Top cofit genes for MMP_RS00730 from Methanococcus maripaludis S2

5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
SEED: Biotin synthase-related protein in some methanogens
KEGG: biotin synthetase

Rank Hit Name Description Conserved? Cofitness  
1 MMP_RS00725 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC 0.98 0.94
2 MMP_RS07700 DUF1188 domain-containing protein 0.88 0.92
3 MMP_RS04850 UPF0254 family protein 0.96 0.92
4 MMP_RS07695 DUF3236 domain-containing protein 0.92 0.91
5 MMP_RS00735 5 10-methenyltetrahydromethanopterin hydrogenase 0.96 0.90
6 MMP_RS06395 ThiF family adenylyltransferase 0.96 0.88
7 MMP_RS00315 Nif3-like dinuclear metal center hexameric protein 0.85 0.85
8 MMP_RS06725 hypothetical protein 0.66 0.73
9 MMP_RS05295 minichromosome maintenance protein MCM 0.72 0.57
10 MMP_RS06900 coenzyme F420-reducing hydrogenase FrhD protein no 0.55
11 MMP_RS04955 DNA topoisomerase I no 0.52
12 MMP_RS06015 flavodoxin family protein 0.68 0.49
13 MMP_RS07115 MBL fold metallo-hydrolase no 0.47
14 MMP_RS05535 hypothetical protein no 0.47
15 MMP_RS04440 nitrogenase iron protein no 0.44
16 MMP_RS04450 P-II family nitrogen regulator no 0.44
17 MMP_RS00310 CBS domain-containing protein no 0.44
18 MMP_RS04465 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE no 0.44
19 MMP_RS08500 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT no 0.43
20 MMP_RS02245 hypothetical protein no 0.43

Or look for negative cofitness