Top cofit genes for Pf6N2E2_2194 from Pseudomonas fluorescens FW300-N2E2

3-methylcrotonyl-CoA carboxylase, alpha (biotin-containing) subunit (EC 6.4.1.4) (from data)
Original annotation: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
SEED: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
KEGG: 3-methylcrotonyl-CoA carboxylase alpha subunit

Rank Hit Name Description Conserved? Cofitness  
1 Pf6N2E2_2192 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) 0.98 0.83
2 Pf6N2E2_2191 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) 0.99 0.82
3 Pf6N2E2_2193 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) (from data) 0.97 0.75
4 Pf6N2E2_480 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) (EC 1.2.4.4) (from data) 0.97 0.59
5 Pf6N2E2_2189 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) 0.97 0.56
6 Pf6N2E2_479 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) 0.97 0.53
7 Pf6N2E2_2924 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, permease component 2 LivM (from data) 0.98 0.51
8 Pf6N2E2_2188 Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family 0.55 0.51
9 Pf6N2E2_481 branched-chain alpha-ketoacid dehydrogenase, E1 component alpha subunit (EC 1.2.4.4) (from data) 0.96 0.51
10 Pf6N2E2_3580 Branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) 0.46 0.50
11 Pf6N2E2_2923 ABC transporter for L-leucine/L-phenylalanine/D-alanine, permease component 1 LivH (from data) 0.98 0.49
12 Pf6N2E2_2921 ABC transporter for L-leucine/L-phenylalanine/D-alanine, substrate-binding component LivK (from data) 0.96 0.49
13 Pf6N2E2_3578 Branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) 0.51 0.48
14 Pf6N2E2_3579 High-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) 0.51 0.48
15 Pf6N2E2_482 Transcriptional regulator BkdR of isoleucine and valine catabolism operon 0.60 0.44
16 Pf6N2E2_279 Isocitrate lyase (EC 4.1.3.1) 0.79 0.43
17 Pf6N2E2_1147 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) 0.80 0.42
18 Pf6N2E2_3576 Branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) 0.41 0.42
19 Pf6N2E2_2696 Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-) 0.98 0.41
20 Pf6N2E2_478 Dihydrolipoyl dehydrogenase (EC 1.8.1.4) (from data) 0.86 0.40

Or look for negative cofitness