Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS13990 and HGI48_RS13995 are separated by 120 nucleotides HGI48_RS13995 and HGI48_RS14000 are separated by 244 nucleotides HGI48_RS14000 and HGI48_RS14005 are separated by 56 nucleotides HGI48_RS14005 and HGI48_RS14010 are separated by 74 nucleotides
HGI48_RS13990: HGI48_RS13990 - DNA mismatch endonuclease Vsr, at 3,130,594 to 3,131,031
_RS13990
HGI48_RS13995: HGI48_RS13995 - integrase, at 3,131,152 to 3,131,346
_RS13995
HGI48_RS14000: HGI48_RS14000 - NADP-dependent oxidoreductase, at 3,131,591 to 3,132,610
_RS14000
HGI48_RS14005: HGI48_RS14005 - SDR family oxidoreductase, at 3,132,667 to 3,133,449
_RS14005
HGI48_RS14010: HGI48_RS14010 - alkene reductase, at 3,133,524 to 3,134,615
_RS14010
Position (kb)
3131
3132
3133 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 3130.605 kb on + strand at 3130.605 kb on + strand at 3130.624 kb on + strand at 3130.624 kb on + strand at 3130.625 kb on - strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.626 kb on + strand at 3130.627 kb on - strand at 3130.627 kb on - strand at 3130.627 kb on - strand at 3130.627 kb on - strand at 3130.627 kb on - strand at 3130.627 kb on - strand at 3130.628 kb on + strand at 3130.628 kb on + strand at 3130.628 kb on + strand at 3130.628 kb on + strand at 3130.628 kb on + strand at 3130.628 kb on + strand at 3130.628 kb on + strand at 3130.629 kb on - strand at 3130.629 kb on - strand at 3130.629 kb on - strand at 3130.668 kb on + strand, within HGI48_RS13990 at 3130.668 kb on + strand at 3130.668 kb on + strand, within HGI48_RS13990 at 3130.668 kb on + strand, within HGI48_RS13990 at 3130.669 kb on - strand, within HGI48_RS13990 at 3130.669 kb on - strand, within HGI48_RS13990 at 3130.669 kb on - strand, within HGI48_RS13990 at 3130.670 kb on + strand, within HGI48_RS13990 at 3130.671 kb on - strand, within HGI48_RS13990 at 3130.671 kb on - strand, within HGI48_RS13990 at 3130.683 kb on + strand, within HGI48_RS13990 at 3130.683 kb on + strand, within HGI48_RS13990 at 3130.683 kb on + strand, within HGI48_RS13990 at 3130.684 kb on - strand, within HGI48_RS13990 at 3130.688 kb on - strand, within HGI48_RS13990 at 3130.688 kb on - strand, within HGI48_RS13990 at 3130.712 kb on + strand, within HGI48_RS13990 at 3130.712 kb on + strand, within HGI48_RS13990 at 3130.713 kb on - strand, within HGI48_RS13990 at 3130.822 kb on - strand, within HGI48_RS13990 at 3130.857 kb on + strand, within HGI48_RS13990 at 3130.857 kb on + strand, within HGI48_RS13990 at 3130.857 kb on + strand, within HGI48_RS13990 at 3130.857 kb on + strand, within HGI48_RS13990 at 3130.858 kb on - strand, within HGI48_RS13990 at 3130.858 kb on - strand, within HGI48_RS13990 at 3130.858 kb on - strand, within HGI48_RS13990 at 3130.858 kb on - strand, within HGI48_RS13990 at 3130.858 kb on - strand, within HGI48_RS13990 at 3130.858 kb on - strand at 3130.931 kb on + strand at 3130.931 kb on + strand at 3130.932 kb on - strand, within HGI48_RS13990 at 3130.934 kb on + strand, within HGI48_RS13990 at 3130.964 kb on + strand at 3130.965 kb on - strand, within HGI48_RS13990 at 3131.029 kb on + strand at 3131.042 kb on + strand at 3131.042 kb on + strand at 3131.042 kb on + strand at 3131.043 kb on - strand at 3131.043 kb on - strand at 3131.046 kb on + strand at 3131.046 kb on + strand at 3131.127 kb on + strand at 3131.129 kb on + strand at 3131.140 kb on + strand at 3131.193 kb on + strand, within HGI48_RS13995 at 3131.193 kb on + strand, within HGI48_RS13995 at 3131.193 kb on + strand, within HGI48_RS13995 at 3131.350 kb on + strand at 3131.350 kb on + strand at 3131.351 kb on - strand at 3131.362 kb on + strand at 3131.362 kb on + strand at 3131.365 kb on + strand at 3131.365 kb on + strand at 3131.365 kb on + strand at 3131.366 kb on - strand at 3131.366 kb on - strand at 3131.366 kb on - strand at 3131.366 kb on - strand at 3131.366 kb on - strand at 3131.409 kb on - strand at 3131.409 kb on - strand at 3131.457 kb on + strand at 3131.473 kb on + strand at 3131.486 kb on - strand at 3131.486 kb on - strand at 3131.486 kb on - strand at 3131.529 kb on - strand at 3131.540 kb on - strand at 3131.546 kb on + strand at 3131.547 kb on - strand at 3131.547 kb on - strand at 3131.572 kb on + strand at 3131.572 kb on + strand at 3131.572 kb on + strand at 3131.573 kb on - strand at 3131.578 kb on + strand at 3131.579 kb on - strand at 3131.582 kb on + strand at 3131.583 kb on - strand at 3131.583 kb on - strand at 3131.583 kb on - strand at 3131.589 kb on - strand at 3131.643 kb on + strand at 3131.643 kb on + strand at 3131.678 kb on + strand at 3131.679 kb on - strand at 3131.679 kb on - strand at 3131.777 kb on + strand at 3131.777 kb on + strand at 3131.777 kb on + strand, within HGI48_RS14000 at 3131.879 kb on + strand, within HGI48_RS14000 at 3131.880 kb on - strand, within HGI48_RS14000 at 3131.966 kb on + strand, within HGI48_RS14000 at 3131.966 kb on + strand, within HGI48_RS14000 at 3131.966 kb on + strand, within HGI48_RS14000 at 3131.967 kb on - strand, within HGI48_RS14000 at 3131.967 kb on - strand, within HGI48_RS14000 at 3131.967 kb on - strand, within HGI48_RS14000 at 3131.967 kb on - strand, within HGI48_RS14000 at 3132.010 kb on + strand, within HGI48_RS14000 at 3132.096 kb on + strand at 3132.096 kb on + strand, within HGI48_RS14000 at 3132.097 kb on - strand at 3132.188 kb on + strand at 3132.189 kb on - strand, within HGI48_RS14000 at 3132.217 kb on + strand, within HGI48_RS14000 at 3132.442 kb on + strand, within HGI48_RS14000 at 3132.442 kb on + strand, within HGI48_RS14000 at 3132.443 kb on - strand, within HGI48_RS14000 at 3132.446 kb on + strand, within HGI48_RS14000 at 3132.446 kb on + strand, within HGI48_RS14000 at 3132.446 kb on + strand, within HGI48_RS14000 at 3132.447 kb on - strand, within HGI48_RS14000 at 3132.447 kb on - strand, within HGI48_RS14000 at 3132.447 kb on - strand, within HGI48_RS14000 at 3132.479 kb on - strand, within HGI48_RS14000 at 3132.493 kb on - strand, within HGI48_RS14000 at 3132.493 kb on - strand, within HGI48_RS14000 at 3132.493 kb on - strand, within HGI48_RS14000 at 3132.584 kb on - strand at 3132.601 kb on + strand at 3132.602 kb on - strand at 3132.620 kb on - strand at 3132.669 kb on - strand at 3132.678 kb on + strand at 3132.678 kb on + strand at 3132.678 kb on + strand at 3132.678 kb on + strand at 3132.679 kb on - strand at 3132.891 kb on + strand, within HGI48_RS14005 at 3132.891 kb on + strand, within HGI48_RS14005 at 3132.891 kb on + strand, within HGI48_RS14005 at 3132.893 kb on + strand at 3132.893 kb on + strand, within HGI48_RS14005 at 3132.893 kb on + strand, within HGI48_RS14005 at 3132.893 kb on + strand, within HGI48_RS14005 at 3132.893 kb on + strand, within HGI48_RS14005 at 3132.893 kb on + strand, within HGI48_RS14005 at 3132.893 kb on + strand, within HGI48_RS14005 at 3132.894 kb on - strand, within HGI48_RS14005 at 3132.894 kb on - strand, within HGI48_RS14005 at 3132.894 kb on - strand, within HGI48_RS14005 at 3132.894 kb on - strand at 3132.923 kb on + strand, within HGI48_RS14005 at 3132.923 kb on + strand, within HGI48_RS14005 at 3132.923 kb on + strand, within HGI48_RS14005 at 3132.924 kb on - strand, within HGI48_RS14005 at 3132.924 kb on - strand, within HGI48_RS14005 at 3132.924 kb on - strand at 3132.924 kb on - strand, within HGI48_RS14005 at 3132.924 kb on - strand, within HGI48_RS14005 at 3132.924 kb on - strand, within HGI48_RS14005 at 3132.927 kb on + strand, within HGI48_RS14005 at 3132.927 kb on + strand, within HGI48_RS14005 at 3132.928 kb on - strand, within HGI48_RS14005 at 3132.940 kb on + strand, within HGI48_RS14005 at 3133.005 kb on + strand, within HGI48_RS14005 at 3133.005 kb on + strand, within HGI48_RS14005 at 3133.005 kb on + strand at 3133.006 kb on - strand at 3133.006 kb on - strand, within HGI48_RS14005 at 3133.006 kb on - strand at 3133.008 kb on + strand, within HGI48_RS14005 at 3133.008 kb on + strand, within HGI48_RS14005 at 3133.008 kb on + strand, within HGI48_RS14005 at 3133.119 kb on + strand, within HGI48_RS14005 at 3133.119 kb on + strand, within HGI48_RS14005 at 3133.192 kb on - strand, within HGI48_RS14005 at 3133.195 kb on - strand, within HGI48_RS14005 at 3133.195 kb on - strand, within HGI48_RS14005 at 3133.197 kb on + strand, within HGI48_RS14005 at 3133.198 kb on - strand, within HGI48_RS14005 at 3133.198 kb on - strand, within HGI48_RS14005 at 3133.198 kb on - strand at 3133.293 kb on + strand, within HGI48_RS14005 at 3133.324 kb on + strand, within HGI48_RS14005 at 3133.324 kb on + strand, within HGI48_RS14005 at 3133.325 kb on - strand, within HGI48_RS14005 at 3133.325 kb on - strand, within HGI48_RS14005 at 3133.325 kb on - strand, within HGI48_RS14005 at 3133.425 kb on + strand at 3133.449 kb on + strand at 3133.449 kb on + strand at 3133.449 kb on + strand at 3133.450 kb on - strand at 3133.450 kb on - strand at 3133.450 kb on - strand at 3133.450 kb on - strand at 3133.450 kb on - strand at 3133.450 kb on - strand at 3133.463 kb on + strand at 3133.464 kb on - strand at 3133.466 kb on + strand at 3133.498 kb on + strand at 3133.498 kb on + strand at 3133.498 kb on + strand at 3133.499 kb on - strand at 3133.499 kb on - strand at 3133.502 kb on + strand at 3133.502 kb on + strand at 3133.503 kb on - strand at 3133.503 kb on - strand at 3133.503 kb on - strand at 3133.503 kb on - strand at 3133.526 kb on - strand at 3133.526 kb on - strand at 3133.561 kb on + strand at 3133.561 kb on + strand at 3133.561 kb on + strand at 3133.561 kb on + strand at 3133.582 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 3,130,605 + +0.0 3,130,605 + -2.1 3,130,624 + +0.7 3,130,624 + -0.4 3,130,625 - +0.3 3,130,626 + +1.3 3,130,626 + +1.0 3,130,626 + +0.3 3,130,626 + -0.8 3,130,626 + -1.3 3,130,626 + -0.8 3,130,626 + +1.5 3,130,626 + +0.3 3,130,627 - +1.0 3,130,627 - +1.2 3,130,627 - +1.7 3,130,627 - -1.0 3,130,627 - -1.2 3,130,627 - -2.3 3,130,628 + +1.3 3,130,628 + -0.1 3,130,628 + +1.0 3,130,628 + -1.5 3,130,628 + +0.2 3,130,628 + -0.5 3,130,628 + -0.1 3,130,629 - -1.1 3,130,629 - -1.7 3,130,629 - +0.3 3,130,668 + HGI48_RS13990 0.17 +0.3 3,130,668 + +0.5 3,130,668 + HGI48_RS13990 0.17 +0.7 3,130,668 + HGI48_RS13990 0.17 +0.2 3,130,669 - HGI48_RS13990 0.17 +0.1 3,130,669 - HGI48_RS13990 0.17 -1.4 3,130,669 - HGI48_RS13990 0.17 +0.2 3,130,670 + HGI48_RS13990 0.17 +0.2 3,130,671 - HGI48_RS13990 0.18 +1.5 3,130,671 - HGI48_RS13990 0.18 +0.1 3,130,683 + HGI48_RS13990 0.20 +2.7 3,130,683 + HGI48_RS13990 0.20 -0.7 3,130,683 + HGI48_RS13990 0.20 +1.5 3,130,684 - HGI48_RS13990 0.21 -0.5 3,130,688 - HGI48_RS13990 0.21 +0.5 3,130,688 - HGI48_RS13990 0.21 -1.8 3,130,712 + HGI48_RS13990 0.27 -0.3 3,130,712 + HGI48_RS13990 0.27 +0.1 3,130,713 - HGI48_RS13990 0.27 -0.7 3,130,822 - HGI48_RS13990 0.52 +1.2 3,130,857 + HGI48_RS13990 0.60 -2.7 3,130,857 + HGI48_RS13990 0.60 +0.0 3,130,857 + HGI48_RS13990 0.60 +1.1 3,130,857 + HGI48_RS13990 0.60 -0.2 3,130,858 - HGI48_RS13990 0.60 -0.3 3,130,858 - HGI48_RS13990 0.60 -0.8 3,130,858 - HGI48_RS13990 0.60 -0.6 3,130,858 - HGI48_RS13990 0.60 -1.1 3,130,858 - HGI48_RS13990 0.60 -0.6 3,130,858 - -1.1 3,130,931 + +2.3 3,130,931 + +0.5 3,130,932 - HGI48_RS13990 0.77 -0.7 3,130,934 + HGI48_RS13990 0.78 +0.5 3,130,964 + +0.9 3,130,965 - HGI48_RS13990 0.85 -0.1 3,131,029 + -0.8 3,131,042 + -2.5 3,131,042 + -1.1 3,131,042 + -0.3 3,131,043 - +0.5 3,131,043 - -0.2 3,131,046 + -0.7 3,131,046 + +0.8 3,131,127 + -0.5 3,131,129 + -0.4 3,131,140 + +0.9 3,131,193 + HGI48_RS13995 0.21 +0.5 3,131,193 + HGI48_RS13995 0.21 -0.9 3,131,193 + HGI48_RS13995 0.21 -0.1 3,131,350 + +0.3 3,131,350 + -0.8 3,131,351 - -0.5 3,131,362 + -1.0 3,131,362 + +1.2 3,131,365 + -1.5 3,131,365 + +0.9 3,131,365 + -0.1 3,131,366 - +0.8 3,131,366 - -1.1 3,131,366 - +0.5 3,131,366 - +0.9 3,131,366 - +1.8 3,131,409 - -0.1 3,131,409 - -0.8 3,131,457 + +0.1 3,131,473 + +2.5 3,131,486 - +0.3 3,131,486 - +0.4 3,131,486 - -0.0 3,131,529 - +0.4 3,131,540 - -0.3 3,131,546 + -1.8 3,131,547 - +0.2 3,131,547 - -0.1 3,131,572 + -1.8 3,131,572 + -2.1 3,131,572 + +0.8 3,131,573 - +0.2 3,131,578 + +0.9 3,131,579 - +0.4 3,131,582 + -0.3 3,131,583 - -0.1 3,131,583 - +0.9 3,131,583 - -0.5 3,131,589 - -1.8 3,131,643 + +1.1 3,131,643 + +0.5 3,131,678 + -1.3 3,131,679 - -0.4 3,131,679 - -0.8 3,131,777 + +1.9 3,131,777 + +1.7 3,131,777 + HGI48_RS14000 0.18 -0.2 3,131,879 + HGI48_RS14000 0.28 -0.5 3,131,880 - HGI48_RS14000 0.28 +0.9 3,131,966 + HGI48_RS14000 0.37 -0.9 3,131,966 + HGI48_RS14000 0.37 +0.1 3,131,966 + HGI48_RS14000 0.37 -1.3 3,131,967 - HGI48_RS14000 0.37 +0.3 3,131,967 - HGI48_RS14000 0.37 -0.7 3,131,967 - HGI48_RS14000 0.37 +0.3 3,131,967 - HGI48_RS14000 0.37 +0.8 3,132,010 + HGI48_RS14000 0.41 +0.3 3,132,096 + +1.8 3,132,096 + HGI48_RS14000 0.50 -0.6 3,132,097 - +2.5 3,132,188 + -0.5 3,132,189 - HGI48_RS14000 0.59 +0.2 3,132,217 + HGI48_RS14000 0.61 +0.2 3,132,442 + HGI48_RS14000 0.83 -0.0 3,132,442 + HGI48_RS14000 0.83 +0.5 3,132,443 - HGI48_RS14000 0.84 +0.5 3,132,446 + HGI48_RS14000 0.84 +0.6 3,132,446 + HGI48_RS14000 0.84 -3.5 3,132,446 + HGI48_RS14000 0.84 -0.2 3,132,447 - HGI48_RS14000 0.84 +1.2 3,132,447 - HGI48_RS14000 0.84 +0.2 3,132,447 - HGI48_RS14000 0.84 +0.5 3,132,479 - HGI48_RS14000 0.87 -0.8 3,132,493 - HGI48_RS14000 0.88 +1.6 3,132,493 - HGI48_RS14000 0.88 +0.0 3,132,493 - HGI48_RS14000 0.88 -0.2 3,132,584 - -0.8 3,132,601 + +0.1 3,132,602 - -1.8 3,132,620 - +1.6 3,132,669 - +0.1 3,132,678 + +2.2 3,132,678 + -1.0 3,132,678 + +1.1 3,132,678 + -0.2 3,132,679 - -2.3 3,132,891 + HGI48_RS14005 0.29 +0.3 3,132,891 + HGI48_RS14005 0.29 +0.2 3,132,891 + HGI48_RS14005 0.29 -0.3 3,132,893 + +1.5 3,132,893 + HGI48_RS14005 0.29 -0.9 3,132,893 + HGI48_RS14005 0.29 -0.2 3,132,893 + HGI48_RS14005 0.29 -0.1 3,132,893 + HGI48_RS14005 0.29 -0.6 3,132,893 + HGI48_RS14005 0.29 +0.3 3,132,893 + HGI48_RS14005 0.29 +0.6 3,132,894 - HGI48_RS14005 0.29 -2.1 3,132,894 - HGI48_RS14005 0.29 +1.5 3,132,894 - HGI48_RS14005 0.29 +0.0 3,132,894 - +0.9 3,132,923 + HGI48_RS14005 0.33 -1.5 3,132,923 + HGI48_RS14005 0.33 -0.5 3,132,923 + HGI48_RS14005 0.33 -0.8 3,132,924 - HGI48_RS14005 0.33 +0.6 3,132,924 - HGI48_RS14005 0.33 +0.3 3,132,924 - -1.1 3,132,924 - HGI48_RS14005 0.33 -1.5 3,132,924 - HGI48_RS14005 0.33 -2.3 3,132,924 - HGI48_RS14005 0.33 -0.6 3,132,927 + HGI48_RS14005 0.33 -0.4 3,132,927 + HGI48_RS14005 0.33 -0.1 3,132,928 - HGI48_RS14005 0.33 +0.1 3,132,940 + HGI48_RS14005 0.35 -1.8 3,133,005 + HGI48_RS14005 0.43 -3.3 3,133,005 + HGI48_RS14005 0.43 -0.1 3,133,005 + -1.1 3,133,006 - -1.1 3,133,006 - HGI48_RS14005 0.43 -0.5 3,133,006 - -1.1 3,133,008 + HGI48_RS14005 0.44 +0.5 3,133,008 + HGI48_RS14005 0.44 -0.6 3,133,008 + HGI48_RS14005 0.44 -0.2 3,133,119 + HGI48_RS14005 0.58 -1.8 3,133,119 + HGI48_RS14005 0.58 -1.5 3,133,192 - HGI48_RS14005 0.67 +0.8 3,133,195 - HGI48_RS14005 0.67 -1.5 3,133,195 - HGI48_RS14005 0.67 -0.2 3,133,197 + HGI48_RS14005 0.68 -1.5 3,133,198 - HGI48_RS14005 0.68 -0.4 3,133,198 - HGI48_RS14005 0.68 -0.5 3,133,198 - +2.1 3,133,293 + HGI48_RS14005 0.80 +0.3 3,133,324 + HGI48_RS14005 0.84 -0.7 3,133,324 + HGI48_RS14005 0.84 +0.4 3,133,325 - HGI48_RS14005 0.84 -0.2 3,133,325 - HGI48_RS14005 0.84 +0.9 3,133,325 - HGI48_RS14005 0.84 -0.2 3,133,425 + -0.4 3,133,449 + -1.0 3,133,449 + -0.7 3,133,449 + -1.7 3,133,450 - -0.1 3,133,450 - +1.7 3,133,450 - -0.5 3,133,450 - -0.3 3,133,450 - -0.7 3,133,450 - -0.6 3,133,463 + +0.4 3,133,464 - -1.5 3,133,466 + +0.8 3,133,498 + +1.8 3,133,498 + -1.5 3,133,498 + -0.1 3,133,499 - +0.3 3,133,499 - -0.1 3,133,502 + +0.1 3,133,502 + -0.5 3,133,503 - -0.7 3,133,503 - +0.7 3,133,503 - +1.7 3,133,503 - -1.5 3,133,526 - +0.1 3,133,526 - +2.2 3,133,561 + +0.2 3,133,561 + +1.6 3,133,561 + -0.3 3,133,561 + -3.5 3,133,582 + +0.5
Or see this region's nucleotide sequence