Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS00080 and HGI48_RS00085 are separated by 103 nucleotides HGI48_RS00085 and HGI48_RS00090 are separated by 464 nucleotides HGI48_RS00090 and HGI48_RS00095 are separated by 93 nucleotides HGI48_RS00095 and HGI48_RS00100 are separated by 5 nucleotides
HGI48_RS00080: HGI48_RS00080 - hypothetical protein, at 22,311 to 23,525
_RS00080
HGI48_RS00085: HGI48_RS00085 - IS3 family transposase, at 23,629 to 23,754
_RS00085
HGI48_RS00090: HGI48_RS00090 - formyl-CoA transferase, at 24,219 to 25,466
_RS00090
HGI48_RS00095: HGI48_RS00095 - PAS domain-containing protein, at 25,560 to 25,997
_RS00095
HGI48_RS00100: HGI48_RS00100 - formyl-CoA transferase, at 26,003 to 27,280
_RS00100
Position (kb) 24
25
26 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 23.255 kb on + strand, within HGI48_RS00080 at 23.264 kb on + strand, within HGI48_RS00080 at 23.264 kb on + strand, within HGI48_RS00080 at 23.264 kb on + strand, within HGI48_RS00080 at 23.305 kb on + strand, within HGI48_RS00080 at 23.306 kb on - strand, within HGI48_RS00080 at 23.376 kb on + strand, within HGI48_RS00080 at 23.376 kb on + strand, within HGI48_RS00080 at 23.376 kb on + strand, within HGI48_RS00080 at 23.377 kb on - strand at 23.377 kb on - strand at 23.377 kb on - strand, within HGI48_RS00080 at 23.377 kb on - strand at 23.396 kb on + strand, within HGI48_RS00080 at 23.396 kb on + strand, within HGI48_RS00080 at 23.396 kb on + strand at 23.397 kb on - strand, within HGI48_RS00080 at 23.397 kb on - strand, within HGI48_RS00080 at 23.468 kb on + strand at 23.507 kb on + strand at 23.508 kb on - strand at 23.508 kb on - strand at 23.508 kb on - strand at 23.508 kb on - strand at 23.508 kb on - strand at 23.508 kb on - strand at 23.510 kb on + strand at 23.510 kb on + strand at 23.511 kb on - strand at 23.511 kb on - strand at 23.524 kb on - strand at 23.524 kb on - strand at 23.570 kb on - strand at 23.594 kb on + strand at 23.594 kb on + strand at 23.594 kb on + strand at 23.594 kb on + strand at 23.594 kb on + strand at 23.595 kb on - strand at 23.595 kb on - strand at 23.595 kb on - strand at 23.595 kb on - strand at 23.595 kb on - strand at 23.595 kb on - strand at 23.595 kb on - strand at 23.614 kb on + strand at 23.614 kb on + strand at 23.614 kb on + strand at 23.615 kb on - strand at 23.615 kb on - strand at 23.642 kb on + strand, within HGI48_RS00085 at 23.653 kb on - strand, within HGI48_RS00085 at 23.750 kb on - strand at 23.865 kb on + strand at 23.926 kb on + strand at 23.927 kb on - strand at 23.927 kb on - strand at 24.038 kb on + strand at 24.038 kb on + strand at 24.038 kb on + strand at 24.039 kb on - strand at 24.039 kb on - strand at 24.039 kb on - strand at 24.039 kb on - strand at 24.039 kb on - strand at 24.039 kb on - strand at 24.348 kb on - strand, within HGI48_RS00090 at 24.370 kb on + strand, within HGI48_RS00090 at 24.370 kb on + strand, within HGI48_RS00090 at 24.371 kb on - strand, within HGI48_RS00090 at 24.371 kb on - strand, within HGI48_RS00090 at 24.371 kb on - strand, within HGI48_RS00090 at 24.371 kb on - strand, within HGI48_RS00090 at 24.478 kb on + strand, within HGI48_RS00090 at 24.479 kb on - strand, within HGI48_RS00090 at 24.479 kb on - strand, within HGI48_RS00090 at 24.479 kb on - strand, within HGI48_RS00090 at 24.485 kb on + strand, within HGI48_RS00090 at 24.664 kb on + strand, within HGI48_RS00090 at 24.664 kb on + strand, within HGI48_RS00090 at 24.664 kb on + strand, within HGI48_RS00090 at 24.664 kb on + strand, within HGI48_RS00090 at 24.664 kb on + strand at 24.664 kb on + strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.665 kb on - strand, within HGI48_RS00090 at 24.668 kb on + strand, within HGI48_RS00090 at 24.668 kb on + strand, within HGI48_RS00090 at 24.668 kb on + strand, within HGI48_RS00090 at 24.669 kb on - strand, within HGI48_RS00090 at 24.669 kb on - strand, within HGI48_RS00090 at 24.669 kb on - strand, within HGI48_RS00090 at 24.669 kb on - strand, within HGI48_RS00090 at 24.669 kb on - strand, within HGI48_RS00090 at 24.669 kb on - strand, within HGI48_RS00090 at 24.670 kb on + strand, within HGI48_RS00090 at 24.670 kb on + strand, within HGI48_RS00090 at 24.670 kb on + strand, within HGI48_RS00090 at 24.670 kb on + strand, within HGI48_RS00090 at 24.670 kb on + strand, within HGI48_RS00090 at 24.670 kb on + strand, within HGI48_RS00090 at 24.671 kb on - strand, within HGI48_RS00090 at 24.849 kb on + strand, within HGI48_RS00090 at 24.849 kb on + strand, within HGI48_RS00090 at 24.850 kb on - strand, within HGI48_RS00090 at 24.850 kb on - strand, within HGI48_RS00090 at 24.906 kb on - strand at 24.933 kb on - strand, within HGI48_RS00090 at 24.933 kb on - strand at 24.933 kb on - strand, within HGI48_RS00090 at 25.054 kb on + strand, within HGI48_RS00090 at 25.133 kb on + strand, within HGI48_RS00090 at 25.133 kb on + strand, within HGI48_RS00090 at 25.133 kb on + strand, within HGI48_RS00090 at 25.134 kb on - strand at 25.134 kb on - strand, within HGI48_RS00090 at 25.134 kb on - strand, within HGI48_RS00090 at 25.227 kb on + strand, within HGI48_RS00090 at 25.228 kb on - strand, within HGI48_RS00090 at 25.228 kb on - strand, within HGI48_RS00090 at 25.286 kb on + strand, within HGI48_RS00090 at 25.286 kb on + strand at 25.287 kb on - strand, within HGI48_RS00090 at 25.287 kb on - strand, within HGI48_RS00090 at 25.303 kb on - strand, within HGI48_RS00090 at 25.303 kb on - strand, within HGI48_RS00090 at 25.303 kb on - strand, within HGI48_RS00090 at 25.303 kb on - strand, within HGI48_RS00090 at 25.320 kb on + strand, within HGI48_RS00090 at 25.321 kb on - strand, within HGI48_RS00090 at 25.364 kb on + strand at 25.364 kb on + strand at 25.365 kb on - strand at 25.365 kb on - strand at 25.393 kb on - strand at 25.401 kb on - strand at 25.419 kb on + strand at 25.419 kb on + strand at 25.419 kb on + strand at 25.419 kb on + strand at 25.420 kb on - strand at 25.420 kb on - strand at 25.420 kb on - strand at 25.420 kb on - strand at 25.420 kb on - strand at 25.427 kb on + strand at 25.437 kb on - strand at 25.452 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.493 kb on + strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.494 kb on - strand at 25.495 kb on + strand at 25.495 kb on + strand at 25.495 kb on + strand at 25.495 kb on + strand at 25.495 kb on + strand at 25.495 kb on + strand at 25.495 kb on + strand at 25.496 kb on - strand at 25.496 kb on - strand at 25.496 kb on - strand at 25.496 kb on - strand at 25.496 kb on - strand at 25.528 kb on + strand at 25.528 kb on + strand at 25.529 kb on - strand at 25.529 kb on - strand at 25.529 kb on - strand at 25.547 kb on - strand at 25.946 kb on + strand, within HGI48_RS00095 at 25.946 kb on + strand at 25.946 kb on + strand, within HGI48_RS00095 at 25.947 kb on - strand, within HGI48_RS00095 at 25.971 kb on + strand at 25.971 kb on + strand at 25.972 kb on - strand at 25.983 kb on + strand at 25.983 kb on + strand at 25.983 kb on + strand at 25.984 kb on - strand at 25.984 kb on - strand at 25.984 kb on - strand at 26.154 kb on + strand, within HGI48_RS00100 at 26.267 kb on - strand, within HGI48_RS00100 at 26.274 kb on + strand, within HGI48_RS00100 at 26.274 kb on + strand, within HGI48_RS00100 at 26.274 kb on + strand, within HGI48_RS00100 at 26.274 kb on + strand, within HGI48_RS00100 at 26.275 kb on - strand, within HGI48_RS00100 at 26.289 kb on + strand, within HGI48_RS00100 at 26.289 kb on + strand, within HGI48_RS00100 at 26.289 kb on + strand at 26.290 kb on - strand, within HGI48_RS00100 at 26.374 kb on + strand, within HGI48_RS00100 at 26.374 kb on + strand, within HGI48_RS00100 at 26.374 kb on + strand, within HGI48_RS00100 at 26.375 kb on - strand, within HGI48_RS00100 at 26.376 kb on + strand, within HGI48_RS00100 at 26.376 kb on + strand, within HGI48_RS00100 at 26.376 kb on + strand, within HGI48_RS00100 at 26.376 kb on + strand, within HGI48_RS00100 at 26.376 kb on + strand, within HGI48_RS00100 at 26.377 kb on - strand, within HGI48_RS00100 at 26.409 kb on - strand, within HGI48_RS00100 at 26.449 kb on + strand at 26.454 kb on + strand at 26.454 kb on + strand, within HGI48_RS00100 at 26.454 kb on + strand at 26.454 kb on + strand, within HGI48_RS00100 at 26.455 kb on - strand at 26.458 kb on + strand, within HGI48_RS00100 at 26.458 kb on + strand, within HGI48_RS00100 at 26.459 kb on - strand, within HGI48_RS00100 at 26.459 kb on - strand, within HGI48_RS00100 at 26.459 kb on - strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.460 kb on + strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100 at 26.461 kb on - strand, within HGI48_RS00100
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 23,255 + HGI48_RS00080 0.78 +1.0 23,264 + HGI48_RS00080 0.78 +0.9 23,264 + HGI48_RS00080 0.78 +0.4 23,264 + HGI48_RS00080 0.78 -0.6 23,305 + HGI48_RS00080 0.82 -2.4 23,306 - HGI48_RS00080 0.82 -1.7 23,376 + HGI48_RS00080 0.88 +0.5 23,376 + HGI48_RS00080 0.88 -0.4 23,376 + HGI48_RS00080 0.88 -0.2 23,377 - -0.3 23,377 - +1.2 23,377 - HGI48_RS00080 0.88 -0.7 23,377 - +0.7 23,396 + HGI48_RS00080 0.89 +1.4 23,396 + HGI48_RS00080 0.89 +1.3 23,396 + +3.2 23,397 - HGI48_RS00080 0.89 -2.7 23,397 - HGI48_RS00080 0.89 -1.1 23,468 + -0.4 23,507 + -0.8 23,508 - -0.1 23,508 - +1.1 23,508 - +1.7 23,508 - -1.0 23,508 - -0.3 23,508 - -0.8 23,510 + +1.1 23,510 + -0.5 23,511 - -0.7 23,511 - +0.3 23,524 - -0.0 23,524 - -1.0 23,570 - +0.5 23,594 + -1.1 23,594 + +1.0 23,594 + +0.3 23,594 + -0.3 23,594 + +1.6 23,595 - +1.3 23,595 - +0.0 23,595 - -2.1 23,595 - +1.2 23,595 - +1.9 23,595 - -0.8 23,595 - +0.7 23,614 + -0.8 23,614 + -0.4 23,614 + +0.5 23,615 - -0.3 23,615 - +0.1 23,642 + HGI48_RS00085 0.10 -0.3 23,653 - HGI48_RS00085 0.19 +0.3 23,750 - +0.7 23,865 + +0.5 23,926 + +2.3 23,927 - +0.4 23,927 - -0.2 24,038 + +0.2 24,038 + +0.0 24,038 + +0.1 24,039 - +1.1 24,039 - -0.4 24,039 - +1.7 24,039 - +1.6 24,039 - -0.1 24,039 - +0.2 24,348 - HGI48_RS00090 0.10 +0.7 24,370 + HGI48_RS00090 0.12 +0.1 24,370 + HGI48_RS00090 0.12 +1.8 24,371 - HGI48_RS00090 0.12 -0.4 24,371 - HGI48_RS00090 0.12 -1.4 24,371 - HGI48_RS00090 0.12 -0.6 24,371 - HGI48_RS00090 0.12 +1.4 24,478 + HGI48_RS00090 0.21 -0.1 24,479 - HGI48_RS00090 0.21 +1.0 24,479 - HGI48_RS00090 0.21 -2.0 24,479 - HGI48_RS00090 0.21 -2.3 24,485 + HGI48_RS00090 0.21 -1.3 24,664 + HGI48_RS00090 0.36 -0.8 24,664 + HGI48_RS00090 0.36 -0.0 24,664 + HGI48_RS00090 0.36 -0.1 24,664 + HGI48_RS00090 0.36 -2.4 24,664 + +0.7 24,664 + HGI48_RS00090 0.36 -0.5 24,665 - HGI48_RS00090 0.36 -0.8 24,665 - HGI48_RS00090 0.36 +0.6 24,665 - HGI48_RS00090 0.36 +0.2 24,665 - HGI48_RS00090 0.36 -2.0 24,665 - HGI48_RS00090 0.36 -1.1 24,665 - HGI48_RS00090 0.36 +1.5 24,665 - HGI48_RS00090 0.36 -1.6 24,665 - HGI48_RS00090 0.36 -0.2 24,668 + HGI48_RS00090 0.36 -0.5 24,668 + HGI48_RS00090 0.36 -0.8 24,668 + HGI48_RS00090 0.36 +0.5 24,669 - HGI48_RS00090 0.36 -1.6 24,669 - HGI48_RS00090 0.36 +0.6 24,669 - HGI48_RS00090 0.36 -1.6 24,669 - HGI48_RS00090 0.36 +0.7 24,669 - HGI48_RS00090 0.36 -1.3 24,669 - HGI48_RS00090 0.36 +1.1 24,670 + HGI48_RS00090 0.36 +0.7 24,670 + HGI48_RS00090 0.36 -1.8 24,670 + HGI48_RS00090 0.36 +0.4 24,670 + HGI48_RS00090 0.36 -2.4 24,670 + HGI48_RS00090 0.36 -0.3 24,670 + HGI48_RS00090 0.36 +0.1 24,671 - HGI48_RS00090 0.36 -1.3 24,849 + HGI48_RS00090 0.50 +0.3 24,849 + HGI48_RS00090 0.50 +0.9 24,850 - HGI48_RS00090 0.51 +0.2 24,850 - HGI48_RS00090 0.51 -2.3 24,906 - +2.2 24,933 - HGI48_RS00090 0.57 +0.0 24,933 - -0.3 24,933 - HGI48_RS00090 0.57 -1.3 25,054 + HGI48_RS00090 0.67 -0.8 25,133 + HGI48_RS00090 0.73 +1.2 25,133 + HGI48_RS00090 0.73 +0.4 25,133 + HGI48_RS00090 0.73 +0.2 25,134 - +0.7 25,134 - HGI48_RS00090 0.73 -0.2 25,134 - HGI48_RS00090 0.73 +0.0 25,227 + HGI48_RS00090 0.81 -0.8 25,228 - HGI48_RS00090 0.81 -1.6 25,228 - HGI48_RS00090 0.81 +1.3 25,286 + HGI48_RS00090 0.85 -0.5 25,286 + +2.7 25,287 - HGI48_RS00090 0.86 -0.3 25,287 - HGI48_RS00090 0.86 -0.4 25,303 - HGI48_RS00090 0.87 -1.6 25,303 - HGI48_RS00090 0.87 +0.2 25,303 - HGI48_RS00090 0.87 +1.0 25,303 - HGI48_RS00090 0.87 -0.6 25,320 + HGI48_RS00090 0.88 -0.5 25,321 - HGI48_RS00090 0.88 +1.1 25,364 + +1.6 25,364 + -1.0 25,365 - +0.7 25,365 - +0.1 25,393 - -1.3 25,401 - -0.7 25,419 + +0.4 25,419 + -1.8 25,419 + -0.5 25,419 + -2.6 25,420 - +0.3 25,420 - -0.4 25,420 - +2.2 25,420 - -0.5 25,420 - -1.3 25,427 + -1.3 25,437 - -0.4 25,452 + -1.4 25,493 + -0.7 25,493 + +0.0 25,493 + +0.3 25,493 + -0.1 25,493 + -0.3 25,493 + -1.5 25,493 + -1.3 25,493 + -1.8 25,493 + -1.1 25,493 + -1.6 25,493 + +0.6 25,493 + -0.3 25,493 + -0.8 25,494 - +1.4 25,494 - -2.3 25,494 - +1.0 25,494 - -1.6 25,494 - +0.4 25,494 - -1.8 25,494 - -2.3 25,494 - -1.3 25,495 + -0.6 25,495 + -0.1 25,495 + +2.6 25,495 + +2.3 25,495 + -1.6 25,495 + -2.8 25,495 + +0.3 25,496 - +0.3 25,496 - -0.3 25,496 - +0.0 25,496 - +1.1 25,496 - -0.3 25,528 + -1.8 25,528 + -0.3 25,529 - -1.6 25,529 - -0.5 25,529 - +1.2 25,547 - -0.8 25,946 + HGI48_RS00095 0.88 -0.4 25,946 + +2.5 25,946 + HGI48_RS00095 0.88 +0.7 25,947 - HGI48_RS00095 0.88 -2.1 25,971 + -0.3 25,971 + -0.1 25,972 - +0.7 25,983 + +0.5 25,983 + +2.3 25,983 + -0.7 25,984 - -1.3 25,984 - +0.1 25,984 - -0.3 26,154 + HGI48_RS00100 0.12 +0.6 26,267 - HGI48_RS00100 0.21 -0.5 26,274 + HGI48_RS00100 0.21 -1.3 26,274 + HGI48_RS00100 0.21 +0.2 26,274 + HGI48_RS00100 0.21 +0.3 26,274 + HGI48_RS00100 0.21 +0.3 26,275 - HGI48_RS00100 0.21 -1.6 26,289 + HGI48_RS00100 0.22 +0.3 26,289 + HGI48_RS00100 0.22 +0.7 26,289 + -0.3 26,290 - HGI48_RS00100 0.22 +0.2 26,374 + HGI48_RS00100 0.29 +0.2 26,374 + HGI48_RS00100 0.29 +2.3 26,374 + HGI48_RS00100 0.29 +0.6 26,375 - HGI48_RS00100 0.29 +0.3 26,376 + HGI48_RS00100 0.29 -0.3 26,376 + HGI48_RS00100 0.29 -1.5 26,376 + HGI48_RS00100 0.29 -0.1 26,376 + HGI48_RS00100 0.29 -0.7 26,376 + HGI48_RS00100 0.29 -2.1 26,377 - HGI48_RS00100 0.29 +1.1 26,409 - HGI48_RS00100 0.32 -0.6 26,449 + +1.5 26,454 + +0.2 26,454 + HGI48_RS00100 0.35 +0.1 26,454 + +0.7 26,454 + HGI48_RS00100 0.35 -0.3 26,455 - +0.7 26,458 + HGI48_RS00100 0.36 -0.0 26,458 + HGI48_RS00100 0.36 +0.6 26,459 - HGI48_RS00100 0.36 -1.6 26,459 - HGI48_RS00100 0.36 -1.0 26,459 - HGI48_RS00100 0.36 +1.1 26,460 + HGI48_RS00100 0.36 +0.3 26,460 + HGI48_RS00100 0.36 -0.1 26,460 + HGI48_RS00100 0.36 +1.4 26,460 + HGI48_RS00100 0.36 +0.5 26,460 + +1.3 26,460 + HGI48_RS00100 0.36 -1.8 26,460 + HGI48_RS00100 0.36 -0.5 26,460 + HGI48_RS00100 0.36 -1.6 26,460 + HGI48_RS00100 0.36 +1.0 26,460 + HGI48_RS00100 0.36 +0.5 26,460 + HGI48_RS00100 0.36 +0.2 26,461 - HGI48_RS00100 0.36 +0.9 26,461 - HGI48_RS00100 0.36 -0.3 26,461 - HGI48_RS00100 0.36 -0.3 26,461 - HGI48_RS00100 0.36 -2.6 26,461 - +0.2 26,461 - HGI48_RS00100 0.36 -0.8 26,461 - HGI48_RS00100 0.36 -2.7 26,461 - HGI48_RS00100 0.36 -0.7 26,461 - HGI48_RS00100 0.36 -0.3
Or see this region's nucleotide sequence