Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS19540 and HGI48_RS19545 are separated by 134 nucleotides HGI48_RS19545 and HGI48_RS19550 are separated by 82 nucleotides HGI48_RS19550 and HGI48_RS19555 are separated by 133 nucleotides HGI48_RS19555 and HGI48_RS19560 are separated by 17 nucleotides HGI48_RS19560 and HGI48_RS19565 are separated by 388 nucleotides
HGI48_RS19540: HGI48_RS19540 - LysE family translocator, at 4,364,396 to 4,365,001
_RS19540
HGI48_RS19545: HGI48_RS19545 - hydrolase, at 4,365,136 to 4,365,249
_RS19545
HGI48_RS19550: HGI48_RS19550 - YheU family protein, at 4,365,332 to 4,365,562
_RS19550
HGI48_RS19555: HGI48_RS19555 - phosphoribulokinase, at 4,365,696 to 4,366,565
_RS19555
HGI48_RS19560: HGI48_RS19560 - OsmC family protein, at 4,366,583 to 4,367,020
_RS19560
HGI48_RS19565: HGI48_RS19565 - cAMP-activated global transcriptional regulator CRP, at 4,367,409 to 4,368,041
_RS19565
Position (kb) 4365
4366
4367 Strain fitness (log2 ratio) -2
-1
0
1
2 at 4364.715 kb on + strand at 4364.715 kb on + strand, within HGI48_RS19540 at 4364.715 kb on + strand, within HGI48_RS19540 at 4364.715 kb on + strand, within HGI48_RS19540 at 4364.754 kb on + strand, within HGI48_RS19540 at 4364.754 kb on + strand, within HGI48_RS19540 at 4364.754 kb on + strand, within HGI48_RS19540 at 4364.754 kb on + strand, within HGI48_RS19540 at 4364.755 kb on - strand, within HGI48_RS19540 at 4364.755 kb on - strand, within HGI48_RS19540 at 4364.755 kb on - strand at 4364.755 kb on - strand at 4364.755 kb on - strand at 4364.881 kb on + strand, within HGI48_RS19540 at 4364.881 kb on + strand, within HGI48_RS19540 at 4364.881 kb on + strand, within HGI48_RS19540 at 4364.882 kb on - strand, within HGI48_RS19540 at 4364.882 kb on - strand, within HGI48_RS19540 at 4364.891 kb on + strand, within HGI48_RS19540 at 4364.892 kb on - strand, within HGI48_RS19540 at 4364.921 kb on + strand, within HGI48_RS19540 at 4364.921 kb on + strand, within HGI48_RS19540 at 4364.921 kb on + strand at 4364.921 kb on + strand, within HGI48_RS19540 at 4364.921 kb on + strand, within HGI48_RS19540 at 4364.921 kb on + strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.922 kb on - strand, within HGI48_RS19540 at 4364.926 kb on + strand, within HGI48_RS19540 at 4364.926 kb on + strand, within HGI48_RS19540 at 4364.926 kb on + strand, within HGI48_RS19540 at 4364.926 kb on + strand, within HGI48_RS19540 at 4364.926 kb on + strand, within HGI48_RS19540 at 4364.927 kb on - strand, within HGI48_RS19540 at 4364.927 kb on - strand, within HGI48_RS19540 at 4364.927 kb on - strand, within HGI48_RS19540 at 4364.927 kb on - strand at 4364.927 kb on - strand, within HGI48_RS19540 at 4364.927 kb on - strand at 4364.927 kb on - strand, within HGI48_RS19540 at 4364.927 kb on - strand, within HGI48_RS19540 at 4364.929 kb on + strand, within HGI48_RS19540 at 4364.930 kb on - strand, within HGI48_RS19540 at 4364.930 kb on - strand, within HGI48_RS19540 at 4364.930 kb on - strand, within HGI48_RS19540 at 4365.039 kb on + strand at 4365.039 kb on + strand at 4365.039 kb on + strand at 4365.040 kb on - strand at 4365.040 kb on - strand at 4365.052 kb on + strand at 4365.052 kb on + strand at 4365.053 kb on - strand at 4365.073 kb on + strand at 4365.074 kb on - strand at 4365.142 kb on - strand at 4365.157 kb on - strand, within HGI48_RS19545 at 4365.157 kb on - strand, within HGI48_RS19545 at 4365.245 kb on + strand at 4365.245 kb on + strand at 4365.245 kb on + strand at 4365.245 kb on + strand at 4365.246 kb on - strand at 4365.246 kb on - strand at 4365.293 kb on - strand at 4365.307 kb on + strand at 4365.315 kb on + strand at 4365.316 kb on - strand at 4365.414 kb on - strand, within HGI48_RS19550 at 4365.454 kb on + strand, within HGI48_RS19550 at 4365.454 kb on + strand, within HGI48_RS19550 at 4365.455 kb on - strand, within HGI48_RS19550 at 4365.456 kb on + strand, within HGI48_RS19550 at 4365.456 kb on + strand, within HGI48_RS19550 at 4365.456 kb on + strand, within HGI48_RS19550 at 4365.456 kb on + strand, within HGI48_RS19550 at 4365.456 kb on + strand, within HGI48_RS19550 at 4365.457 kb on - strand, within HGI48_RS19550 at 4365.457 kb on - strand, within HGI48_RS19550 at 4365.457 kb on - strand, within HGI48_RS19550 at 4365.457 kb on - strand, within HGI48_RS19550 at 4365.457 kb on - strand, within HGI48_RS19550 at 4365.457 kb on - strand, within HGI48_RS19550 at 4365.520 kb on + strand, within HGI48_RS19550 at 4365.558 kb on - strand at 4365.558 kb on - strand at 4365.558 kb on - strand at 4365.558 kb on - strand at 4365.560 kb on + strand at 4365.579 kb on + strand at 4365.588 kb on - strand at 4365.609 kb on - strand at 4365.610 kb on + strand at 4365.619 kb on + strand at 4365.825 kb on + strand, within HGI48_RS19555 at 4365.825 kb on + strand, within HGI48_RS19555 at 4365.825 kb on + strand, within HGI48_RS19555 at 4365.825 kb on + strand, within HGI48_RS19555 at 4365.897 kb on + strand, within HGI48_RS19555 at 4365.898 kb on - strand, within HGI48_RS19555 at 4365.944 kb on + strand, within HGI48_RS19555 at 4365.985 kb on - strand, within HGI48_RS19555 at 4365.997 kb on - strand, within HGI48_RS19555 at 4366.014 kb on + strand, within HGI48_RS19555 at 4366.080 kb on + strand, within HGI48_RS19555 at 4366.263 kb on + strand, within HGI48_RS19555 at 4366.263 kb on + strand, within HGI48_RS19555 at 4366.263 kb on + strand, within HGI48_RS19555 at 4366.264 kb on - strand, within HGI48_RS19555 at 4366.264 kb on - strand, within HGI48_RS19555 at 4366.272 kb on + strand, within HGI48_RS19555 at 4366.272 kb on + strand, within HGI48_RS19555 at 4366.272 kb on + strand, within HGI48_RS19555 at 4366.272 kb on + strand, within HGI48_RS19555 at 4366.272 kb on + strand, within HGI48_RS19555 at 4366.272 kb on + strand, within HGI48_RS19555 at 4366.272 kb on + strand at 4366.272 kb on + strand at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.273 kb on - strand, within HGI48_RS19555 at 4366.327 kb on + strand, within HGI48_RS19555 at 4366.515 kb on - strand at 4366.550 kb on + strand at 4366.550 kb on + strand at 4366.550 kb on + strand at 4366.550 kb on + strand at 4366.557 kb on - strand at 4366.557 kb on - strand at 4366.564 kb on - strand at 4366.656 kb on + strand, within HGI48_RS19560 at 4366.656 kb on + strand at 4366.656 kb on + strand, within HGI48_RS19560 at 4366.657 kb on - strand, within HGI48_RS19560 at 4366.753 kb on + strand, within HGI48_RS19560 at 4366.753 kb on + strand, within HGI48_RS19560 at 4366.754 kb on - strand, within HGI48_RS19560 at 4366.754 kb on - strand, within HGI48_RS19560 at 4366.754 kb on - strand, within HGI48_RS19560 at 4366.754 kb on - strand, within HGI48_RS19560 at 4366.754 kb on - strand, within HGI48_RS19560 at 4366.840 kb on - strand, within HGI48_RS19560 at 4367.020 kb on + strand at 4367.021 kb on - strand at 4367.021 kb on - strand at 4367.021 kb on - strand at 4367.021 kb on - strand at 4367.021 kb on - strand at 4367.041 kb on - strand at 4367.055 kb on - strand at 4367.083 kb on - strand at 4367.093 kb on + strand at 4367.093 kb on + strand at 4367.094 kb on - strand at 4367.094 kb on - strand at 4367.094 kb on - strand at 4367.094 kb on - strand at 4367.094 kb on - strand at 4367.125 kb on + strand at 4367.125 kb on + strand at 4367.125 kb on + strand at 4367.141 kb on + strand at 4367.155 kb on + strand at 4367.216 kb on + strand at 4367.278 kb on - strand at 4367.292 kb on + strand at 4367.292 kb on + strand at 4367.331 kb on + strand at 4367.335 kb on + strand at 4367.335 kb on + strand at 4367.335 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 4,364,715 + +0.2 4,364,715 + HGI48_RS19540 0.53 -1.5 4,364,715 + HGI48_RS19540 0.53 -0.1 4,364,715 + HGI48_RS19540 0.53 +1.6 4,364,754 + HGI48_RS19540 0.59 -0.1 4,364,754 + HGI48_RS19540 0.59 -0.8 4,364,754 + HGI48_RS19540 0.59 -0.3 4,364,754 + HGI48_RS19540 0.59 +1.6 4,364,755 - HGI48_RS19540 0.59 +1.0 4,364,755 - HGI48_RS19540 0.59 -0.8 4,364,755 - -0.4 4,364,755 - +1.2 4,364,755 - -0.4 4,364,881 + HGI48_RS19540 0.80 -0.3 4,364,881 + HGI48_RS19540 0.80 -1.8 4,364,881 + HGI48_RS19540 0.80 +0.2 4,364,882 - HGI48_RS19540 0.80 +0.2 4,364,882 - HGI48_RS19540 0.80 +1.4 4,364,891 + HGI48_RS19540 0.82 +0.9 4,364,892 - HGI48_RS19540 0.82 +0.5 4,364,921 + HGI48_RS19540 0.87 -0.3 4,364,921 + HGI48_RS19540 0.87 +0.2 4,364,921 + +0.6 4,364,921 + HGI48_RS19540 0.87 +0.4 4,364,921 + HGI48_RS19540 0.87 -0.1 4,364,921 + HGI48_RS19540 0.87 -0.5 4,364,922 - HGI48_RS19540 0.87 -0.8 4,364,922 - HGI48_RS19540 0.87 +0.2 4,364,922 - HGI48_RS19540 0.87 +0.2 4,364,922 - HGI48_RS19540 0.87 +1.2 4,364,922 - HGI48_RS19540 0.87 +0.7 4,364,922 - HGI48_RS19540 0.87 +2.0 4,364,922 - HGI48_RS19540 0.87 +1.5 4,364,922 - HGI48_RS19540 0.87 -0.8 4,364,922 - HGI48_RS19540 0.87 +0.4 4,364,922 - HGI48_RS19540 0.87 +0.2 4,364,922 - HGI48_RS19540 0.87 +1.4 4,364,922 - HGI48_RS19540 0.87 -2.0 4,364,922 - HGI48_RS19540 0.87 -1.3 4,364,926 + HGI48_RS19540 0.87 +0.2 4,364,926 + HGI48_RS19540 0.87 +0.6 4,364,926 + HGI48_RS19540 0.87 -0.9 4,364,926 + HGI48_RS19540 0.87 +0.7 4,364,926 + HGI48_RS19540 0.87 -1.1 4,364,927 - HGI48_RS19540 0.88 +0.2 4,364,927 - HGI48_RS19540 0.88 +0.9 4,364,927 - HGI48_RS19540 0.88 -1.2 4,364,927 - +2.2 4,364,927 - HGI48_RS19540 0.88 -1.7 4,364,927 - +1.2 4,364,927 - HGI48_RS19540 0.88 -2.2 4,364,927 - HGI48_RS19540 0.88 -1.4 4,364,929 + HGI48_RS19540 0.88 -1.7 4,364,930 - HGI48_RS19540 0.88 +1.6 4,364,930 - HGI48_RS19540 0.88 +2.0 4,364,930 - HGI48_RS19540 0.88 -1.4 4,365,039 + -1.4 4,365,039 + +2.2 4,365,039 + -1.2 4,365,040 - +1.0 4,365,040 - +0.5 4,365,052 + -0.9 4,365,052 + -0.8 4,365,053 - -0.8 4,365,073 + -1.3 4,365,074 - -1.5 4,365,142 - +0.8 4,365,157 - HGI48_RS19545 0.18 +0.5 4,365,157 - HGI48_RS19545 0.18 -2.2 4,365,245 + -1.5 4,365,245 + -1.4 4,365,245 + -1.4 4,365,245 + +2.4 4,365,246 - +0.0 4,365,246 - +0.3 4,365,293 - -0.8 4,365,307 + +0.3 4,365,315 + -1.5 4,365,316 - +0.3 4,365,414 - HGI48_RS19550 0.35 +0.6 4,365,454 + HGI48_RS19550 0.53 +0.9 4,365,454 + HGI48_RS19550 0.53 -0.2 4,365,455 - HGI48_RS19550 0.53 -1.4 4,365,456 + HGI48_RS19550 0.54 +0.2 4,365,456 + HGI48_RS19550 0.54 +0.6 4,365,456 + HGI48_RS19550 0.54 +0.6 4,365,456 + HGI48_RS19550 0.54 -0.0 4,365,456 + HGI48_RS19550 0.54 +0.1 4,365,457 - HGI48_RS19550 0.54 +1.7 4,365,457 - HGI48_RS19550 0.54 +0.2 4,365,457 - HGI48_RS19550 0.54 -1.0 4,365,457 - HGI48_RS19550 0.54 -0.4 4,365,457 - HGI48_RS19550 0.54 -0.7 4,365,457 - HGI48_RS19550 0.54 +0.2 4,365,520 + HGI48_RS19550 0.81 -1.0 4,365,558 - -0.8 4,365,558 - +1.2 4,365,558 - +1.0 4,365,558 - +0.2 4,365,560 + -0.2 4,365,579 + -0.7 4,365,588 - +0.8 4,365,609 - +0.2 4,365,610 + +0.1 4,365,619 + -1.0 4,365,825 + HGI48_RS19555 0.15 -0.3 4,365,825 + HGI48_RS19555 0.15 +1.4 4,365,825 + HGI48_RS19555 0.15 -0.3 4,365,825 + HGI48_RS19555 0.15 -0.1 4,365,897 + HGI48_RS19555 0.23 -0.0 4,365,898 - HGI48_RS19555 0.23 +1.5 4,365,944 + HGI48_RS19555 0.29 -0.4 4,365,985 - HGI48_RS19555 0.33 +0.8 4,365,997 - HGI48_RS19555 0.35 +0.3 4,366,014 + HGI48_RS19555 0.37 +0.3 4,366,080 + HGI48_RS19555 0.44 -1.3 4,366,263 + HGI48_RS19555 0.65 -0.7 4,366,263 + HGI48_RS19555 0.65 -0.2 4,366,263 + HGI48_RS19555 0.65 -0.4 4,366,264 - HGI48_RS19555 0.65 -1.2 4,366,264 - HGI48_RS19555 0.65 +0.0 4,366,272 + HGI48_RS19555 0.66 -1.7 4,366,272 + HGI48_RS19555 0.66 -0.8 4,366,272 + HGI48_RS19555 0.66 +0.3 4,366,272 + HGI48_RS19555 0.66 -0.1 4,366,272 + HGI48_RS19555 0.66 -0.2 4,366,272 + HGI48_RS19555 0.66 -0.5 4,366,272 + +1.6 4,366,272 + -0.4 4,366,273 - HGI48_RS19555 0.66 -0.2 4,366,273 - HGI48_RS19555 0.66 +1.5 4,366,273 - HGI48_RS19555 0.66 -0.2 4,366,273 - HGI48_RS19555 0.66 -2.0 4,366,273 - HGI48_RS19555 0.66 +0.4 4,366,273 - HGI48_RS19555 0.66 +0.8 4,366,273 - HGI48_RS19555 0.66 +1.7 4,366,273 - HGI48_RS19555 0.66 -0.4 4,366,273 - HGI48_RS19555 0.66 -2.2 4,366,273 - HGI48_RS19555 0.66 -0.2 4,366,327 + HGI48_RS19555 0.73 -0.8 4,366,515 - -1.4 4,366,550 + +1.4 4,366,550 + -0.6 4,366,550 + -0.2 4,366,550 + -0.3 4,366,557 - -1.3 4,366,557 - +1.8 4,366,564 - -0.8 4,366,656 + HGI48_RS19560 0.17 -0.8 4,366,656 + +2.2 4,366,656 + HGI48_RS19560 0.17 -0.6 4,366,657 - HGI48_RS19560 0.17 +0.2 4,366,753 + HGI48_RS19560 0.39 +0.7 4,366,753 + HGI48_RS19560 0.39 +0.2 4,366,754 - HGI48_RS19560 0.39 -0.8 4,366,754 - HGI48_RS19560 0.39 +1.7 4,366,754 - HGI48_RS19560 0.39 -2.4 4,366,754 - HGI48_RS19560 0.39 -0.0 4,366,754 - HGI48_RS19560 0.39 -0.1 4,366,840 - HGI48_RS19560 0.59 -1.0 4,367,020 + +0.3 4,367,021 - +0.2 4,367,021 - -0.2 4,367,021 - +1.2 4,367,021 - +1.2 4,367,021 - +0.5 4,367,041 - +1.0 4,367,055 - +0.6 4,367,083 - +0.6 4,367,093 + -1.8 4,367,093 + +0.4 4,367,094 - -0.2 4,367,094 - +0.3 4,367,094 - -0.0 4,367,094 - -0.4 4,367,094 - +0.5 4,367,125 + +2.2 4,367,125 + +2.2 4,367,125 + -0.4 4,367,141 + +0.7 4,367,155 + +0.2 4,367,216 + -0.8 4,367,278 - +2.5 4,367,292 + +0.8 4,367,292 + +1.2 4,367,331 + +2.0 4,367,335 + -1.2 4,367,335 + +0.6 4,367,335 + -0.4
Or see this region's nucleotide sequence