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  • Top cofit genes for MMP_RS02960 from Methanococcus maripaludis S2

    class I SAM-dependent methyltransferase family protein
    SEED: tRNA methylase Trm12p Wyeosine biosynthesis

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS07410 4-demethylwyosine synthase TYW1 0.80 0.68
    2 MMP_RS04785 hypothetical protein no 0.52
    3 MMP_RS04790 4-hydroxy-tetrahydrodipicolinate reductase no 0.51
    4 MMP_RS05930 3-isopropylmalate dehydratase large subunit no 0.50
    5 MMP_RS00530 tRNA pseudouridine(54/55) synthase Pus10 0.57 0.49
    6 MMP_RS05500 2-isopropylmalate synthase no 0.47
    7 MMP_RS03420 acetolactate synthase small subunit no 0.47
    8 MMP_RS07955 FumA C-terminus/TtdB family hydratase beta subunit no 0.47
    9 MMP_RS03790 hypothetical protein no 0.47
    10 MMP_RS05265 2-isopropylmalate synthase no 0.46
    11 MMP_RS07850 prephenate dehydratase no 0.46
    12 MMP_RS03450 glycine synthesis protein GlyXS (from data) no 0.45
    13 MMP_RS08330 NADH-quinone oxidoreductase subunit H no 0.43
    14 MMP_RS01455 nickel pincer cofactor biosynthesis protein LarC no 0.42
    15 MMP_RS04215 nickel pincer cofactor biosynthesis protein LarB no 0.42
    16 MMP_RS07875 hypothetical protein no 0.42
    17 MMP_RS06375 ATP-dependent sacrificial sulfur transferase LarE no 0.41
    18 MMP_RS07185 pyridoxal phosphate-dependent aminotransferase no 0.41
    19 MMP_RS01830 tRNA-Val no 0.41
    20 MMP_RS05425 monovalent cation/H+ antiporter complex subunit F no 0.41

    Or look for negative cofitness