Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS19740 and HGI48_RS19745 are separated by 97 nucleotides HGI48_RS19745 and HGI48_RS19750 overlap by 4 nucleotides HGI48_RS19750 and HGI48_RS19755 are separated by 270 nucleotides
HGI48_RS19740: HGI48_RS19740 - phosphoenolpyruvate carboxykinase (ATP), at 4,407,025 to 4,408,644
_RS19740
HGI48_RS19745: HGI48_RS19745 - two-component system sensor histidine kinase EnvZ, at 4,408,742 to 4,410,154
_RS19745
HGI48_RS19750: HGI48_RS19750 - two-component system response regulator OmpR, at 4,410,151 to 4,410,870
_RS19750
HGI48_RS19755: HGI48_RS19755 - transcription elongation factor GreB, at 4,411,141 to 4,411,677
_RS19755
Position (kb)
4408
4409
4410
4411 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 4407.877 kb on + strand, within HGI48_RS19740 at 4407.877 kb on + strand, within HGI48_RS19740 at 4407.878 kb on - strand, within HGI48_RS19740 at 4407.919 kb on - strand, within HGI48_RS19740 at 4407.922 kb on + strand, within HGI48_RS19740 at 4407.922 kb on + strand, within HGI48_RS19740 at 4407.922 kb on + strand, within HGI48_RS19740 at 4407.923 kb on - strand, within HGI48_RS19740 at 4407.923 kb on - strand, within HGI48_RS19740 at 4408.027 kb on + strand, within HGI48_RS19740 at 4408.036 kb on + strand, within HGI48_RS19740 at 4408.036 kb on + strand, within HGI48_RS19740 at 4408.036 kb on + strand at 4408.036 kb on + strand, within HGI48_RS19740 at 4408.036 kb on + strand, within HGI48_RS19740 at 4408.037 kb on - strand, within HGI48_RS19740 at 4408.037 kb on - strand, within HGI48_RS19740 at 4408.037 kb on - strand, within HGI48_RS19740 at 4408.037 kb on - strand at 4408.037 kb on - strand, within HGI48_RS19740 at 4408.037 kb on - strand, within HGI48_RS19740 at 4408.047 kb on + strand, within HGI48_RS19740 at 4408.330 kb on + strand, within HGI48_RS19740 at 4408.331 kb on - strand, within HGI48_RS19740 at 4408.368 kb on + strand, within HGI48_RS19740 at 4408.368 kb on + strand, within HGI48_RS19740 at 4408.369 kb on - strand at 4408.369 kb on - strand, within HGI48_RS19740 at 4408.369 kb on - strand, within HGI48_RS19740 at 4408.369 kb on - strand, within HGI48_RS19740 at 4408.419 kb on + strand, within HGI48_RS19740 at 4408.420 kb on - strand at 4408.450 kb on - strand, within HGI48_RS19740 at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.519 kb on + strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.520 kb on - strand at 4408.591 kb on + strand at 4408.591 kb on + strand at 4408.591 kb on + strand at 4408.591 kb on + strand at 4408.591 kb on + strand at 4408.591 kb on + strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.592 kb on - strand at 4408.593 kb on + strand at 4408.593 kb on + strand at 4408.594 kb on - strand at 4408.656 kb on - strand at 4408.656 kb on - strand at 4408.735 kb on + strand at 4408.736 kb on - strand at 4408.744 kb on - strand at 4408.744 kb on - strand at 4408.847 kb on + strand at 4408.848 kb on - strand at 4408.848 kb on - strand at 4408.851 kb on + strand at 4408.851 kb on + strand at 4408.851 kb on + strand at 4408.852 kb on - strand at 4408.852 kb on - strand at 4408.852 kb on - strand at 4408.918 kb on + strand, within HGI48_RS19745 at 4408.921 kb on + strand, within HGI48_RS19745 at 4408.921 kb on + strand, within HGI48_RS19745 at 4408.922 kb on - strand, within HGI48_RS19745 at 4409.341 kb on + strand, within HGI48_RS19745 at 4409.342 kb on - strand, within HGI48_RS19745 at 4409.347 kb on + strand at 4409.348 kb on - strand, within HGI48_RS19745 at 4409.348 kb on - strand, within HGI48_RS19745 at 4409.362 kb on - strand, within HGI48_RS19745 at 4409.362 kb on - strand, within HGI48_RS19745 at 4409.452 kb on + strand, within HGI48_RS19745 at 4409.554 kb on + strand at 4409.555 kb on - strand, within HGI48_RS19745 at 4409.557 kb on + strand, within HGI48_RS19745 at 4409.557 kb on + strand, within HGI48_RS19745 at 4409.558 kb on - strand, within HGI48_RS19745 at 4409.558 kb on - strand, within HGI48_RS19745 at 4409.558 kb on - strand, within HGI48_RS19745 at 4409.558 kb on - strand, within HGI48_RS19745 at 4409.575 kb on + strand, within HGI48_RS19745 at 4409.649 kb on - strand, within HGI48_RS19745 at 4409.653 kb on + strand, within HGI48_RS19745 at 4409.665 kb on + strand, within HGI48_RS19745 at 4409.666 kb on - strand, within HGI48_RS19745 at 4409.841 kb on + strand, within HGI48_RS19745 at 4409.841 kb on + strand, within HGI48_RS19745 at 4409.842 kb on - strand, within HGI48_RS19745 at 4409.842 kb on - strand, within HGI48_RS19745 at 4409.842 kb on - strand, within HGI48_RS19745 at 4409.890 kb on - strand at 4409.890 kb on - strand, within HGI48_RS19745 at 4409.890 kb on - strand, within HGI48_RS19745 at 4410.063 kb on + strand at 4410.063 kb on + strand at 4410.064 kb on - strand at 4410.064 kb on - strand at 4410.182 kb on + strand at 4410.209 kb on + strand at 4410.210 kb on - strand at 4410.210 kb on - strand at 4410.210 kb on - strand at 4410.291 kb on - strand, within HGI48_RS19750 at 4410.525 kb on + strand, within HGI48_RS19750 at 4410.567 kb on - strand, within HGI48_RS19750 at 4410.630 kb on + strand, within HGI48_RS19750 at 4410.631 kb on - strand, within HGI48_RS19750 at 4410.631 kb on - strand, within HGI48_RS19750 at 4410.631 kb on - strand, within HGI48_RS19750 at 4410.774 kb on + strand, within HGI48_RS19750 at 4410.803 kb on + strand at 4410.857 kb on + strand at 4410.892 kb on + strand at 4410.912 kb on + strand at 4410.913 kb on - strand at 4410.932 kb on + strand at 4410.973 kb on + strand at 4410.975 kb on + strand at 4410.975 kb on + strand at 4410.975 kb on + strand at 4410.976 kb on - strand at 4410.976 kb on - strand at 4410.976 kb on - strand at 4410.976 kb on - strand at 4410.976 kb on - strand at 4410.976 kb on - strand at 4410.977 kb on + strand at 4410.977 kb on + strand at 4410.977 kb on + strand at 4410.977 kb on + strand at 4410.977 kb on + strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4410.978 kb on - strand at 4411.013 kb on - strand at 4411.019 kb on + strand at 4411.020 kb on - strand at 4411.080 kb on - strand at 4411.080 kb on - strand at 4411.084 kb on + strand at 4411.084 kb on + strand at 4411.085 kb on - strand at 4411.085 kb on - strand at 4411.085 kb on - strand at 4411.103 kb on + strand at 4411.103 kb on + strand at 4411.103 kb on + strand at 4411.103 kb on + strand at 4411.104 kb on - strand at 4411.104 kb on - strand at 4411.104 kb on - strand at 4411.104 kb on - strand at 4411.104 kb on - strand at 4411.104 kb on - strand at 4411.105 kb on + strand at 4411.115 kb on - strand at 4411.123 kb on + strand at 4411.123 kb on + strand at 4411.124 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 4,407,877 + HGI48_RS19740 0.53 +1.0 4,407,877 + HGI48_RS19740 0.53 +1.4 4,407,878 - HGI48_RS19740 0.53 +1.4 4,407,919 - HGI48_RS19740 0.55 -0.5 4,407,922 + HGI48_RS19740 0.55 +0.8 4,407,922 + HGI48_RS19740 0.55 -1.0 4,407,922 + HGI48_RS19740 0.55 +1.6 4,407,923 - HGI48_RS19740 0.55 -0.0 4,407,923 - HGI48_RS19740 0.55 +0.8 4,408,027 + HGI48_RS19740 0.62 -0.3 4,408,036 + HGI48_RS19740 0.62 -0.1 4,408,036 + HGI48_RS19740 0.62 -0.0 4,408,036 + +1.2 4,408,036 + HGI48_RS19740 0.62 +0.2 4,408,036 + HGI48_RS19740 0.62 +0.0 4,408,037 - HGI48_RS19740 0.62 +0.3 4,408,037 - HGI48_RS19740 0.62 +1.0 4,408,037 - HGI48_RS19740 0.62 +0.3 4,408,037 - -0.8 4,408,037 - HGI48_RS19740 0.62 +0.4 4,408,037 - HGI48_RS19740 0.62 -0.1 4,408,047 + HGI48_RS19740 0.63 +2.1 4,408,330 + HGI48_RS19740 0.81 +0.8 4,408,331 - HGI48_RS19740 0.81 -0.4 4,408,368 + HGI48_RS19740 0.83 -3.8 4,408,368 + HGI48_RS19740 0.83 -0.2 4,408,369 - +0.8 4,408,369 - HGI48_RS19740 0.83 +0.8 4,408,369 - HGI48_RS19740 0.83 -0.2 4,408,369 - HGI48_RS19740 0.83 -1.7 4,408,419 + HGI48_RS19740 0.86 +0.4 4,408,420 - -0.2 4,408,450 - HGI48_RS19740 0.88 +0.6 4,408,519 + +0.0 4,408,519 + -0.1 4,408,519 + -1.2 4,408,519 + +0.5 4,408,519 + +2.4 4,408,519 + +0.1 4,408,519 + +0.1 4,408,519 + +1.8 4,408,519 + -1.2 4,408,519 + -1.8 4,408,519 + -1.6 4,408,519 + -0.6 4,408,520 - +1.8 4,408,520 - -0.4 4,408,520 - +0.8 4,408,520 - +0.1 4,408,520 - +0.5 4,408,520 - +1.9 4,408,520 - -1.6 4,408,520 - -0.2 4,408,520 - +0.2 4,408,591 + -0.6 4,408,591 + -0.2 4,408,591 + +1.0 4,408,591 + +0.2 4,408,591 + +0.8 4,408,591 + +0.2 4,408,592 - +2.1 4,408,592 - +0.4 4,408,592 - -0.6 4,408,592 - -1.8 4,408,592 - -1.3 4,408,592 - -0.6 4,408,592 - -1.6 4,408,592 - -0.2 4,408,593 + +2.1 4,408,593 + +0.1 4,408,594 - +1.2 4,408,656 - +0.8 4,408,656 - +0.1 4,408,735 + -2.4 4,408,736 - -0.0 4,408,744 - -1.4 4,408,744 - +0.0 4,408,847 + -0.1 4,408,848 - -0.2 4,408,848 - -0.2 4,408,851 + -1.4 4,408,851 + -2.3 4,408,851 + -1.6 4,408,852 - +0.8 4,408,852 - -1.8 4,408,852 - +0.1 4,408,918 + HGI48_RS19745 0.12 -0.2 4,408,921 + HGI48_RS19745 0.13 -1.8 4,408,921 + HGI48_RS19745 0.13 -3.5 4,408,922 - HGI48_RS19745 0.13 -0.8 4,409,341 + HGI48_RS19745 0.42 -0.6 4,409,342 - HGI48_RS19745 0.42 -0.4 4,409,347 + -0.8 4,409,348 - HGI48_RS19745 0.43 +1.3 4,409,348 - HGI48_RS19745 0.43 -0.5 4,409,362 - HGI48_RS19745 0.44 -1.3 4,409,362 - HGI48_RS19745 0.44 -1.2 4,409,452 + HGI48_RS19745 0.50 -1.6 4,409,554 + -0.8 4,409,555 - HGI48_RS19745 0.58 -2.3 4,409,557 + HGI48_RS19745 0.58 -0.8 4,409,557 + HGI48_RS19745 0.58 -0.2 4,409,558 - HGI48_RS19745 0.58 +0.5 4,409,558 - HGI48_RS19745 0.58 +1.5 4,409,558 - HGI48_RS19745 0.58 -0.1 4,409,558 - HGI48_RS19745 0.58 -2.1 4,409,575 + HGI48_RS19745 0.59 -2.4 4,409,649 - HGI48_RS19745 0.64 -1.8 4,409,653 + HGI48_RS19745 0.64 -1.2 4,409,665 + HGI48_RS19745 0.65 -3.2 4,409,666 - HGI48_RS19745 0.65 -2.4 4,409,841 + HGI48_RS19745 0.78 -0.1 4,409,841 + HGI48_RS19745 0.78 -0.6 4,409,842 - HGI48_RS19745 0.78 -1.8 4,409,842 - HGI48_RS19745 0.78 -1.2 4,409,842 - HGI48_RS19745 0.78 -1.6 4,409,890 - -0.2 4,409,890 - HGI48_RS19745 0.81 -1.2 4,409,890 - HGI48_RS19745 0.81 -0.2 4,410,063 + -2.2 4,410,063 + -2.8 4,410,064 - -1.8 4,410,064 - -1.6 4,410,182 + -0.8 4,410,209 + +1.5 4,410,210 - -0.6 4,410,210 - -1.3 4,410,210 - +1.2 4,410,291 - HGI48_RS19750 0.19 -1.8 4,410,525 + HGI48_RS19750 0.52 -3.2 4,410,567 - HGI48_RS19750 0.58 -0.4 4,410,630 + HGI48_RS19750 0.67 -1.9 4,410,631 - HGI48_RS19750 0.67 -1.0 4,410,631 - HGI48_RS19750 0.67 +0.6 4,410,631 - HGI48_RS19750 0.67 -0.2 4,410,774 + HGI48_RS19750 0.87 +0.4 4,410,803 + -0.5 4,410,857 + -2.9 4,410,892 + -0.2 4,410,912 + -0.6 4,410,913 - +0.0 4,410,932 + -1.2 4,410,973 + -1.2 4,410,975 + -2.0 4,410,975 + +0.3 4,410,975 + -0.9 4,410,976 - -0.6 4,410,976 - -0.2 4,410,976 - +1.0 4,410,976 - +0.4 4,410,976 - +0.2 4,410,976 - -0.3 4,410,977 + +0.0 4,410,977 + -0.2 4,410,977 + -0.8 4,410,977 + +0.8 4,410,977 + +0.1 4,410,978 - -0.7 4,410,978 - -1.8 4,410,978 - +0.6 4,410,978 - +1.0 4,410,978 - +1.2 4,410,978 - +1.2 4,410,978 - -0.4 4,410,978 - -0.1 4,411,013 - -1.0 4,411,019 + +2.9 4,411,020 - -1.5 4,411,080 - +0.5 4,411,080 - -0.5 4,411,084 + -1.8 4,411,084 + -0.4 4,411,085 - +0.7 4,411,085 - -0.0 4,411,085 - +0.5 4,411,103 + -1.4 4,411,103 + -0.5 4,411,103 + -0.3 4,411,103 + +0.1 4,411,104 - -0.6 4,411,104 - -1.2 4,411,104 - +0.8 4,411,104 - -0.2 4,411,104 - +0.2 4,411,104 - +0.6 4,411,105 + -0.8 4,411,115 - -1.5 4,411,123 + -1.5 4,411,123 + +0.8 4,411,124 - -2.0
Or see this region's nucleotide sequence