Top cofit genes for H281DRAFT_01346 from Paraburkholderia bryophila 376MFSha3.1

isovaleryl-CoA dehydrogenase
SEED: Isovaleryl-CoA dehydrogenase (EC 1.3.8.4); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1)

Rank Hit Name Description Conserved? Cofitness  
1 H281DRAFT_01345 3-methylcrotonyl-CoA carboxylase beta subunit 0.99 0.78
2 H281DRAFT_02101 hydroxymethylglutaryl-CoA lyase 0.99 0.71
3 H281DRAFT_01203 acetyl-CoA synthetase 0.54 0.68
4 H281DRAFT_02100 glyoxylate/hydroxypyruvate reductase A 0.69 0.67
5 H281DRAFT_01343 3-methylcrotonoyl-CoA carboxylase, alpha subunit 0.99 0.64
6 H281DRAFT_01199 Enoyl-CoA hydratase/carnithine racemase 0.82 0.62
7 H281DRAFT_01205 transcriptional regulator, AraC family 0.82 0.52
8 H281DRAFT_01201 3-hydroxyisobutyrate dehydrogenase 0.79 0.51
9 H281DRAFT_01202 methylmalonate-semialdehyde dehydrogenase [acylating] 0.81 0.50
10 H281DRAFT_01200 short chain enoyl-CoA hydratase (EC 4.2.1.17) no 0.47
11 H281DRAFT_04633 (3S)-malyl-CoA thioesterase 0.65 0.42
12 H281DRAFT_04193 branched chain amino acid aminotransferase apoenzyme 0.86 0.38
13 H281DRAFT_00576 malate synthase 0.56 0.36
14 H281DRAFT_05565 Permeases of the drug/metabolite transporter (DMT) superfamily no 0.36
15 H281DRAFT_04172 transcriptional regulator, TetR family 0.35 0.36
16 H281DRAFT_04495 3-oxoacid CoA-transferase subunit A 0.94 0.35
17 H281DRAFT_04021 3,4-dihydroxy-2-butanone 4-phosphate synthase /GTP cyclohydrolase II 0.50 0.34
18 H281DRAFT_00580 isocitrate lyase 0.90 0.34
19 H281DRAFT_01204 hypothetical protein 0.77 0.34
20 H281DRAFT_00296 poly(3-hydroxybutyrate) depolymerase 0.66 0.32

Or look for negative cofitness