2911
Probable penicillin-binding protein DacB2 (D-alanyl-D-alanine carboxypeptidase) (DD-peptidase) (DD-carboxypeptidase) (PBP) (DD-transpeptidase) (serine-type D-ala-D-ala carboxypeptidase) (D-amino acid hydrolase)
no
0.27
9
Rv3004
Low molecular weight protein antigen 6 (CFP-6)
no
0.26
10
Rv3912
Hypothetical alanine rich protein
no
0.25
11
Rv2273
Probable conserved transmembrane protein
no
0.24
12
Rv3066
Probable transcriptional regulatory protein (probably DeoR-family)
no
0.24
13
Rv1673c
Conserved hypothetical protein
no
0.24
14
Rv1159
Mannosyltransferase PimE
no
0.23
15
Rv3480c
Possible triacylglycerol synthase (diacylglycerol acyltransferase)
no
0.23
16
Rv3254
Conserved hypothetical protein
no
0.23
17
Rv1590
Conserved hypothetical protein
no
0.23
18
Rv1895
Possible dehydrogenase
no
0.23
19
Rv0749
Possible toxin VapC31. Contains PIN domain.
no
0.23
20
Rv3707c
Conserved hypothetical protein
no
0.22
Or look for
negative cofitness