Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS10285 and HGI48_RS10290 are separated by 45 nucleotides HGI48_RS10290 and HGI48_RS10295 are separated by 60 nucleotides HGI48_RS10295 and HGI48_RS10300 are separated by 118 nucleotides
HGI48_RS10285: HGI48_RS10285 - DUF1315 family protein, at 2,219,572 to 2,219,847
_RS10285
HGI48_RS10290: HGI48_RS10290 - bifunctional nicotinamidase/pyrazinamidase, at 2,219,893 to 2,220,534
_RS10290
HGI48_RS10295: HGI48_RS10295 - asparaginase, at 2,220,595 to 2,221,614
_RS10295
HGI48_RS10300: HGI48_RS10300 - signal peptide peptidase SppA, at 2,221,733 to 2,223,577
_RS10300
Position (kb)
2220
2221
2222 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 2219.598 kb on + strand at 2219.706 kb on + strand, within HGI48_RS10285 at 2219.706 kb on + strand, within HGI48_RS10285 at 2219.707 kb on - strand, within HGI48_RS10285 at 2219.707 kb on - strand, within HGI48_RS10285 at 2219.728 kb on - strand, within HGI48_RS10285 at 2219.817 kb on + strand, within HGI48_RS10285 at 2219.817 kb on + strand, within HGI48_RS10285 at 2219.817 kb on + strand, within HGI48_RS10285 at 2219.817 kb on + strand, within HGI48_RS10285 at 2219.818 kb on - strand, within HGI48_RS10285 at 2219.820 kb on + strand at 2219.820 kb on + strand at 2219.820 kb on + strand at 2219.821 kb on - strand at 2219.821 kb on - strand at 2219.821 kb on - strand at 2219.821 kb on - strand at 2219.845 kb on + strand at 2219.887 kb on + strand at 2219.888 kb on - strand at 2219.894 kb on + strand at 2219.895 kb on - strand at 2219.913 kb on + strand at 2219.913 kb on + strand at 2220.019 kb on + strand, within HGI48_RS10290 at 2220.019 kb on + strand, within HGI48_RS10290 at 2220.019 kb on + strand, within HGI48_RS10290 at 2220.020 kb on - strand, within HGI48_RS10290 at 2220.060 kb on + strand, within HGI48_RS10290 at 2220.062 kb on + strand, within HGI48_RS10290 at 2220.062 kb on + strand, within HGI48_RS10290 at 2220.063 kb on - strand, within HGI48_RS10290 at 2220.063 kb on - strand, within HGI48_RS10290 at 2220.134 kb on + strand, within HGI48_RS10290 at 2220.134 kb on + strand, within HGI48_RS10290 at 2220.135 kb on - strand, within HGI48_RS10290 at 2220.135 kb on - strand, within HGI48_RS10290 at 2220.150 kb on + strand, within HGI48_RS10290 at 2220.180 kb on - strand, within HGI48_RS10290 at 2220.223 kb on + strand, within HGI48_RS10290 at 2220.275 kb on - strand, within HGI48_RS10290 at 2220.517 kb on + strand at 2220.535 kb on - strand at 2220.548 kb on + strand at 2220.548 kb on + strand at 2220.548 kb on + strand at 2220.548 kb on + strand at 2220.548 kb on + strand at 2220.549 kb on - strand at 2220.549 kb on - strand at 2220.549 kb on - strand at 2220.560 kb on + strand at 2220.596 kb on + strand at 2220.596 kb on + strand at 2220.597 kb on - strand at 2220.679 kb on + strand at 2220.679 kb on + strand at 2220.680 kb on - strand at 2220.683 kb on + strand at 2220.683 kb on + strand at 2220.684 kb on - strand at 2220.717 kb on + strand, within HGI48_RS10295 at 2220.717 kb on + strand, within HGI48_RS10295 at 2220.718 kb on - strand, within HGI48_RS10295 at 2220.811 kb on - strand, within HGI48_RS10295 at 2220.815 kb on - strand, within HGI48_RS10295 at 2220.890 kb on + strand, within HGI48_RS10295 at 2220.890 kb on + strand, within HGI48_RS10295 at 2220.973 kb on + strand at 2220.974 kb on - strand, within HGI48_RS10295 at 2221.090 kb on - strand, within HGI48_RS10295 at 2221.205 kb on + strand, within HGI48_RS10295 at 2221.205 kb on + strand, within HGI48_RS10295 at 2221.206 kb on - strand, within HGI48_RS10295 at 2221.370 kb on + strand at 2221.370 kb on + strand, within HGI48_RS10295 at 2221.380 kb on - strand, within HGI48_RS10295 at 2221.450 kb on + strand at 2221.451 kb on - strand, within HGI48_RS10295 at 2221.451 kb on - strand, within HGI48_RS10295 at 2221.454 kb on + strand, within HGI48_RS10295 at 2221.454 kb on + strand, within HGI48_RS10295 at 2221.454 kb on + strand at 2221.455 kb on - strand, within HGI48_RS10295 at 2221.455 kb on - strand, within HGI48_RS10295 at 2221.455 kb on - strand, within HGI48_RS10295 at 2221.455 kb on - strand, within HGI48_RS10295 at 2221.455 kb on - strand at 2221.455 kb on - strand, within HGI48_RS10295 at 2221.544 kb on + strand at 2221.545 kb on - strand at 2221.586 kb on + strand at 2221.586 kb on + strand at 2221.586 kb on + strand at 2221.595 kb on + strand at 2221.596 kb on - strand at 2221.618 kb on + strand at 2221.618 kb on + strand at 2221.676 kb on - strand at 2221.677 kb on + strand at 2221.936 kb on - strand, within HGI48_RS10300 at 2221.950 kb on + strand, within HGI48_RS10300 at 2221.951 kb on - strand, within HGI48_RS10300 at 2222.119 kb on + strand, within HGI48_RS10300 at 2222.120 kb on - strand, within HGI48_RS10300 at 2222.230 kb on + strand, within HGI48_RS10300 at 2222.231 kb on - strand, within HGI48_RS10300 at 2222.234 kb on + strand at 2222.234 kb on + strand, within HGI48_RS10300 at 2222.234 kb on + strand, within HGI48_RS10300 at 2222.234 kb on + strand, within HGI48_RS10300 at 2222.235 kb on - strand, within HGI48_RS10300 at 2222.235 kb on - strand, within HGI48_RS10300 at 2222.235 kb on - strand, within HGI48_RS10300 at 2222.235 kb on - strand, within HGI48_RS10300 at 2222.235 kb on - strand, within HGI48_RS10300 at 2222.235 kb on - strand, within HGI48_RS10300 at 2222.242 kb on + strand, within HGI48_RS10300 at 2222.378 kb on - strand, within HGI48_RS10300 at 2222.378 kb on - strand, within HGI48_RS10300 at 2222.384 kb on + strand, within HGI48_RS10300 at 2222.385 kb on - strand, within HGI48_RS10300 at 2222.547 kb on + strand, within HGI48_RS10300 at 2222.548 kb on - strand, within HGI48_RS10300 at 2222.548 kb on - strand, within HGI48_RS10300
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 2,219,598 + +0.1 2,219,706 + HGI48_RS10285 0.49 -1.0 2,219,706 + HGI48_RS10285 0.49 +0.0 2,219,707 - HGI48_RS10285 0.49 +0.1 2,219,707 - HGI48_RS10285 0.49 -3.8 2,219,728 - HGI48_RS10285 0.57 -0.2 2,219,817 + HGI48_RS10285 0.89 -0.2 2,219,817 + HGI48_RS10285 0.89 +0.6 2,219,817 + HGI48_RS10285 0.89 +0.6 2,219,817 + HGI48_RS10285 0.89 +0.1 2,219,818 - HGI48_RS10285 0.89 -0.7 2,219,820 + +0.9 2,219,820 + -3.2 2,219,820 + -0.2 2,219,821 - +0.4 2,219,821 - -1.2 2,219,821 - -1.2 2,219,821 - +1.2 2,219,845 + +1.2 2,219,887 + -0.6 2,219,888 - +1.0 2,219,894 + -1.7 2,219,895 - +0.4 2,219,913 + -0.9 2,219,913 + +2.0 2,220,019 + HGI48_RS10290 0.20 +1.6 2,220,019 + HGI48_RS10290 0.20 +1.0 2,220,019 + HGI48_RS10290 0.20 -0.8 2,220,020 - HGI48_RS10290 0.20 -1.4 2,220,060 + HGI48_RS10290 0.26 -0.4 2,220,062 + HGI48_RS10290 0.26 +0.2 2,220,062 + HGI48_RS10290 0.26 -0.9 2,220,063 - HGI48_RS10290 0.26 +0.0 2,220,063 - HGI48_RS10290 0.26 +0.1 2,220,134 + HGI48_RS10290 0.38 -0.3 2,220,134 + HGI48_RS10290 0.38 +1.5 2,220,135 - HGI48_RS10290 0.38 +0.6 2,220,135 - HGI48_RS10290 0.38 +0.2 2,220,150 + HGI48_RS10290 0.40 -1.6 2,220,180 - HGI48_RS10290 0.45 +0.2 2,220,223 + HGI48_RS10290 0.51 +0.6 2,220,275 - HGI48_RS10290 0.60 +0.4 2,220,517 + +1.1 2,220,535 - +0.4 2,220,548 + +0.8 2,220,548 + +0.8 2,220,548 + -0.1 2,220,548 + +0.7 2,220,548 + +0.1 2,220,549 - -0.2 2,220,549 - -0.1 2,220,549 - +0.0 2,220,560 + -1.9 2,220,596 + +1.0 2,220,596 + +0.2 2,220,597 - -0.3 2,220,679 + -0.1 2,220,679 + +0.6 2,220,680 - -0.3 2,220,683 + -1.2 2,220,683 + -0.2 2,220,684 - -1.2 2,220,717 + HGI48_RS10295 0.12 -0.2 2,220,717 + HGI48_RS10295 0.12 +0.1 2,220,718 - HGI48_RS10295 0.12 +0.9 2,220,811 - HGI48_RS10295 0.21 -0.1 2,220,815 - HGI48_RS10295 0.22 -0.5 2,220,890 + HGI48_RS10295 0.29 +0.4 2,220,890 + HGI48_RS10295 0.29 +0.4 2,220,973 + -1.2 2,220,974 - HGI48_RS10295 0.37 -0.7 2,221,090 - HGI48_RS10295 0.49 +1.2 2,221,205 + HGI48_RS10295 0.60 +0.7 2,221,205 + HGI48_RS10295 0.60 +0.6 2,221,206 - HGI48_RS10295 0.60 -0.2 2,221,370 + +1.4 2,221,370 + HGI48_RS10295 0.76 -0.6 2,221,380 - HGI48_RS10295 0.77 -0.4 2,221,450 + -1.2 2,221,451 - HGI48_RS10295 0.84 +0.6 2,221,451 - HGI48_RS10295 0.84 +1.4 2,221,454 + HGI48_RS10295 0.84 -0.8 2,221,454 + HGI48_RS10295 0.84 -2.2 2,221,454 + -0.2 2,221,455 - HGI48_RS10295 0.84 -1.3 2,221,455 - HGI48_RS10295 0.84 -0.2 2,221,455 - HGI48_RS10295 0.84 -0.2 2,221,455 - HGI48_RS10295 0.84 -3.2 2,221,455 - +1.4 2,221,455 - HGI48_RS10295 0.84 -0.6 2,221,544 + -1.2 2,221,545 - +0.0 2,221,586 + +2.8 2,221,586 + +0.4 2,221,586 + +0.1 2,221,595 + -0.2 2,221,596 - -0.2 2,221,618 + +1.1 2,221,618 + -0.2 2,221,676 - -1.6 2,221,677 + -1.9 2,221,936 - HGI48_RS10300 0.11 -0.7 2,221,950 + HGI48_RS10300 0.12 -1.6 2,221,951 - HGI48_RS10300 0.12 -0.2 2,222,119 + HGI48_RS10300 0.21 -2.7 2,222,120 - HGI48_RS10300 0.21 -0.0 2,222,230 + HGI48_RS10300 0.27 -0.8 2,222,231 - HGI48_RS10300 0.27 -1.1 2,222,234 + +1.4 2,222,234 + HGI48_RS10300 0.27 -0.4 2,222,234 + HGI48_RS10300 0.27 +0.4 2,222,234 + HGI48_RS10300 0.27 -2.7 2,222,235 - HGI48_RS10300 0.27 +0.9 2,222,235 - HGI48_RS10300 0.27 +1.1 2,222,235 - HGI48_RS10300 0.27 -1.9 2,222,235 - HGI48_RS10300 0.27 -0.2 2,222,235 - HGI48_RS10300 0.27 -1.6 2,222,235 - HGI48_RS10300 0.27 -0.7 2,222,242 + HGI48_RS10300 0.28 -1.6 2,222,378 - HGI48_RS10300 0.35 -0.1 2,222,378 - HGI48_RS10300 0.35 +1.1 2,222,384 + HGI48_RS10300 0.35 -0.0 2,222,385 - HGI48_RS10300 0.35 -0.6 2,222,547 + HGI48_RS10300 0.44 +1.6 2,222,548 - HGI48_RS10300 0.44 -1.4 2,222,548 - HGI48_RS10300 0.44 -0.2
Or see this region's nucleotide sequence