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  • Top cofit genes for MMP_RS00725 from Methanococcus maripaludis S2

    5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
    SEED: Uncharacterized protein MJ0787

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS04850 UPF0254 family protein 0.97 0.96
    2 MMP_RS07700 DUF1188 domain-containing protein 0.87 0.94
    3 MMP_RS07695 DUF3236 domain-containing protein 0.92 0.94
    4 MMP_RS00730 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB 0.98 0.94
    5 MMP_RS00735 5 10-methenyltetrahydromethanopterin hydrogenase 0.95 0.93
    6 MMP_RS06395 ThiF family adenylyltransferase 0.96 0.90
    7 MMP_RS00315 Nif3-like dinuclear metal center hexameric protein 0.85 0.88
    8 MMP_RS06725 hypothetical protein 0.65 0.75
    9 MMP_RS06900 coenzyme F420-reducing hydrogenase FrhD protein no 0.61
    10 MMP_RS05295 minichromosome maintenance protein MCM 0.73 0.60
    11 MMP_RS04955 DNA topoisomerase I no 0.56
    12 MMP_RS05535 hypothetical protein no 0.50
    13 MMP_RS02245 hypothetical protein no 0.48
    14 MMP_RS00310 CBS domain-containing protein no 0.47
    15 MMP_RS07115 MBL fold metallo-hydrolase no 0.47
    16 MMP_RS03700 sodium:proton antiporter no 0.46
    17 MMP_RS00810 topoisomerase DNA-binding C4 zinc finger domain-containing protein no 0.46
    18 MMP_RS04450 P-II family nitrogen regulator no 0.45
    19 MMP_RS07355 transcription factor S 0.57 0.45
    20 MMP_RS04440 nitrogenase iron protein no 0.45

    Or look for negative cofitness