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  • Top cofit genes for MMP_RS03540 from Methanococcus maripaludis S2

    DUF2178 domain-containing protein
    SEED: conserved hypothetical archaeal protein

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS03535 helix-turn-helix transcriptional regulator no 0.54
    2 MMP_RS05145 hypothetical protein no 0.48
    3 MMP_RS07620 energy-coupling factor ABC transporter substrate-binding protein no 0.47
    4 MMP_RS07615 energy-coupling factor ABC transporter permease no 0.41
    5 MMP_RS05445 CoB--CoM heterodisulfide reductase subunit B no 0.40
    6 MMP_RS07555 monovalent cation/H+ antiporter subunit E no 0.33
    7 MMP_RS05450 CoB--CoM heterodisulfide reductase subunit C no 0.33
    8 MMP_RS02475 hypothetical protein no 0.32
    9 MMP_RS02800 nucleotidyltransferase domain-containing protein no 0.31
    10 MMP_RS02450 hypothetical protein no 0.31
    11 MMP_RS03700 sodium:proton antiporter no 0.31
    12 MMP_RS08675 class III signal peptide-containing protein no 0.26
    13 MMP_RS03460 U32 family peptidase no 0.25
    14 MMP_RS09035 hypothetical protein no 0.24
    15 MMP_RS05620 radical SAM protein no 0.24
    16 MMP_RS03080 universal stress protein no 0.23
    17 MMP_RS05925 small nuclear ribonucleoprotein no 0.23
    18 MMP_RS01665 DUF2111 domain-containing protein no 0.23
    19 MMP_RS04060 hypothetical protein no 0.22
    20 MMP_RS04665 SBBP repeat-containing protein no 0.22

    Or look for negative cofitness