Top cofit genes for Rv0516c from Mycobacterium tuberculosis H37Rv

Possible anti-anti-sigma factor
SEED: Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV

Rank Hit Name Description Conserved? Cofitness  
1 Rv0886 Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) no 0.48
2 Rv0243 Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (beta-ketothiolase) no 0.46
3 Rv3140 Probable acyl-CoA dehydrogenase FadE23 no 0.40
4 Rv0885 Conserved hypothetical protein no 0.36
5 Rv0634A Unknown protein no 0.35
6 Rv2411c Conserved hypothetical protein no 0.34
7 Rv3772 Probable histidinol-phosphate aminotransferase HisC2 (imidazole acetol-phosphate transaminase) (imidazolylacetolphosphate aminotransferase) no 0.34
8 Rv0643c Methoxy mycolic acid synthase 3 MmaA3 (methyl mycolic acid synthase 3) (MMA3) (hydroxy mycolic acid synthase) no 0.34
9 Rv3066 Probable transcriptional regulatory protein (probably DeoR-family) no 0.34
10 Rv3803c Secreted MPT51/MPB51 antigen protein FbpD (MPT51/MPB51 antigen 85 complex C) (AG58C) (mycolyl transferase 85C) (fibronectin-binding protein C) (85C) no 0.34
11 Rv1753c PPE family protein PPE24 no 0.34
12 Rv1569 Probable 8-amino-7-oxononanoate synthase BioF1 (AONS) (8-amino-7-ketopelargonate synthase) (7-keto-8-amino-pelargonic acid synthetase) (7-KAP synthetase) (L-alanine--pimelyl CoA ligase) no 0.34
13 Rv1272c Probable drugs-transport transmembrane ATP-binding protein ABC transporter no 0.33
14 Rv1589 Probable biotin synthetase BioB no 0.32
15 Rv2606c Possible pyridoxine biosynthesis protein SnzP no 0.32
16 Rv2476c Probable NAD-dependent glutamate dehydrogenase Gdh (NAD-Gdh) (NAD-dependent glutamic dehydrogenase) no 0.32
17 Rv0037c Probable conserved integral membrane protein no 0.31
18 Rv3139 Probable acyl-CoA dehydrogenase FadE24 no 0.31
19 Rv0280 PPE family protein PPE3 no 0.31
20 Rv1273c Probable drugs-transport transmembrane ATP-binding protein ABC transporter no 0.30

Or look for negative cofitness