Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS18365 and HGI48_RS18370 overlap by 4 nucleotides HGI48_RS18370 and HGI48_RS18375 are separated by 51 nucleotides HGI48_RS18375 and HGI48_RS18380 are separated by 14 nucleotides HGI48_RS18380 and HGI48_RS18385 are separated by 225 nucleotides
HGI48_RS18365: HGI48_RS18365 - MDR efflux pump AcrAB transcriptional activator RobA, at 4,122,830 to 4,123,687
_RS18365
HGI48_RS18370: HGI48_RS18370 - 2,3-diphosphoglycerate-dependent phosphoglycerate mutase GpmB, at 4,123,684 to 4,124,334
_RS18370
HGI48_RS18375: HGI48_RS18375 - inosine/xanthosine triphosphatase, at 4,124,386 to 4,124,925
_RS18375
HGI48_RS18380: HGI48_RS18380 - trp operon repressor, at 4,124,940 to 4,125,272
_RS18380
HGI48_RS18385: HGI48_RS18385 - murein transglycosylase, at 4,125,498 to 4,127,429
_RS18385
Position (kb) 4124
4125 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.421 kb on + strand, within HGI48_RS18365 at 4123.422 kb on - strand, within HGI48_RS18365 at 4123.422 kb on - strand, within HGI48_RS18365 at 4123.422 kb on - strand at 4123.422 kb on - strand, within HGI48_RS18365 at 4123.423 kb on + strand, within HGI48_RS18365 at 4123.423 kb on + strand, within HGI48_RS18365 at 4123.423 kb on + strand, within HGI48_RS18365 at 4123.424 kb on - strand, within HGI48_RS18365 at 4123.500 kb on - strand, within HGI48_RS18365 at 4123.510 kb on + strand, within HGI48_RS18365 at 4123.510 kb on + strand, within HGI48_RS18365 at 4123.510 kb on + strand, within HGI48_RS18365 at 4123.510 kb on + strand, within HGI48_RS18365 at 4123.511 kb on - strand, within HGI48_RS18365 at 4123.514 kb on + strand, within HGI48_RS18365 at 4123.514 kb on + strand, within HGI48_RS18365 at 4123.514 kb on + strand, within HGI48_RS18365 at 4123.514 kb on + strand at 4123.514 kb on + strand, within HGI48_RS18365 at 4123.515 kb on - strand, within HGI48_RS18365 at 4123.515 kb on - strand, within HGI48_RS18365 at 4123.515 kb on - strand, within HGI48_RS18365 at 4123.515 kb on - strand, within HGI48_RS18365 at 4123.550 kb on - strand, within HGI48_RS18365 at 4123.560 kb on - strand, within HGI48_RS18365 at 4123.564 kb on + strand, within HGI48_RS18365 at 4123.564 kb on + strand at 4123.580 kb on + strand, within HGI48_RS18365 at 4123.580 kb on + strand, within HGI48_RS18365 at 4123.580 kb on + strand, within HGI48_RS18365 at 4123.580 kb on + strand, within HGI48_RS18365 at 4123.581 kb on - strand, within HGI48_RS18365 at 4123.581 kb on - strand, within HGI48_RS18365 at 4123.581 kb on - strand at 4123.581 kb on - strand, within HGI48_RS18365 at 4123.582 kb on + strand, within HGI48_RS18365 at 4123.582 kb on + strand, within HGI48_RS18365 at 4123.582 kb on + strand, within HGI48_RS18365 at 4123.582 kb on + strand, within HGI48_RS18365 at 4123.583 kb on - strand, within HGI48_RS18365 at 4123.664 kb on + strand at 4123.665 kb on - strand at 4123.665 kb on - strand at 4123.782 kb on - strand, within HGI48_RS18370 at 4123.782 kb on - strand, within HGI48_RS18370 at 4123.854 kb on + strand, within HGI48_RS18370 at 4123.854 kb on + strand, within HGI48_RS18370 at 4123.854 kb on + strand, within HGI48_RS18370 at 4123.854 kb on + strand, within HGI48_RS18370 at 4123.855 kb on - strand, within HGI48_RS18370 at 4123.947 kb on + strand, within HGI48_RS18370 at 4123.947 kb on + strand, within HGI48_RS18370 at 4123.948 kb on - strand, within HGI48_RS18370 at 4123.948 kb on - strand, within HGI48_RS18370 at 4123.987 kb on - strand, within HGI48_RS18370 at 4124.079 kb on + strand, within HGI48_RS18370 at 4124.203 kb on - strand, within HGI48_RS18370 at 4124.321 kb on + strand at 4124.321 kb on + strand at 4124.321 kb on + strand at 4124.321 kb on + strand at 4124.321 kb on + strand at 4124.322 kb on - strand at 4124.322 kb on - strand at 4124.322 kb on - strand at 4124.323 kb on + strand at 4124.323 kb on + strand at 4124.323 kb on + strand at 4124.323 kb on + strand at 4124.324 kb on - strand at 4124.324 kb on - strand at 4124.324 kb on - strand at 4124.324 kb on - strand at 4124.324 kb on - strand at 4124.324 kb on - strand at 4124.329 kb on + strand at 4124.330 kb on - strand at 4124.330 kb on - strand at 4124.350 kb on + strand at 4124.350 kb on + strand at 4124.350 kb on + strand at 4124.351 kb on - strand at 4124.363 kb on + strand at 4124.363 kb on + strand at 4124.367 kb on + strand at 4124.367 kb on + strand at 4124.368 kb on - strand at 4124.375 kb on - strand at 4124.384 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.385 kb on + strand at 4124.386 kb on - strand at 4124.386 kb on - strand at 4124.386 kb on - strand at 4124.386 kb on - strand at 4124.386 kb on - strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.389 kb on + strand at 4124.390 kb on - strand at 4124.390 kb on - strand at 4124.390 kb on - strand at 4124.390 kb on - strand at 4124.390 kb on - strand at 4124.390 kb on - strand at 4124.406 kb on + strand at 4124.442 kb on - strand, within HGI48_RS18375 at 4124.469 kb on + strand, within HGI48_RS18375 at 4124.495 kb on + strand, within HGI48_RS18375 at 4124.496 kb on - strand, within HGI48_RS18375 at 4124.496 kb on - strand, within HGI48_RS18375 at 4124.522 kb on + strand, within HGI48_RS18375 at 4124.522 kb on + strand, within HGI48_RS18375 at 4124.523 kb on - strand at 4124.523 kb on - strand, within HGI48_RS18375 at 4124.699 kb on + strand, within HGI48_RS18375 at 4124.699 kb on + strand, within HGI48_RS18375 at 4124.699 kb on + strand, within HGI48_RS18375 at 4124.700 kb on - strand, within HGI48_RS18375 at 4124.700 kb on - strand, within HGI48_RS18375 at 4124.845 kb on + strand, within HGI48_RS18375 at 4124.845 kb on + strand, within HGI48_RS18375 at 4124.845 kb on + strand, within HGI48_RS18375 at 4124.845 kb on + strand at 4124.846 kb on - strand, within HGI48_RS18375 at 4124.846 kb on - strand, within HGI48_RS18375 at 4124.846 kb on - strand at 4124.846 kb on - strand, within HGI48_RS18375 at 4124.846 kb on - strand, within HGI48_RS18375 at 4124.848 kb on + strand, within HGI48_RS18375 at 4124.848 kb on + strand, within HGI48_RS18375 at 4124.849 kb on - strand, within HGI48_RS18375 at 4124.884 kb on - strand at 4124.911 kb on - strand at 4124.949 kb on - strand at 4125.104 kb on + strand, within HGI48_RS18380 at 4125.105 kb on - strand, within HGI48_RS18380 at 4125.295 kb on + strand at 4125.295 kb on + strand at 4125.307 kb on + strand at 4125.312 kb on + strand at 4125.312 kb on + strand at 4125.313 kb on - strand at 4125.315 kb on + strand at 4125.316 kb on - strand at 4125.321 kb on + strand at 4125.350 kb on - strand at 4125.350 kb on - strand at 4125.439 kb on - strand at 4125.453 kb on + strand at 4125.453 kb on + strand at 4125.453 kb on + strand at 4125.453 kb on + strand at 4125.454 kb on - strand at 4125.454 kb on - strand at 4125.454 kb on - strand at 4125.457 kb on + strand at 4125.457 kb on + strand at 4125.457 kb on + strand at 4125.457 kb on + strand at 4125.457 kb on + strand at 4125.457 kb on + strand at 4125.457 kb on + strand at 4125.458 kb on - strand at 4125.458 kb on - strand at 4125.458 kb on - strand at 4125.458 kb on - strand at 4125.458 kb on - strand at 4125.458 kb on - strand at 4125.577 kb on + strand at 4125.578 kb on - strand at 4125.585 kb on + strand at 4125.585 kb on + strand at 4125.598 kb on + strand at 4125.599 kb on - strand at 4125.599 kb on - strand at 4125.677 kb on + strand at 4125.703 kb on + strand, within HGI48_RS18385 at 4125.745 kb on + strand, within HGI48_RS18385 at 4125.751 kb on + strand, within HGI48_RS18385 at 4125.751 kb on + strand, within HGI48_RS18385 at 4125.751 kb on + strand, within HGI48_RS18385 at 4125.751 kb on + strand, within HGI48_RS18385 at 4125.752 kb on - strand, within HGI48_RS18385 at 4125.752 kb on - strand, within HGI48_RS18385 at 4125.760 kb on + strand, within HGI48_RS18385 at 4125.760 kb on + strand at 4125.761 kb on - strand, within HGI48_RS18385 at 4125.780 kb on - strand, within HGI48_RS18385 at 4125.780 kb on - strand, within HGI48_RS18385 at 4125.815 kb on + strand, within HGI48_RS18385 at 4125.815 kb on + strand, within HGI48_RS18385 at 4125.816 kb on - strand, within HGI48_RS18385 at 4125.816 kb on - strand, within HGI48_RS18385 at 4125.816 kb on - strand, within HGI48_RS18385 at 4125.816 kb on - strand, within HGI48_RS18385 at 4125.817 kb on + strand, within HGI48_RS18385 at 4125.817 kb on + strand, within HGI48_RS18385 at 4125.818 kb on - strand, within HGI48_RS18385 at 4125.818 kb on - strand, within HGI48_RS18385 at 4125.818 kb on - strand, within HGI48_RS18385 at 4125.830 kb on + strand, within HGI48_RS18385 at 4125.830 kb on + strand, within HGI48_RS18385 at 4125.830 kb on + strand at 4125.830 kb on + strand at 4125.830 kb on + strand, within HGI48_RS18385 at 4125.830 kb on + strand at 4125.830 kb on + strand, within HGI48_RS18385 at 4125.831 kb on - strand, within HGI48_RS18385 at 4125.831 kb on - strand, within HGI48_RS18385 at 4125.831 kb on - strand, within HGI48_RS18385
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 4,123,421 + HGI48_RS18365 0.69 +0.0 4,123,421 + HGI48_RS18365 0.69 +0.3 4,123,421 + HGI48_RS18365 0.69 -2.9 4,123,421 + HGI48_RS18365 0.69 -0.5 4,123,421 + HGI48_RS18365 0.69 -1.3 4,123,421 + HGI48_RS18365 0.69 +1.3 4,123,421 + HGI48_RS18365 0.69 +1.4 4,123,422 - HGI48_RS18365 0.69 -0.4 4,123,422 - HGI48_RS18365 0.69 +1.8 4,123,422 - -0.9 4,123,422 - HGI48_RS18365 0.69 +0.6 4,123,423 + HGI48_RS18365 0.69 -0.3 4,123,423 + HGI48_RS18365 0.69 -0.3 4,123,423 + HGI48_RS18365 0.69 -1.6 4,123,424 - HGI48_RS18365 0.69 +0.7 4,123,500 - HGI48_RS18365 0.78 -0.1 4,123,510 + HGI48_RS18365 0.79 +0.9 4,123,510 + HGI48_RS18365 0.79 +0.1 4,123,510 + HGI48_RS18365 0.79 -0.5 4,123,510 + HGI48_RS18365 0.79 +0.4 4,123,511 - HGI48_RS18365 0.79 +0.4 4,123,514 + HGI48_RS18365 0.80 -1.5 4,123,514 + HGI48_RS18365 0.80 -0.2 4,123,514 + HGI48_RS18365 0.80 -0.3 4,123,514 + +1.1 4,123,514 + HGI48_RS18365 0.80 +1.3 4,123,515 - HGI48_RS18365 0.80 -0.5 4,123,515 - HGI48_RS18365 0.80 +0.1 4,123,515 - HGI48_RS18365 0.80 -0.8 4,123,515 - HGI48_RS18365 0.80 -0.5 4,123,550 - HGI48_RS18365 0.84 -0.3 4,123,560 - HGI48_RS18365 0.85 +0.8 4,123,564 + HGI48_RS18365 0.86 +1.2 4,123,564 + +1.4 4,123,580 + HGI48_RS18365 0.87 +1.7 4,123,580 + HGI48_RS18365 0.87 -0.5 4,123,580 + HGI48_RS18365 0.87 -0.3 4,123,580 + HGI48_RS18365 0.87 -0.4 4,123,581 - HGI48_RS18365 0.88 +1.0 4,123,581 - HGI48_RS18365 0.88 -0.7 4,123,581 - +2.4 4,123,581 - HGI48_RS18365 0.88 -1.1 4,123,582 + HGI48_RS18365 0.88 -0.4 4,123,582 + HGI48_RS18365 0.88 -1.7 4,123,582 + HGI48_RS18365 0.88 -0.6 4,123,582 + HGI48_RS18365 0.88 +0.6 4,123,583 - HGI48_RS18365 0.88 +0.5 4,123,664 + +1.3 4,123,665 - -0.8 4,123,665 - -0.1 4,123,782 - HGI48_RS18370 0.15 +0.1 4,123,782 - HGI48_RS18370 0.15 -0.3 4,123,854 + HGI48_RS18370 0.26 +0.2 4,123,854 + HGI48_RS18370 0.26 +0.5 4,123,854 + HGI48_RS18370 0.26 +0.6 4,123,854 + HGI48_RS18370 0.26 +0.3 4,123,855 - HGI48_RS18370 0.26 -0.0 4,123,947 + HGI48_RS18370 0.40 +0.2 4,123,947 + HGI48_RS18370 0.40 +1.5 4,123,948 - HGI48_RS18370 0.41 -1.6 4,123,948 - HGI48_RS18370 0.41 -0.3 4,123,987 - HGI48_RS18370 0.47 +1.1 4,124,079 + HGI48_RS18370 0.61 +1.4 4,124,203 - HGI48_RS18370 0.80 +0.8 4,124,321 + +0.7 4,124,321 + +0.2 4,124,321 + -1.8 4,124,321 + -2.3 4,124,321 + -0.1 4,124,322 - +0.0 4,124,322 - +0.7 4,124,322 - -2.1 4,124,323 + +2.7 4,124,323 + +1.5 4,124,323 + +0.5 4,124,323 + +0.7 4,124,324 - +0.7 4,124,324 - -1.2 4,124,324 - +1.3 4,124,324 - -0.3 4,124,324 - -0.5 4,124,324 - -0.3 4,124,329 + -0.9 4,124,330 - -0.6 4,124,330 - -0.3 4,124,350 + +0.4 4,124,350 + -0.5 4,124,350 + +1.6 4,124,351 - -3.3 4,124,363 + +0.7 4,124,363 + -0.5 4,124,367 + -0.0 4,124,367 + +1.1 4,124,368 - -0.6 4,124,375 - -0.7 4,124,384 + -2.3 4,124,385 + -2.4 4,124,385 + -1.9 4,124,385 + -1.6 4,124,385 + -1.9 4,124,385 + -1.9 4,124,385 + -3.2 4,124,385 + -1.5 4,124,385 + -3.6 4,124,385 + -2.3 4,124,385 + -2.1 4,124,386 - -0.5 4,124,386 - -1.6 4,124,386 - -1.1 4,124,386 - -0.9 4,124,386 - -2.2 4,124,389 + +0.4 4,124,389 + -0.9 4,124,389 + -2.1 4,124,389 + -0.3 4,124,389 + -2.9 4,124,389 + +1.1 4,124,389 + -1.3 4,124,389 + -3.0 4,124,389 + -1.6 4,124,390 - -2.1 4,124,390 - +0.7 4,124,390 - +0.7 4,124,390 - -2.3 4,124,390 - -1.6 4,124,390 - -0.6 4,124,406 + -2.9 4,124,442 - HGI48_RS18375 0.10 +0.7 4,124,469 + HGI48_RS18375 0.15 -1.6 4,124,495 + HGI48_RS18375 0.20 -1.6 4,124,496 - HGI48_RS18375 0.20 -2.1 4,124,496 - HGI48_RS18375 0.20 -1.5 4,124,522 + HGI48_RS18375 0.25 -1.1 4,124,522 + HGI48_RS18375 0.25 -2.5 4,124,523 - -0.9 4,124,523 - HGI48_RS18375 0.25 -0.5 4,124,699 + HGI48_RS18375 0.58 -2.1 4,124,699 + HGI48_RS18375 0.58 -0.3 4,124,699 + HGI48_RS18375 0.58 -0.2 4,124,700 - HGI48_RS18375 0.58 -1.6 4,124,700 - HGI48_RS18375 0.58 -3.1 4,124,845 + HGI48_RS18375 0.85 -2.9 4,124,845 + HGI48_RS18375 0.85 -3.4 4,124,845 + HGI48_RS18375 0.85 -1.6 4,124,845 + +0.1 4,124,846 - HGI48_RS18375 0.85 +0.3 4,124,846 - HGI48_RS18375 0.85 -1.9 4,124,846 - +2.1 4,124,846 - HGI48_RS18375 0.85 -1.9 4,124,846 - HGI48_RS18375 0.85 -2.1 4,124,848 + HGI48_RS18375 0.86 -0.6 4,124,848 + HGI48_RS18375 0.86 -2.9 4,124,849 - HGI48_RS18375 0.86 -2.4 4,124,884 - -3.0 4,124,911 - +0.0 4,124,949 - -1.6 4,125,104 + HGI48_RS18380 0.49 -0.3 4,125,105 - HGI48_RS18380 0.50 +0.6 4,125,295 + -1.6 4,125,295 + +2.3 4,125,307 + -1.1 4,125,312 + +0.7 4,125,312 + -1.3 4,125,313 - +0.5 4,125,315 + +0.7 4,125,316 - -0.2 4,125,321 + -0.2 4,125,350 - -1.3 4,125,350 - -0.9 4,125,439 - -0.9 4,125,453 + +1.5 4,125,453 + +0.1 4,125,453 + -1.3 4,125,453 + -0.1 4,125,454 - -1.3 4,125,454 - -2.3 4,125,454 - -1.9 4,125,457 + -0.9 4,125,457 + -0.1 4,125,457 + -0.1 4,125,457 + -0.3 4,125,457 + +1.1 4,125,457 + +0.0 4,125,457 + +1.1 4,125,458 - -0.6 4,125,458 - +1.1 4,125,458 - +0.3 4,125,458 - +0.3 4,125,458 - -0.3 4,125,458 - -0.5 4,125,577 + -0.7 4,125,578 - +0.2 4,125,585 + +0.5 4,125,585 + +0.5 4,125,598 + +0.4 4,125,599 - +1.3 4,125,599 - +0.2 4,125,677 + -1.0 4,125,703 + HGI48_RS18385 0.11 +0.7 4,125,745 + HGI48_RS18385 0.13 +1.1 4,125,751 + HGI48_RS18385 0.13 -1.6 4,125,751 + HGI48_RS18385 0.13 +0.1 4,125,751 + HGI48_RS18385 0.13 +0.5 4,125,751 + HGI48_RS18385 0.13 +0.4 4,125,752 - HGI48_RS18385 0.13 +0.1 4,125,752 - HGI48_RS18385 0.13 -0.3 4,125,760 + HGI48_RS18385 0.14 +1.3 4,125,760 + -0.9 4,125,761 - HGI48_RS18385 0.14 -0.3 4,125,780 - HGI48_RS18385 0.15 +0.4 4,125,780 - HGI48_RS18385 0.15 -0.3 4,125,815 + HGI48_RS18385 0.16 -1.4 4,125,815 + HGI48_RS18385 0.16 -0.5 4,125,816 - HGI48_RS18385 0.16 +0.9 4,125,816 - HGI48_RS18385 0.16 -0.3 4,125,816 - HGI48_RS18385 0.16 -1.7 4,125,816 - HGI48_RS18385 0.16 +0.3 4,125,817 + HGI48_RS18385 0.17 +0.3 4,125,817 + HGI48_RS18385 0.17 +0.2 4,125,818 - HGI48_RS18385 0.17 +0.1 4,125,818 - HGI48_RS18385 0.17 +0.5 4,125,818 - HGI48_RS18385 0.17 +1.2 4,125,830 + HGI48_RS18385 0.17 +0.7 4,125,830 + HGI48_RS18385 0.17 +0.1 4,125,830 + +1.1 4,125,830 + -0.9 4,125,830 + HGI48_RS18385 0.17 +0.5 4,125,830 + +0.1 4,125,830 + HGI48_RS18385 0.17 +1.9 4,125,831 - HGI48_RS18385 0.17 +0.6 4,125,831 - HGI48_RS18385 0.17 -2.5 4,125,831 - HGI48_RS18385 0.17 +2.0
Or see this region's nucleotide sequence