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  • Top cofit genes for MMP_RS04955 from Methanococcus maripaludis S2

    DNA topoisomerase I
    SEED: DNA topoisomerase I (EC 5.99.1.2)
    KEGG: DNA topoisomerase I

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS08660 DHH family phosphoesterase no 0.72
    2 MMP_RS05295 minichromosome maintenance protein MCM no 0.69
    3 MMP_RS05535 hypothetical protein no 0.66
    4 MMP_RS06725 hypothetical protein no 0.63
    5 MMP_RS04850 UPF0254 family protein no 0.61
    6 MMP_RS00810 topoisomerase DNA-binding C4 zinc finger domain-containing protein no 0.60
    7 MMP_RS07695 DUF3236 domain-containing protein no 0.58
    8 MMP_RS03700 sodium:proton antiporter no 0.58
    9 MMP_RS01875 N-acetyltransferase no 0.57
    10 MMP_RS05560 deoxyuridine 5'-triphosphate nucleotidohydrolase no 0.57
    11 MMP_RS02245 hypothetical protein 0.61 0.57
    12 MMP_RS00040 TIGR03576 family pyridoxal phosphate-dependent enzyme no 0.57
    13 MMP_RS01900 hypothetical protein no 0.57
    14 MMP_RS02145 winged helix-turn-helix transcriptional regulator no 0.56
    15 MMP_RS05640 UTP--glucose-1-phosphate uridylyltransferase GalU 0.63 0.56
    16 MMP_RS07390 cell division protein FtsZ no 0.56
    17 MMP_RS06395 ThiF family adenylyltransferase no 0.56
    18 MMP_RS00725 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC no 0.56
    19 MMP_RS01885 Gfo/Idh/MocA family oxidoreductase no 0.55
    20 MMP_RS01880 DegT/DnrJ/EryC1/StrS family aminotransferase 0.40 0.55

    Or look for negative cofitness