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  • Top cofit genes for BWI76_RS00975 from Klebsiella michiganensis M5al

    dihydroxy-acid dehydratase
    SEED: Dihydroxy-acid dehydratase (EC 4.2.1.9)

    Rank Hit Name Description Conserved? Cofitness  
    1 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.99 0.95
    2 BWI76_RS04255 threonine synthase 0.99 0.95
    3 BWI76_RS04245 bifunctional aspartate kinase/homoserine dehydrogenase I 0.99 0.95
    4 BWI76_RS00990 ketol-acid reductoisomerase 1.00 0.95
    5 BWI76_RS00845 N-acetyl-gamma-glutamyl-phosphate reductase 0.99 0.95
    6 BWI76_RS03010 ornithine carbamoyltransferase 0.98 0.95
    7 BWI76_RS00855 argininosuccinate lyase 0.99 0.94
    8 BWI76_RS00980 PLP-dependent threonine dehydratase 0.99 0.94
    9 BWI76_RS04250 homoserine kinase 0.99 0.93
    10 BWI76_RS04680 2-isopropylmalate synthase 0.99 0.93
    11 BWI76_RS00850 acetylglutamate kinase 0.98 0.93
    12 BWI76_RS25115 argininosuccinate synthase 0.99 0.93
    13 BWI76_RS04670 3-isopropylmalate dehydratase large subunit 1.00 0.93
    14 BWI76_RS23220 amino-acid N-acetyltransferase 0.99 0.93
    15 BWI76_RS18940 imidazole glycerol phosphate synthase subunit HisH 0.99 0.92
    16 BWI76_RS11840 tryptophan synthase subunit alpha 0.99 0.92
    17 BWI76_RS04675 3-isopropylmalate dehydrogenase 0.99 0.92
    18 BWI76_RS18935 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase 0.99 0.92
    19 BWI76_RS11845 tryptophan synthase subunit beta 0.99 0.92
    20 BWI76_RS04240 thr operon leader peptide no 0.92

    Or look for negative cofitness