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  • Top cofit genes for MMP_RS05105 from Methanococcus maripaludis S2

    thymidylate synthase
    SEED: Thymidylate synthase (EC 2.1.1.45)
    KEGG: thymidylate synthase

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS05095 CO dehydrogenase/acetyl-CoA synthase complex subunit epsilon no 0.52
    2 MMP_RS05060 AAA family ATPase no 0.51
    3 MMP_RS05070 4Fe-4S dicluster domain-containing protein no 0.51
    4 MMP_RS05100 CO dehydrogenase/acetyl-CoA synthase complex subunit alpha no 0.51
    5 MMP_RS05075 acetyl-CoA decarbonylase/synthase complex subunit gamma no 0.50
    6 MMP_RS05080 acetyl-CoA decarbonylase/synthase complex subunit delta no 0.49
    7 MMP_RS05085 AAA family ATPase no 0.49
    8 MMP_RS05090 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta no 0.49
    9 MMP_RS05055 DUF166 domain-containing protein no 0.48
    10 MMP_RS07720 4Fe-4S binding protein no 0.42
    11 MMP_RS05765 M42 family metallopeptidase 0.48 0.38
    12 MMP_RS05065 CooT family nickel-binding protein no 0.37
    13 MMP_RS07365 2-phosphoglycerate kinase no 0.37
    14 MMP_RS08645 UPF0179 family protein no 0.34
    15 MMP_RS02170 CBS domain-containing protein no 0.34
    16 MMP_RS06975 sulfide-dependent adenosine diphosphate thiazole synthase no 0.33
    17 MMP_RS06605 DUF5814 domain-containing protein no 0.32
    18 MMP_RS00290 hypothetical protein 0.40 0.32
    19 MMP_RS07345 glycine synthesis protein GlyXL (from data) no 0.29
    20 MMP_RS08655 phosphoadenosine phosphosulfate reductase family protein no 0.29

    Or look for negative cofitness