Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS20260 and HGI48_RS20265 are separated by 86 nucleotides HGI48_RS20265 and HGI48_RS20270 are separated by 91 nucleotides HGI48_RS20270 and HGI48_RS20275 are separated by 163 nucleotides
HGI48_RS20260: HGI48_RS20260 - sodium/proline symporter PutP, at 4,530,579 to 4,532,078
_RS20260
HGI48_RS20265: HGI48_RS20265 - hypothetical protein, at 4,532,165 to 4,532,566
_RS20265
HGI48_RS20270: HGI48_RS20270 - ketol-acid reductoisomerase, at 4,532,658 to 4,534,136
_RS20270
HGI48_RS20275: HGI48_RS20275 - HTH-type transcriptional activator IlvY, at 4,534,300 to 4,535,187
_RS20275
Position (kb)
4532
4533
4534
4535 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 4531.721 kb on - strand, within HGI48_RS20260 at 4531.789 kb on - strand, within HGI48_RS20260 at 4531.789 kb on - strand, within HGI48_RS20260 at 4531.909 kb on + strand, within HGI48_RS20260 at 4531.909 kb on + strand, within HGI48_RS20260 at 4531.909 kb on + strand, within HGI48_RS20260 at 4531.909 kb on + strand, within HGI48_RS20260 at 4531.920 kb on + strand, within HGI48_RS20260 at 4532.055 kb on - strand at 4532.096 kb on - strand at 4532.096 kb on - strand at 4532.104 kb on - strand at 4532.109 kb on + strand at 4532.109 kb on + strand at 4532.109 kb on + strand at 4532.109 kb on + strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.110 kb on - strand at 4532.119 kb on + strand at 4532.120 kb on - strand at 4532.120 kb on - strand at 4532.120 kb on - strand at 4532.135 kb on + strand at 4532.136 kb on - strand at 4532.136 kb on - strand at 4532.136 kb on - strand at 4532.136 kb on - strand at 4532.138 kb on + strand at 4532.138 kb on + strand at 4532.138 kb on + strand at 4532.139 kb on - strand at 4532.139 kb on - strand at 4532.139 kb on - strand at 4532.139 kb on - strand at 4532.139 kb on - strand at 4532.141 kb on + strand at 4532.142 kb on - strand at 4532.164 kb on - strand at 4532.205 kb on + strand at 4532.205 kb on + strand at 4532.206 kb on - strand at 4532.242 kb on - strand at 4532.285 kb on - strand, within HGI48_RS20265 at 4532.353 kb on + strand, within HGI48_RS20265 at 4532.354 kb on - strand at 4532.356 kb on - strand, within HGI48_RS20265 at 4532.356 kb on - strand at 4532.408 kb on + strand, within HGI48_RS20265 at 4532.408 kb on + strand, within HGI48_RS20265 at 4532.409 kb on - strand, within HGI48_RS20265 at 4532.409 kb on - strand, within HGI48_RS20265 at 4532.409 kb on - strand, within HGI48_RS20265 at 4532.409 kb on - strand, within HGI48_RS20265 at 4532.420 kb on - strand, within HGI48_RS20265 at 4532.556 kb on - strand at 4532.556 kb on - strand at 4532.556 kb on - strand at 4532.556 kb on - strand at 4532.556 kb on - strand at 4532.582 kb on + strand at 4532.582 kb on + strand at 4532.583 kb on - strand at 4532.594 kb on - strand at 4532.644 kb on - strand at 4532.650 kb on + strand at 4532.675 kb on + strand at 4532.675 kb on + strand at 4532.675 kb on + strand at 4532.675 kb on + strand at 4532.676 kb on - strand at 4532.676 kb on - strand at 4532.676 kb on - strand at 4532.695 kb on + strand at 4532.695 kb on + strand at 4532.695 kb on + strand at 4532.696 kb on - strand at 4532.696 kb on - strand at 4532.696 kb on - strand at 4532.696 kb on - strand at 4532.696 kb on - strand at 4532.872 kb on + strand, within HGI48_RS20270 at 4532.872 kb on + strand, within HGI48_RS20270 at 4532.872 kb on + strand, within HGI48_RS20270 at 4532.872 kb on + strand, within HGI48_RS20270 at 4532.872 kb on + strand at 4532.872 kb on + strand at 4532.873 kb on - strand, within HGI48_RS20270 at 4532.873 kb on - strand, within HGI48_RS20270 at 4532.873 kb on - strand, within HGI48_RS20270 at 4532.873 kb on - strand, within HGI48_RS20270 at 4532.873 kb on - strand at 4532.917 kb on + strand, within HGI48_RS20270 at 4532.917 kb on + strand, within HGI48_RS20270 at 4532.917 kb on + strand, within HGI48_RS20270 at 4532.918 kb on - strand, within HGI48_RS20270 at 4532.918 kb on - strand, within HGI48_RS20270 at 4532.939 kb on + strand, within HGI48_RS20270 at 4532.974 kb on + strand, within HGI48_RS20270 at 4532.974 kb on + strand, within HGI48_RS20270 at 4532.975 kb on - strand, within HGI48_RS20270 at 4532.975 kb on - strand at 4532.975 kb on - strand, within HGI48_RS20270 at 4532.975 kb on - strand, within HGI48_RS20270 at 4532.975 kb on - strand, within HGI48_RS20270 at 4532.975 kb on - strand, within HGI48_RS20270 at 4532.975 kb on - strand, within HGI48_RS20270 at 4532.977 kb on + strand, within HGI48_RS20270 at 4533.076 kb on + strand, within HGI48_RS20270 at 4533.076 kb on + strand, within HGI48_RS20270 at 4533.076 kb on + strand, within HGI48_RS20270 at 4533.077 kb on - strand, within HGI48_RS20270 at 4533.162 kb on + strand, within HGI48_RS20270 at 4533.162 kb on + strand, within HGI48_RS20270 at 4533.163 kb on - strand, within HGI48_RS20270 at 4533.163 kb on - strand, within HGI48_RS20270 at 4533.163 kb on - strand, within HGI48_RS20270 at 4533.163 kb on - strand, within HGI48_RS20270 at 4533.163 kb on - strand, within HGI48_RS20270 at 4533.327 kb on - strand, within HGI48_RS20270 at 4533.644 kb on - strand, within HGI48_RS20270 at 4533.644 kb on - strand, within HGI48_RS20270 at 4533.644 kb on - strand, within HGI48_RS20270 at 4533.644 kb on - strand, within HGI48_RS20270 at 4533.644 kb on - strand, within HGI48_RS20270 at 4533.705 kb on - strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.862 kb on + strand, within HGI48_RS20270 at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.863 kb on - strand at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.863 kb on - strand, within HGI48_RS20270 at 4533.875 kb on + strand, within HGI48_RS20270 at 4534.008 kb on + strand at 4534.036 kb on + strand at 4534.037 kb on - strand at 4534.037 kb on - strand at 4534.118 kb on + strand at 4534.118 kb on + strand at 4534.119 kb on - strand at 4534.119 kb on - strand at 4534.126 kb on + strand at 4534.126 kb on + strand at 4534.126 kb on + strand at 4534.127 kb on - strand at 4534.127 kb on - strand at 4534.127 kb on - strand at 4534.156 kb on - strand at 4534.156 kb on - strand at 4534.169 kb on + strand at 4534.169 kb on + strand at 4534.169 kb on + strand at 4534.170 kb on - strand at 4534.170 kb on - strand at 4534.211 kb on - strand at 4534.215 kb on + strand at 4534.215 kb on + strand at 4534.215 kb on + strand at 4534.216 kb on - strand at 4534.216 kb on - strand at 4534.216 kb on - strand at 4534.216 kb on - strand at 4534.227 kb on + strand at 4534.227 kb on + strand at 4534.244 kb on + strand at 4534.244 kb on + strand at 4534.245 kb on - strand at 4534.246 kb on + strand at 4534.247 kb on - strand at 4534.247 kb on - strand at 4534.250 kb on - strand at 4534.308 kb on - strand at 4534.308 kb on - strand at 4534.377 kb on + strand at 4534.377 kb on + strand at 4534.378 kb on - strand at 4534.378 kb on - strand at 4534.464 kb on - strand, within HGI48_RS20275 at 4534.464 kb on - strand, within HGI48_RS20275 at 4534.522 kb on + strand, within HGI48_RS20275 at 4534.522 kb on + strand at 4534.606 kb on + strand, within HGI48_RS20275 at 4534.773 kb on + strand, within HGI48_RS20275 at 4534.773 kb on + strand, within HGI48_RS20275 at 4534.774 kb on - strand, within HGI48_RS20275 at 4534.774 kb on - strand at 4534.790 kb on + strand at 4534.791 kb on - strand, within HGI48_RS20275 at 4534.791 kb on - strand at 4534.941 kb on + strand, within HGI48_RS20275 at 4534.941 kb on + strand, within HGI48_RS20275 at 4534.942 kb on - strand, within HGI48_RS20275 at 4534.942 kb on - strand, within HGI48_RS20275 at 4534.957 kb on + strand, within HGI48_RS20275 at 4534.957 kb on + strand at 4534.957 kb on + strand, within HGI48_RS20275 at 4534.958 kb on - strand, within HGI48_RS20275 at 4534.992 kb on + strand, within HGI48_RS20275 at 4534.992 kb on + strand, within HGI48_RS20275 at 4534.993 kb on - strand, within HGI48_RS20275 at 4534.993 kb on - strand, within HGI48_RS20275 at 4534.993 kb on - strand, within HGI48_RS20275 at 4535.036 kb on + strand at 4535.036 kb on + strand, within HGI48_RS20275 at 4535.037 kb on - strand, within HGI48_RS20275 at 4535.037 kb on - strand, within HGI48_RS20275 at 4535.037 kb on - strand at 4535.064 kb on + strand, within HGI48_RS20275 at 4535.065 kb on - strand, within HGI48_RS20275 at 4535.065 kb on - strand, within HGI48_RS20275 at 4535.094 kb on + strand, within HGI48_RS20275
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 4,531,721 - HGI48_RS20260 0.76 +1.0 4,531,789 - HGI48_RS20260 0.81 +0.1 4,531,789 - HGI48_RS20260 0.81 +0.4 4,531,909 + HGI48_RS20260 0.89 +0.1 4,531,909 + HGI48_RS20260 0.89 +0.4 4,531,909 + HGI48_RS20260 0.89 +0.7 4,531,909 + HGI48_RS20260 0.89 -0.6 4,531,920 + HGI48_RS20260 0.89 -1.0 4,532,055 - -2.0 4,532,096 - +0.4 4,532,096 - -1.5 4,532,104 - -0.7 4,532,109 + -0.2 4,532,109 + -1.8 4,532,109 + -0.2 4,532,109 + +0.1 4,532,110 - -1.4 4,532,110 - -2.5 4,532,110 - -1.8 4,532,110 - +0.2 4,532,110 - +0.4 4,532,110 - +0.8 4,532,110 - -1.8 4,532,110 - -2.8 4,532,119 + +0.2 4,532,120 - -0.5 4,532,120 - +0.6 4,532,120 - -0.6 4,532,135 + -0.4 4,532,136 - -2.0 4,532,136 - -0.0 4,532,136 - -0.2 4,532,136 - +0.3 4,532,138 + +0.8 4,532,138 + -0.9 4,532,138 + -1.0 4,532,139 - +2.0 4,532,139 - -0.0 4,532,139 - -1.7 4,532,139 - +0.8 4,532,139 - +1.2 4,532,141 + -0.9 4,532,142 - +0.8 4,532,164 - +0.4 4,532,205 + +0.6 4,532,205 + +1.3 4,532,206 - +1.2 4,532,242 - +0.8 4,532,285 - HGI48_RS20265 0.30 -1.5 4,532,353 + HGI48_RS20265 0.47 -1.2 4,532,354 - +1.8 4,532,356 - HGI48_RS20265 0.48 +1.1 4,532,356 - +0.8 4,532,408 + HGI48_RS20265 0.60 +0.6 4,532,408 + HGI48_RS20265 0.60 -0.2 4,532,409 - HGI48_RS20265 0.61 +1.2 4,532,409 - HGI48_RS20265 0.61 +1.0 4,532,409 - HGI48_RS20265 0.61 -0.6 4,532,409 - HGI48_RS20265 0.61 -1.4 4,532,420 - HGI48_RS20265 0.63 +0.5 4,532,556 - -0.8 4,532,556 - -0.2 4,532,556 - -1.5 4,532,556 - +0.1 4,532,556 - -0.8 4,532,582 + -0.8 4,532,582 + +0.7 4,532,583 - +0.6 4,532,594 - -0.3 4,532,644 - -1.1 4,532,650 + +0.8 4,532,675 + -1.7 4,532,675 + +1.6 4,532,675 + +1.3 4,532,675 + -0.2 4,532,676 - -1.5 4,532,676 - +0.5 4,532,676 - -0.6 4,532,695 + -0.8 4,532,695 + +1.1 4,532,695 + +0.8 4,532,696 - -1.5 4,532,696 - -2.0 4,532,696 - +0.5 4,532,696 - -0.3 4,532,696 - -2.2 4,532,872 + HGI48_RS20270 0.14 -2.4 4,532,872 + HGI48_RS20270 0.14 -0.8 4,532,872 + HGI48_RS20270 0.14 -1.9 4,532,872 + HGI48_RS20270 0.14 -2.0 4,532,872 + +0.8 4,532,872 + -0.2 4,532,873 - HGI48_RS20270 0.15 +0.7 4,532,873 - HGI48_RS20270 0.15 +0.2 4,532,873 - HGI48_RS20270 0.15 -0.8 4,532,873 - HGI48_RS20270 0.15 -1.1 4,532,873 - +0.2 4,532,917 + HGI48_RS20270 0.18 -1.2 4,532,917 + HGI48_RS20270 0.18 -3.1 4,532,917 + HGI48_RS20270 0.18 -1.3 4,532,918 - HGI48_RS20270 0.18 -0.3 4,532,918 - HGI48_RS20270 0.18 -0.4 4,532,939 + HGI48_RS20270 0.19 -1.7 4,532,974 + HGI48_RS20270 0.21 -1.6 4,532,974 + HGI48_RS20270 0.21 -0.8 4,532,975 - HGI48_RS20270 0.21 -2.5 4,532,975 - +1.4 4,532,975 - HGI48_RS20270 0.21 -0.8 4,532,975 - HGI48_RS20270 0.21 -2.0 4,532,975 - HGI48_RS20270 0.21 +0.3 4,532,975 - HGI48_RS20270 0.21 +0.6 4,532,975 - HGI48_RS20270 0.21 +0.3 4,532,977 + HGI48_RS20270 0.22 -1.5 4,533,076 + HGI48_RS20270 0.28 +1.1 4,533,076 + HGI48_RS20270 0.28 -0.9 4,533,076 + HGI48_RS20270 0.28 +0.1 4,533,077 - HGI48_RS20270 0.28 -0.8 4,533,162 + HGI48_RS20270 0.34 -2.4 4,533,162 + HGI48_RS20270 0.34 -0.4 4,533,163 - HGI48_RS20270 0.34 +0.9 4,533,163 - HGI48_RS20270 0.34 +1.0 4,533,163 - HGI48_RS20270 0.34 +0.1 4,533,163 - HGI48_RS20270 0.34 +1.0 4,533,163 - HGI48_RS20270 0.34 -1.5 4,533,327 - HGI48_RS20270 0.45 -1.0 4,533,644 - HGI48_RS20270 0.67 -2.5 4,533,644 - HGI48_RS20270 0.67 -0.4 4,533,644 - HGI48_RS20270 0.67 +0.5 4,533,644 - HGI48_RS20270 0.67 +0.5 4,533,644 - HGI48_RS20270 0.67 -0.6 4,533,705 - HGI48_RS20270 0.71 -1.5 4,533,862 + HGI48_RS20270 0.81 -1.0 4,533,862 + HGI48_RS20270 0.81 -0.9 4,533,862 + HGI48_RS20270 0.81 -1.0 4,533,862 + HGI48_RS20270 0.81 -2.2 4,533,862 + HGI48_RS20270 0.81 +1.6 4,533,862 + HGI48_RS20270 0.81 -0.2 4,533,862 + HGI48_RS20270 0.81 -1.2 4,533,862 + +0.8 4,533,862 + HGI48_RS20270 0.81 -2.8 4,533,862 + HGI48_RS20270 0.81 -1.9 4,533,863 - HGI48_RS20270 0.81 +0.1 4,533,863 - HGI48_RS20270 0.81 -0.3 4,533,863 - HGI48_RS20270 0.81 -1.8 4,533,863 - +2.1 4,533,863 - HGI48_RS20270 0.81 +0.5 4,533,863 - HGI48_RS20270 0.81 -0.4 4,533,863 - HGI48_RS20270 0.81 -0.0 4,533,863 - HGI48_RS20270 0.81 -0.4 4,533,875 + HGI48_RS20270 0.82 -1.2 4,534,008 + -1.8 4,534,036 + -1.5 4,534,037 - -0.2 4,534,037 - -0.0 4,534,118 + -1.0 4,534,118 + -1.0 4,534,119 - -1.2 4,534,119 - -0.1 4,534,126 + -1.8 4,534,126 + -0.7 4,534,126 + +0.8 4,534,127 - +0.2 4,534,127 - -0.8 4,534,127 - -1.5 4,534,156 - +0.3 4,534,156 - +0.5 4,534,169 + -1.5 4,534,169 + -0.3 4,534,169 + -1.0 4,534,170 - -1.2 4,534,170 - -0.4 4,534,211 - +0.2 4,534,215 + +0.6 4,534,215 + +0.1 4,534,215 + -0.8 4,534,216 - +0.7 4,534,216 - -0.3 4,534,216 - -1.2 4,534,216 - -0.2 4,534,227 + -2.2 4,534,227 + +0.1 4,534,244 + -1.8 4,534,244 + -1.8 4,534,245 - +2.4 4,534,246 + +0.5 4,534,247 - -0.2 4,534,247 - -0.4 4,534,250 - -0.7 4,534,308 - +0.7 4,534,308 - -1.6 4,534,377 + +1.0 4,534,377 + +0.0 4,534,378 - +0.2 4,534,378 - -0.3 4,534,464 - HGI48_RS20275 0.18 +0.3 4,534,464 - HGI48_RS20275 0.18 +0.9 4,534,522 + HGI48_RS20275 0.25 +1.8 4,534,522 + +2.6 4,534,606 + HGI48_RS20275 0.34 -0.4 4,534,773 + HGI48_RS20275 0.53 +0.5 4,534,773 + HGI48_RS20275 0.53 +0.2 4,534,774 - HGI48_RS20275 0.53 +0.7 4,534,774 - +1.8 4,534,790 + -0.2 4,534,791 - HGI48_RS20275 0.55 -0.5 4,534,791 - +0.8 4,534,941 + HGI48_RS20275 0.72 -1.5 4,534,941 + HGI48_RS20275 0.72 +0.3 4,534,942 - HGI48_RS20275 0.72 -1.2 4,534,942 - HGI48_RS20275 0.72 -0.2 4,534,957 + HGI48_RS20275 0.74 +0.4 4,534,957 + +0.2 4,534,957 + HGI48_RS20275 0.74 -2.2 4,534,958 - HGI48_RS20275 0.74 +0.8 4,534,992 + HGI48_RS20275 0.78 -0.2 4,534,992 + HGI48_RS20275 0.78 +0.3 4,534,993 - HGI48_RS20275 0.78 -0.0 4,534,993 - HGI48_RS20275 0.78 +0.6 4,534,993 - HGI48_RS20275 0.78 -1.2 4,535,036 + +0.8 4,535,036 + HGI48_RS20275 0.83 +0.2 4,535,037 - HGI48_RS20275 0.83 -1.8 4,535,037 - HGI48_RS20275 0.83 -0.0 4,535,037 - +0.8 4,535,064 + HGI48_RS20275 0.86 -0.2 4,535,065 - HGI48_RS20275 0.86 -3.2 4,535,065 - HGI48_RS20275 0.86 -0.1 4,535,094 + HGI48_RS20275 0.89 -2.4
Or see this region's nucleotide sequence