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  • Top cofit genes for MMP_RS01045 from Methanococcus maripaludis S2

    diphthamide biosynthesis enzyme Dph2
    SEED: diptheria toxin resistance protein required for diphthamide biosynthesis (Saccharomyces)-like 1
    KEGG: diphthamide synthase subunit DPH2

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS01840 TIGR00289 family protein 0.79 0.87
    2 MMP_RS03095 diphthine synthase 0.88 0.86
    3 MMP_RS06980 tRNA 2-thiocytidine biosynthesis TtcA family protein 0.74 0.82
    4 MMP_RS07750 DUF357 domain-containing protein no 0.77
    5 MMP_RS01725 class I SAM-dependent methyltransferase family protein 0.78 0.74
    6 MMP_RS00110 hypothetical protein no 0.74
    7 MMP_RS02195 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase no 0.73
    8 MMP_RS03400 archease no 0.73
    9 MMP_RS06885 50S ribosome-binding GTPase no 0.72
    10 MMP_RS06925 ribonuclease VapC4 0.61 0.72
    11 MMP_RS07580 DUF356 domain-containing protein no 0.72
    12 MMP_RS03140 hypothetical protein no 0.71
    13 MMP_RS01895 flippase no 0.71
    14 MMP_RS06130 peptidylprolyl isomerase no 0.70
    15 MMP_RS03145 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase no 0.70
    16 MMP_RS04775 adenosylhomocysteinase no 0.70
    17 MMP_RS01220 hypothetical protein 0.64 0.69
    18 MMP_RS05345 hypothetical protein no 0.69
    19 MMP_RS02345 GTP-dependent dephospho-CoA kinase family protein no 0.69
    20 MMP_RS03025 molybdenum cofactor guanylyltransferase no 0.69

    Or look for negative cofitness