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  • Top cofit genes for MMP_RS00445 from Methanococcus maripaludis S2

    7-carboxy-7-deazaguanine synthase QueE
    SEED: Queuosine Biosynthesis QueE Radical SAM

    Rank Hit Name Description Conserved? Cofitness  
    1 MMP_RS03210 tRNA guanosine(15) transglycosylase TgtA no 0.38
    2 MMP_RS05245 archaeosine biosynthesis radical SAM protein RaSEA no 0.35
    3 MMP_RS00115 radical SAM protein no 0.33
    4 MMP_RS00895 hypothetical protein no 0.33
    5 MMP_RS00050 AarF/UbiB family protein no 0.28
    6 MMP_RS02190 sulfopyruvate decarboxylase subunit alpha no 0.28
    7 MMP_RS03095 diphthine synthase no 0.28
    8 MMP_RS07680 DUF366 family protein 0.65 0.27
    9 MMP_RS01840 TIGR00289 family protein no 0.27
    10 MMP_RS03405 RNA 3'-terminal phosphate cyclase no 0.26
    11 MMP_RS01045 diphthamide biosynthesis enzyme Dph2 no 0.26
    12 MMP_RS06430 6-carboxytetrahydropterin synthase QueD 0.79 0.26
    13 MMP_RS01780 TrmJ/YjtD family RNA methyltransferase no 0.25
    14 MMP_RS01365 archaeal proteasome endopeptidase complex subunit alpha no 0.25
    15 MMP_RS05440 winged helix-turn-helix transcriptional regulator no 0.25
    16 MMP_RS08690 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 no 0.25
    17 MMP_RS08820 hypothetical protein no 0.25
    18 MMP_RS00900 50S ribosomal protein L39e no 0.24
    19 MMP_RS01005 riboflavin synthase no 0.24
    20 MMP_RS02800 nucleotidyltransferase domain-containing protein no 0.24

    Or look for negative cofitness