Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt DZA65_RS04865 and DZA65_RS04870 are separated by 697 nucleotides DZA65_RS04870 and DZA65_RS04875 are separated by 79 nucleotides DZA65_RS04875 and DZA65_RS04880 are separated by 78 nucleotides
DZA65_RS04865: DZA65_RS04865 - DNA topoisomerase III, at 1,007,439 to 1,009,463
_RS04865
DZA65_RS04870: DZA65_RS04870 - DUF3577 domain-containing protein, at 1,010,161 to 1,010,640
_RS04870
DZA65_RS04875: DZA65_RS04875 - hypothetical protein, at 1,010,720 to 1,010,947
_RS04875
DZA65_RS04880: DZA65_RS04880 - single-stranded DNA-binding protein, at 1,011,026 to 1,011,508
_RS04880
Position (kb)
1010
1011 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1009.271 kb on + strand at 1009.271 kb on + strand at 1009.271 kb on + strand at 1009.272 kb on - strand at 1009.295 kb on + strand at 1009.295 kb on + strand at 1009.295 kb on + strand at 1009.295 kb on + strand at 1009.296 kb on - strand at 1009.296 kb on - strand at 1009.328 kb on - strand at 1009.328 kb on - strand at 1009.331 kb on + strand at 1009.331 kb on + strand at 1009.331 kb on + strand at 1009.331 kb on + strand at 1009.331 kb on + strand at 1009.332 kb on - strand at 1009.332 kb on - strand at 1009.332 kb on - strand at 1009.340 kb on + strand at 1009.340 kb on + strand at 1009.340 kb on + strand at 1009.353 kb on + strand at 1009.403 kb on + strand at 1009.410 kb on - strand at 1009.449 kb on - strand at 1009.461 kb on + strand at 1009.484 kb on + strand at 1009.570 kb on - strand at 1009.571 kb on + strand at 1009.571 kb on + strand at 1009.572 kb on - strand at 1009.572 kb on - strand at 1009.572 kb on - strand at 1009.607 kb on - strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.610 kb on + strand at 1009.611 kb on - strand at 1009.611 kb on - strand at 1009.611 kb on - strand at 1009.611 kb on - strand at 1009.611 kb on - strand at 1009.611 kb on - strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.711 kb on + strand at 1009.712 kb on - strand at 1009.712 kb on - strand at 1009.712 kb on - strand at 1009.712 kb on - strand at 1009.712 kb on - strand at 1009.712 kb on - strand at 1009.715 kb on + strand at 1009.715 kb on + strand at 1009.716 kb on - strand at 1009.741 kb on + strand at 1009.741 kb on + strand at 1009.742 kb on - strand at 1009.742 kb on - strand at 1009.745 kb on + strand at 1009.757 kb on + strand at 1009.757 kb on + strand at 1009.766 kb on - strand at 1009.766 kb on - strand at 1009.766 kb on - strand at 1009.766 kb on - strand at 1009.798 kb on + strand at 1009.798 kb on + strand at 1009.798 kb on + strand at 1009.798 kb on + strand at 1009.802 kb on + strand at 1009.803 kb on - strand at 1009.826 kb on + strand at 1009.826 kb on + strand at 1009.827 kb on - strand at 1009.827 kb on - strand at 1009.827 kb on - strand at 1009.842 kb on + strand at 1009.953 kb on + strand at 1009.962 kb on + strand at 1009.962 kb on + strand at 1009.988 kb on - strand at 1009.997 kb on + strand at 1010.007 kb on + strand at 1010.041 kb on + strand at 1010.041 kb on + strand at 1010.041 kb on + strand at 1010.041 kb on + strand at 1010.042 kb on - strand at 1010.042 kb on - strand at 1010.042 kb on - strand at 1010.042 kb on - strand at 1010.042 kb on - strand at 1010.042 kb on - strand at 1010.050 kb on - strand at 1010.050 kb on - strand at 1010.050 kb on - strand at 1010.050 kb on - strand at 1010.050 kb on - strand at 1010.050 kb on - strand at 1010.070 kb on - strand at 1010.145 kb on - strand at 1010.203 kb on + strand at 1010.203 kb on + strand at 1010.204 kb on - strand at 1010.234 kb on - strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.326 kb on + strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.327 kb on - strand, within DZA65_RS04870 at 1010.328 kb on + strand, within DZA65_RS04870 at 1010.328 kb on + strand, within DZA65_RS04870 at 1010.329 kb on - strand, within DZA65_RS04870 at 1010.329 kb on - strand, within DZA65_RS04870 at 1010.329 kb on - strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.330 kb on + strand, within DZA65_RS04870 at 1010.331 kb on - strand, within DZA65_RS04870 at 1010.331 kb on - strand, within DZA65_RS04870 at 1010.331 kb on - strand, within DZA65_RS04870 at 1010.331 kb on - strand, within DZA65_RS04870 at 1010.331 kb on - strand, within DZA65_RS04870 at 1010.331 kb on - strand, within DZA65_RS04870 at 1010.349 kb on - strand, within DZA65_RS04870 at 1010.415 kb on - strand, within DZA65_RS04870 at 1010.415 kb on - strand, within DZA65_RS04870 at 1010.529 kb on + strand, within DZA65_RS04870 at 1010.554 kb on + strand, within DZA65_RS04870 at 1010.554 kb on + strand, within DZA65_RS04870 at 1010.554 kb on + strand, within DZA65_RS04870 at 1010.555 kb on - strand at 1010.555 kb on - strand, within DZA65_RS04870 at 1010.555 kb on - strand at 1010.555 kb on - strand, within DZA65_RS04870 at 1010.556 kb on + strand, within DZA65_RS04870 at 1010.557 kb on - strand, within DZA65_RS04870 at 1010.577 kb on + strand, within DZA65_RS04870 at 1010.577 kb on + strand, within DZA65_RS04870 at 1010.578 kb on - strand, within DZA65_RS04870 at 1010.578 kb on - strand, within DZA65_RS04870 at 1010.620 kb on + strand at 1010.620 kb on + strand at 1010.621 kb on - strand at 1010.628 kb on + strand at 1010.628 kb on + strand at 1010.628 kb on + strand at 1010.628 kb on + strand at 1010.629 kb on - strand at 1010.704 kb on + strand at 1010.705 kb on - strand at 1010.705 kb on - strand at 1010.705 kb on - strand at 1010.845 kb on + strand, within DZA65_RS04875 at 1010.845 kb on + strand, within DZA65_RS04875 at 1010.845 kb on + strand, within DZA65_RS04875 at 1010.845 kb on + strand, within DZA65_RS04875 at 1010.845 kb on + strand, within DZA65_RS04875 at 1010.846 kb on - strand, within DZA65_RS04875 at 1010.846 kb on - strand, within DZA65_RS04875 at 1010.846 kb on - strand, within DZA65_RS04875 at 1010.846 kb on - strand, within DZA65_RS04875 at 1010.881 kb on + strand, within DZA65_RS04875 at 1010.882 kb on - strand, within DZA65_RS04875 at 1010.882 kb on - strand, within DZA65_RS04875 at 1010.882 kb on - strand, within DZA65_RS04875 at 1010.921 kb on - strand, within DZA65_RS04875 at 1010.963 kb on + strand at 1010.963 kb on + strand at 1010.963 kb on + strand at 1010.964 kb on - strand at 1010.964 kb on - strand at 1010.964 kb on - strand at 1010.964 kb on - strand at 1010.977 kb on + strand at 1010.977 kb on + strand at 1010.977 kb on + strand at 1010.977 kb on + strand at 1010.978 kb on - strand at 1010.978 kb on - strand at 1010.978 kb on - strand at 1010.978 kb on - strand at 1010.978 kb on - strand at 1011.010 kb on + strand at 1011.010 kb on + strand at 1011.010 kb on + strand at 1011.011 kb on - strand at 1011.051 kb on + strand at 1011.051 kb on + strand at 1011.052 kb on - strand at 1011.094 kb on + strand, within DZA65_RS04880 at 1011.114 kb on + strand, within DZA65_RS04880 at 1011.196 kb on + strand, within DZA65_RS04880 at 1011.196 kb on + strand, within DZA65_RS04880 at 1011.196 kb on + strand, within DZA65_RS04880 at 1011.196 kb on + strand, within DZA65_RS04880 at 1011.197 kb on - strand, within DZA65_RS04880 at 1011.197 kb on - strand, within DZA65_RS04880 at 1011.197 kb on - strand, within DZA65_RS04880 at 1011.197 kb on - strand, within DZA65_RS04880 at 1011.240 kb on + strand, within DZA65_RS04880 at 1011.241 kb on - strand, within DZA65_RS04880 at 1011.241 kb on - strand, within DZA65_RS04880 at 1011.244 kb on + strand, within DZA65_RS04880 at 1011.244 kb on + strand, within DZA65_RS04880 at 1011.245 kb on - strand, within DZA65_RS04880 at 1011.245 kb on - strand at 1011.260 kb on + strand, within DZA65_RS04880 at 1011.260 kb on + strand, within DZA65_RS04880 at 1011.260 kb on + strand, within DZA65_RS04880 at 1011.260 kb on + strand, within DZA65_RS04880 at 1011.260 kb on + strand, within DZA65_RS04880 at 1011.261 kb on - strand, within DZA65_RS04880 at 1011.261 kb on - strand, within DZA65_RS04880 at 1011.261 kb on - strand, within DZA65_RS04880 at 1011.261 kb on - strand, within DZA65_RS04880 at 1011.261 kb on - strand at 1011.261 kb on - strand, within DZA65_RS04880 at 1011.261 kb on - strand, within DZA65_RS04880 at 1011.262 kb on + strand, within DZA65_RS04880 at 1011.262 kb on + strand, within DZA65_RS04880 at 1011.301 kb on + strand, within DZA65_RS04880 at 1011.353 kb on - strand, within DZA65_RS04880 at 1011.353 kb on - strand, within DZA65_RS04880 at 1011.565 kb on - strand at 1011.597 kb on + strand at 1011.597 kb on + strand at 1011.597 kb on + strand at 1011.597 kb on + strand at 1011.598 kb on - strand at 1011.610 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 1,009,271 + +0.9 1,009,271 + -0.3 1,009,271 + -0.7 1,009,272 - +1.2 1,009,295 + -0.0 1,009,295 + -1.1 1,009,295 + +0.6 1,009,295 + -0.2 1,009,296 - -1.1 1,009,296 - -1.0 1,009,328 - -0.6 1,009,328 - -1.2 1,009,331 + +1.8 1,009,331 + -0.8 1,009,331 + -0.3 1,009,331 + -1.0 1,009,331 + +0.7 1,009,332 - -1.4 1,009,332 - +0.1 1,009,332 - +1.3 1,009,340 + +1.0 1,009,340 + +0.0 1,009,340 + -0.1 1,009,353 + -0.7 1,009,403 + +1.0 1,009,410 - +0.8 1,009,449 - +1.0 1,009,461 + -0.1 1,009,484 + +0.4 1,009,570 - +0.0 1,009,571 + -0.5 1,009,571 + -1.4 1,009,572 - -0.5 1,009,572 - -0.5 1,009,572 - -1.3 1,009,607 - -0.0 1,009,610 + +0.2 1,009,610 + +0.0 1,009,610 + -0.8 1,009,610 + -2.2 1,009,610 + -0.6 1,009,610 + -1.3 1,009,610 + -0.2 1,009,610 + +0.1 1,009,611 - +0.2 1,009,611 - +0.5 1,009,611 - -1.0 1,009,611 - -0.6 1,009,611 - -0.8 1,009,611 - -0.9 1,009,711 + +0.6 1,009,711 + +0.6 1,009,711 + +1.4 1,009,711 + -0.3 1,009,711 + -0.5 1,009,711 + -1.6 1,009,711 + -0.6 1,009,711 + -0.2 1,009,711 + +0.7 1,009,711 + -0.1 1,009,712 - -0.1 1,009,712 - +0.3 1,009,712 - -0.5 1,009,712 - -0.8 1,009,712 - -0.8 1,009,712 - -1.0 1,009,715 + -1.6 1,009,715 + +0.6 1,009,716 - +1.8 1,009,741 + +0.4 1,009,741 + -0.6 1,009,742 - -0.7 1,009,742 - -0.1 1,009,745 + +0.3 1,009,757 + -1.6 1,009,757 + +0.3 1,009,766 - -1.0 1,009,766 - +0.2 1,009,766 - -0.2 1,009,766 - -0.4 1,009,798 + -1.3 1,009,798 + -0.7 1,009,798 + -0.3 1,009,798 + -1.1 1,009,802 + +0.4 1,009,803 - -1.6 1,009,826 + -0.2 1,009,826 + +0.3 1,009,827 - +0.6 1,009,827 - -0.7 1,009,827 - -2.1 1,009,842 + +0.2 1,009,953 + -0.8 1,009,962 + +0.0 1,009,962 + -0.3 1,009,988 - -0.8 1,009,997 + +0.3 1,010,007 + -1.6 1,010,041 + +1.0 1,010,041 + -0.5 1,010,041 + -1.6 1,010,041 + -0.4 1,010,042 - -0.3 1,010,042 - +1.8 1,010,042 - +1.0 1,010,042 - +0.3 1,010,042 - +0.3 1,010,042 - -0.6 1,010,050 - -0.5 1,010,050 - +0.0 1,010,050 - -0.3 1,010,050 - -0.1 1,010,050 - -1.1 1,010,050 - -0.6 1,010,070 - +1.4 1,010,145 - +1.0 1,010,203 + +0.0 1,010,203 + +0.3 1,010,204 - -1.2 1,010,234 - DZA65_RS04870 0.15 -1.1 1,010,326 + DZA65_RS04870 0.34 +0.5 1,010,326 + DZA65_RS04870 0.34 +0.6 1,010,326 + DZA65_RS04870 0.34 +0.6 1,010,326 + DZA65_RS04870 0.34 -1.4 1,010,326 + DZA65_RS04870 0.34 +1.3 1,010,326 + DZA65_RS04870 0.34 +0.4 1,010,326 + DZA65_RS04870 0.34 +0.3 1,010,326 + DZA65_RS04870 0.34 +0.0 1,010,326 + DZA65_RS04870 0.34 +1.4 1,010,327 - DZA65_RS04870 0.35 +1.3 1,010,327 - DZA65_RS04870 0.35 -0.6 1,010,327 - DZA65_RS04870 0.35 +1.0 1,010,327 - DZA65_RS04870 0.35 +1.6 1,010,327 - DZA65_RS04870 0.35 -0.1 1,010,327 - DZA65_RS04870 0.35 +0.0 1,010,327 - DZA65_RS04870 0.35 -1.3 1,010,328 + DZA65_RS04870 0.35 +0.1 1,010,328 + DZA65_RS04870 0.35 +0.0 1,010,329 - DZA65_RS04870 0.35 -0.6 1,010,329 - DZA65_RS04870 0.35 +1.0 1,010,329 - DZA65_RS04870 0.35 +0.2 1,010,330 + DZA65_RS04870 0.35 +0.3 1,010,330 + DZA65_RS04870 0.35 -1.0 1,010,330 + DZA65_RS04870 0.35 -0.1 1,010,330 + DZA65_RS04870 0.35 -1.1 1,010,330 + DZA65_RS04870 0.35 -1.0 1,010,330 + DZA65_RS04870 0.35 +1.6 1,010,330 + DZA65_RS04870 0.35 -0.3 1,010,330 + DZA65_RS04870 0.35 +1.8 1,010,331 - DZA65_RS04870 0.35 -0.6 1,010,331 - DZA65_RS04870 0.35 +0.3 1,010,331 - DZA65_RS04870 0.35 +0.7 1,010,331 - DZA65_RS04870 0.35 -0.4 1,010,331 - DZA65_RS04870 0.35 +0.2 1,010,331 - DZA65_RS04870 0.35 -1.5 1,010,349 - DZA65_RS04870 0.39 -2.1 1,010,415 - DZA65_RS04870 0.53 -0.3 1,010,415 - DZA65_RS04870 0.53 -0.9 1,010,529 + DZA65_RS04870 0.77 +1.0 1,010,554 + DZA65_RS04870 0.82 +1.3 1,010,554 + DZA65_RS04870 0.82 +0.0 1,010,554 + DZA65_RS04870 0.82 +0.1 1,010,555 - -1.0 1,010,555 - DZA65_RS04870 0.82 -0.8 1,010,555 - -0.6 1,010,555 - DZA65_RS04870 0.82 +1.0 1,010,556 + DZA65_RS04870 0.82 -0.3 1,010,557 - DZA65_RS04870 0.82 -0.6 1,010,577 + DZA65_RS04870 0.87 +0.2 1,010,577 + DZA65_RS04870 0.87 -0.3 1,010,578 - DZA65_RS04870 0.87 -1.5 1,010,578 - DZA65_RS04870 0.87 +0.3 1,010,620 + -2.1 1,010,620 + -1.6 1,010,621 - +0.2 1,010,628 + -0.5 1,010,628 + -1.4 1,010,628 + -1.2 1,010,628 + +0.3 1,010,629 - +0.2 1,010,704 + -0.6 1,010,705 - -0.4 1,010,705 - +0.0 1,010,705 - -0.4 1,010,845 + DZA65_RS04875 0.55 -1.4 1,010,845 + DZA65_RS04875 0.55 +0.0 1,010,845 + DZA65_RS04875 0.55 +0.4 1,010,845 + DZA65_RS04875 0.55 -0.3 1,010,845 + DZA65_RS04875 0.55 -0.3 1,010,846 - DZA65_RS04875 0.55 +0.8 1,010,846 - DZA65_RS04875 0.55 -0.3 1,010,846 - DZA65_RS04875 0.55 -0.1 1,010,846 - DZA65_RS04875 0.55 +0.6 1,010,881 + DZA65_RS04875 0.71 +0.2 1,010,882 - DZA65_RS04875 0.71 +0.7 1,010,882 - DZA65_RS04875 0.71 -2.6 1,010,882 - DZA65_RS04875 0.71 +1.3 1,010,921 - DZA65_RS04875 0.88 +0.6 1,010,963 + +0.0 1,010,963 + +1.0 1,010,963 + -1.3 1,010,964 - -0.5 1,010,964 - -0.3 1,010,964 - -0.4 1,010,964 - -2.0 1,010,977 + +0.4 1,010,977 + -0.8 1,010,977 + +0.1 1,010,977 + -0.8 1,010,978 - +0.7 1,010,978 - -1.8 1,010,978 - -0.3 1,010,978 - -0.7 1,010,978 - -0.8 1,011,010 + -0.9 1,011,010 + +0.4 1,011,010 + +0.3 1,011,011 - +0.0 1,011,051 + -0.5 1,011,051 + -0.8 1,011,052 - +1.4 1,011,094 + DZA65_RS04880 0.14 -1.3 1,011,114 + DZA65_RS04880 0.18 -1.4 1,011,196 + DZA65_RS04880 0.35 -0.4 1,011,196 + DZA65_RS04880 0.35 +0.2 1,011,196 + DZA65_RS04880 0.35 +1.8 1,011,196 + DZA65_RS04880 0.35 -0.7 1,011,197 - DZA65_RS04880 0.35 +0.8 1,011,197 - DZA65_RS04880 0.35 +0.2 1,011,197 - DZA65_RS04880 0.35 +0.1 1,011,197 - DZA65_RS04880 0.35 -1.3 1,011,240 + DZA65_RS04880 0.44 -1.0 1,011,241 - DZA65_RS04880 0.45 -0.1 1,011,241 - DZA65_RS04880 0.45 -0.4 1,011,244 + DZA65_RS04880 0.45 -0.1 1,011,244 + DZA65_RS04880 0.45 -0.4 1,011,245 - DZA65_RS04880 0.45 -0.6 1,011,245 - +1.0 1,011,260 + DZA65_RS04880 0.48 +0.5 1,011,260 + DZA65_RS04880 0.48 -0.2 1,011,260 + DZA65_RS04880 0.48 -0.9 1,011,260 + DZA65_RS04880 0.48 +0.5 1,011,260 + DZA65_RS04880 0.48 -0.0 1,011,261 - DZA65_RS04880 0.49 -0.6 1,011,261 - DZA65_RS04880 0.49 -0.1 1,011,261 - DZA65_RS04880 0.49 -0.8 1,011,261 - DZA65_RS04880 0.49 +0.2 1,011,261 - -0.3 1,011,261 - DZA65_RS04880 0.49 -0.5 1,011,261 - DZA65_RS04880 0.49 -0.4 1,011,262 + DZA65_RS04880 0.49 +0.6 1,011,262 + DZA65_RS04880 0.49 -1.3 1,011,301 + DZA65_RS04880 0.57 +0.2 1,011,353 - DZA65_RS04880 0.68 -0.5 1,011,353 - DZA65_RS04880 0.68 -0.2 1,011,565 - +0.7 1,011,597 + -0.4 1,011,597 + -0.5 1,011,597 + -0.2 1,011,597 + -0.4 1,011,598 - +0.2 1,011,610 + -0.4
Or see this region's nucleotide sequence