Top cofit genes for Rru_A1823 from Rhodospirillum rubrum S1H

3,4-Dihydroxy-2-butanone 4-phosphate synthase (NCBI)
SEED: 3,4-dihydroxy-2-butanone 4-phosphate synthase (EC 4.1.99.12) / GTP cyclohydrolase II (EC 3.5.4.25)
KEGG: 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II

Rank	Hit	Name	Description	Conserved?	Cofitness
1	Rru_A2250		ABC transporter component (NCBI)	no	0.74
2	Rru_A2201		Peptidase S1C, Do (NCBI)	0.28	0.72
3	Rru_A0464		hypothetical protein (NCBI)	no	0.68
4	Rru_A1258		hypothetical protein (NCBI)	no	0.67
5	Rru_A3137		Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) (NCBI)	no	0.67
6	Rru_A1708		hypothetical protein (NCBI)	no	0.66
7	Rru_A1927		Acetyl-CoA hydrolase (NCBI)	0.42	0.66
8	Rru_A0588		Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like (NCBI)	0.23	0.66
9	Rru_A1658		AMP-dependent synthetase and ligase (NCBI)	no	0.64
10	Rru_A1002		Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine (NCBI)	no	0.63
11	Rru_A1618		hypothetical protein (NCBI)	no	0.63
12	Rru_A2634		Cobalt transport protein (NCBI)	no	0.62
13	Rru_A0041		Cytochrome c, class II (NCBI)	no	0.61
14	Rru_A0251		Transcriptional Regulator, AraC family (NCBI)	no	0.61
15	Rru_A2910		Mammalian cell entry related (NCBI)	no	0.61
16	Rru_A0602		Phosphate uptake regulator, PhoU (NCBI)	0.23	0.60
17	Rru_A0585		ABC transporter component (NCBI)	0.33	0.60
18	Rru_A2567		Putative diguanylate cyclase (GGDEF domain) (NCBI)	no	0.59
19	Rru_A2649		extracellular endo alpha-1 4 polygalactosaminidase or related polysaccharide hydrolase-like (NCBI)	no	0.59
20	Rru_A3242		Transcriptional Regulator, XRE family (NCBI)	no	0.59

Or look for negative cofitness