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Cofit
Protein
Homologs
Top cofit genes for Rv0461 from
Mycobacterium tuberculosis H37Rv
Probable transmembrane protein
Rank
Hit
Name
Description
Conserved?
Cofitness
1
Rv1020
Probable transcription-repair coupling factor Mfd (TRCF)
no
0.39
2
Rv0686
Probable membrane protein
no
0.36
3
Rv0937c
DNA end-binding protein, Mku
no
0.36
4
Rv3755c
Conserved protein
no
0.32
5
Rv2684
Probable arsenic-transport integral membrane protein ArsA
no
0.32
6
Rv1253
Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog)
no
0.31
7
Rv0075
Probable aminotransferase
no
0.31
8
Rv1143
Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase)
no
0.30
9
Rv1564c
Probable maltooligosyltrehalose synthase TreX
no
0.30
10
Rv3198c
Probable ATP-dependent DNA helicase II UvrD2
no
0.30
11
Rv2427c
Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase)
no
0.29
12
Rv0926c
Conserved hypothetical protein
no
0.29
13
Rv0117
Oxidative stress response regulatory protein OxyS
no
0.29
14
Rv1179c
Unknown protein
no
0.28
15
Rv0474
Probable transcriptional regulatory protein
no
0.28
16
Rv1114
Possible toxin VapC32. Contains PIN domain.
no
0.28
17
Rv1286
Probable bifunctional enzyme CysN/CysC: sulfate adenyltransferase (subunit 1) + adenylylsulfate kinase
no
0.28
18
Rv0085
Possible hydrogenase HycP
no
0.27
19
Rv3750c
Possible excisionase
no
0.27
20
Rv2086
Conserved hypothetical protein
no
0.27
Or look for
negative cofitness