Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt HGI48_RS05690 and HGI48_RS05695 are separated by 188 nucleotides HGI48_RS05695 and HGI48_RS05700 are separated by 194 nucleotides HGI48_RS05700 and HGI48_RS05705 are separated by 255 nucleotides
HGI48_RS05690: HGI48_RS05690 - ATP-dependent protease ATP-binding subunit ClpX, at 1,198,812 to 1,200,086
_RS05690
HGI48_RS05695: HGI48_RS05695 - endopeptidase La, at 1,200,275 to 1,202,638
_RS05695
HGI48_RS05700: HGI48_RS05700 - DNA-binding protein HU-beta, at 1,202,833 to 1,203,105
_RS05700
HGI48_RS05705: HGI48_RS05705 - peptidylprolyl isomerase, at 1,203,361 to 1,205,241
_RS05705
Position (kb)
1200
1201
1202
1203 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3
4 at 1199.355 kb on + strand, within HGI48_RS05690 at 1199.356 kb on - strand, within HGI48_RS05690 at 1199.938 kb on + strand, within HGI48_RS05690 at 1200.174 kb on + strand at 1200.175 kb on - strand at 1200.175 kb on - strand at 1200.178 kb on + strand at 1200.187 kb on - strand at 1200.187 kb on - strand at 1200.188 kb on + strand at 1200.188 kb on + strand at 1200.196 kb on + strand at 1200.200 kb on + strand at 1200.201 kb on - strand at 1200.202 kb on + strand at 1200.261 kb on + strand at 1200.261 kb on + strand at 1200.275 kb on - strand at 1200.300 kb on + strand at 1200.301 kb on - strand at 1200.313 kb on - strand at 1200.503 kb on - strand at 1200.693 kb on + strand, within HGI48_RS05695 at 1200.695 kb on + strand, within HGI48_RS05695 at 1200.696 kb on - strand, within HGI48_RS05695 at 1200.729 kb on + strand, within HGI48_RS05695 at 1200.730 kb on - strand, within HGI48_RS05695 at 1200.742 kb on + strand, within HGI48_RS05695 at 1200.748 kb on + strand, within HGI48_RS05695 at 1200.894 kb on + strand, within HGI48_RS05695 at 1200.960 kb on - strand, within HGI48_RS05695 at 1201.111 kb on + strand, within HGI48_RS05695 at 1201.154 kb on + strand, within HGI48_RS05695 at 1201.155 kb on - strand, within HGI48_RS05695 at 1201.155 kb on - strand, within HGI48_RS05695 at 1201.155 kb on - strand, within HGI48_RS05695 at 1201.177 kb on - strand at 1201.274 kb on - strand, within HGI48_RS05695 at 1201.274 kb on - strand, within HGI48_RS05695 at 1201.399 kb on + strand, within HGI48_RS05695 at 1201.403 kb on + strand, within HGI48_RS05695 at 1201.403 kb on + strand at 1201.403 kb on + strand, within HGI48_RS05695 at 1201.404 kb on - strand, within HGI48_RS05695 at 1201.404 kb on - strand, within HGI48_RS05695 at 1201.404 kb on - strand, within HGI48_RS05695 at 1201.466 kb on + strand, within HGI48_RS05695 at 1201.466 kb on + strand, within HGI48_RS05695 at 1201.467 kb on - strand, within HGI48_RS05695 at 1201.467 kb on - strand, within HGI48_RS05695 at 1201.467 kb on - strand, within HGI48_RS05695 at 1201.467 kb on - strand, within HGI48_RS05695 at 1201.640 kb on + strand, within HGI48_RS05695 at 1201.656 kb on - strand, within HGI48_RS05695 at 1201.656 kb on - strand, within HGI48_RS05695 at 1201.754 kb on - strand, within HGI48_RS05695 at 1201.874 kb on + strand at 1201.877 kb on + strand, within HGI48_RS05695 at 1201.878 kb on - strand, within HGI48_RS05695 at 1201.878 kb on - strand, within HGI48_RS05695 at 1201.878 kb on - strand, within HGI48_RS05695 at 1201.934 kb on - strand, within HGI48_RS05695 at 1201.975 kb on + strand at 1201.976 kb on - strand, within HGI48_RS05695 at 1201.976 kb on - strand, within HGI48_RS05695 at 1202.007 kb on - strand, within HGI48_RS05695 at 1202.007 kb on - strand, within HGI48_RS05695 at 1202.007 kb on - strand, within HGI48_RS05695 at 1202.007 kb on - strand, within HGI48_RS05695 at 1202.007 kb on - strand at 1202.010 kb on + strand, within HGI48_RS05695 at 1202.011 kb on - strand, within HGI48_RS05695 at 1202.011 kb on - strand at 1202.150 kb on + strand, within HGI48_RS05695 at 1202.150 kb on + strand, within HGI48_RS05695 at 1202.151 kb on - strand, within HGI48_RS05695 at 1202.151 kb on - strand, within HGI48_RS05695 at 1202.151 kb on - strand, within HGI48_RS05695 at 1202.526 kb on + strand at 1202.527 kb on - strand at 1202.527 kb on - strand at 1202.575 kb on + strand at 1202.575 kb on + strand at 1202.575 kb on + strand at 1202.576 kb on - strand at 1202.576 kb on - strand at 1202.578 kb on + strand at 1202.579 kb on - strand at 1202.636 kb on + strand at 1202.716 kb on - strand at 1202.721 kb on - strand at 1202.752 kb on + strand at 1202.771 kb on + strand at 1202.777 kb on + strand at 1202.777 kb on + strand at 1202.778 kb on - strand at 1202.778 kb on - strand at 1202.778 kb on - strand at 1202.803 kb on + strand at 1202.807 kb on - strand at 1202.812 kb on + strand at 1202.813 kb on - strand at 1202.877 kb on + strand, within HGI48_RS05700 at 1202.878 kb on - strand, within HGI48_RS05700 at 1202.917 kb on - strand, within HGI48_RS05700 at 1203.015 kb on + strand, within HGI48_RS05700 at 1203.110 kb on + strand at 1203.110 kb on + strand at 1203.111 kb on - strand at 1203.111 kb on - strand at 1203.155 kb on + strand at 1203.155 kb on + strand at 1203.156 kb on - strand at 1203.156 kb on - strand at 1203.156 kb on - strand at 1203.180 kb on + strand at 1203.181 kb on + strand at 1203.181 kb on + strand at 1203.186 kb on + strand at 1203.186 kb on + strand at 1203.186 kb on + strand at 1203.186 kb on + strand at 1203.187 kb on - strand at 1203.188 kb on + strand at 1203.188 kb on + strand at 1203.188 kb on + strand at 1203.189 kb on - strand at 1203.189 kb on - strand at 1203.189 kb on - strand at 1203.189 kb on - strand at 1203.189 kb on - strand at 1203.204 kb on - strand at 1203.237 kb on + strand at 1203.237 kb on + strand at 1203.238 kb on - strand at 1203.238 kb on - strand at 1203.244 kb on - strand at 1203.254 kb on + strand at 1203.254 kb on + strand at 1203.284 kb on + strand at 1203.284 kb on + strand at 1203.285 kb on - strand at 1203.285 kb on - strand at 1203.285 kb on - strand at 1203.285 kb on - strand at 1203.339 kb on + strand at 1203.340 kb on - strand at 1203.360 kb on + strand at 1203.360 kb on + strand at 1203.361 kb on - strand at 1203.361 kb on - strand at 1203.361 kb on - strand at 1203.361 kb on - strand at 1203.374 kb on + strand at 1203.408 kb on + strand at 1203.409 kb on - strand at 1203.464 kb on + strand at 1203.465 kb on - strand at 1203.537 kb on - strand at 1203.607 kb on + strand, within HGI48_RS05705 at 1203.607 kb on + strand, within HGI48_RS05705 at 1203.607 kb on + strand, within HGI48_RS05705 at 1203.608 kb on - strand, within HGI48_RS05705 at 1203.608 kb on - strand, within HGI48_RS05705 at 1203.608 kb on - strand, within HGI48_RS05705 at 1203.608 kb on - strand, within HGI48_RS05705 at 1203.608 kb on - strand at 1203.609 kb on + strand, within HGI48_RS05705 at 1203.609 kb on + strand, within HGI48_RS05705 at 1203.609 kb on + strand, within HGI48_RS05705 at 1203.609 kb on + strand, within HGI48_RS05705 at 1203.610 kb on - strand at 1203.610 kb on - strand, within HGI48_RS05705 at 1203.610 kb on - strand at 1203.610 kb on - strand, within HGI48_RS05705 at 1203.610 kb on - strand, within HGI48_RS05705 at 1203.610 kb on - strand, within HGI48_RS05705 at 1203.610 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 1,199,355 + HGI48_RS05690 0.43 -1.4 1,199,356 - HGI48_RS05690 0.43 -0.4 1,199,938 + HGI48_RS05690 0.88 -1.8 1,200,174 + +0.6 1,200,175 - -0.0 1,200,175 - -2.4 1,200,178 + +0.9 1,200,187 - +0.6 1,200,187 - -1.8 1,200,188 + +0.8 1,200,188 + +0.6 1,200,196 + +0.0 1,200,200 + -1.1 1,200,201 - +0.6 1,200,202 + +1.7 1,200,261 + +1.7 1,200,261 + +3.0 1,200,275 - -0.2 1,200,300 + +1.7 1,200,301 - -1.6 1,200,313 - -1.8 1,200,503 - +1.2 1,200,693 + HGI48_RS05695 0.18 +1.1 1,200,695 + HGI48_RS05695 0.18 +0.8 1,200,696 - HGI48_RS05695 0.18 +0.4 1,200,729 + HGI48_RS05695 0.19 +2.6 1,200,730 - HGI48_RS05695 0.19 +0.6 1,200,742 + HGI48_RS05695 0.20 +1.0 1,200,748 + HGI48_RS05695 0.20 +1.0 1,200,894 + HGI48_RS05695 0.26 +1.7 1,200,960 - HGI48_RS05695 0.29 +0.8 1,201,111 + HGI48_RS05695 0.35 +0.9 1,201,154 + HGI48_RS05695 0.37 +1.6 1,201,155 - HGI48_RS05695 0.37 +1.2 1,201,155 - HGI48_RS05695 0.37 -1.4 1,201,155 - HGI48_RS05695 0.37 +1.3 1,201,177 - +2.7 1,201,274 - HGI48_RS05695 0.42 +3.6 1,201,274 - HGI48_RS05695 0.42 -0.4 1,201,399 + HGI48_RS05695 0.48 +0.1 1,201,403 + HGI48_RS05695 0.48 +1.8 1,201,403 + +2.4 1,201,403 + HGI48_RS05695 0.48 +0.6 1,201,404 - HGI48_RS05695 0.48 -1.2 1,201,404 - HGI48_RS05695 0.48 +1.8 1,201,404 - HGI48_RS05695 0.48 +1.8 1,201,466 + HGI48_RS05695 0.50 +2.5 1,201,466 + HGI48_RS05695 0.50 +1.2 1,201,467 - HGI48_RS05695 0.50 +0.3 1,201,467 - HGI48_RS05695 0.50 -0.7 1,201,467 - HGI48_RS05695 0.50 -2.0 1,201,467 - HGI48_RS05695 0.50 +0.7 1,201,640 + HGI48_RS05695 0.58 -0.7 1,201,656 - HGI48_RS05695 0.58 +1.6 1,201,656 - HGI48_RS05695 0.58 -0.7 1,201,754 - HGI48_RS05695 0.63 +1.8 1,201,874 + +1.0 1,201,877 + HGI48_RS05695 0.68 +1.6 1,201,878 - HGI48_RS05695 0.68 +1.2 1,201,878 - HGI48_RS05695 0.68 -1.4 1,201,878 - HGI48_RS05695 0.68 +2.2 1,201,934 - HGI48_RS05695 0.70 +0.2 1,201,975 + +2.1 1,201,976 - HGI48_RS05695 0.72 -1.4 1,201,976 - HGI48_RS05695 0.72 +2.2 1,202,007 - HGI48_RS05695 0.73 +0.1 1,202,007 - HGI48_RS05695 0.73 +1.2 1,202,007 - HGI48_RS05695 0.73 +1.1 1,202,007 - HGI48_RS05695 0.73 -0.8 1,202,007 - +4.6 1,202,010 + HGI48_RS05695 0.73 -1.0 1,202,011 - HGI48_RS05695 0.73 +0.7 1,202,011 - +3.1 1,202,150 + HGI48_RS05695 0.79 +2.6 1,202,150 + HGI48_RS05695 0.79 +1.3 1,202,151 - HGI48_RS05695 0.79 -1.2 1,202,151 - HGI48_RS05695 0.79 +1.8 1,202,151 - HGI48_RS05695 0.79 +0.1 1,202,526 + -0.4 1,202,527 - +1.1 1,202,527 - -1.0 1,202,575 + +1.7 1,202,575 + -2.4 1,202,575 + +1.8 1,202,576 - +1.8 1,202,576 - -1.4 1,202,578 + +1.5 1,202,579 - +0.8 1,202,636 + +1.6 1,202,716 - -0.7 1,202,721 - -1.4 1,202,752 + -0.9 1,202,771 + -2.2 1,202,777 + +0.1 1,202,777 + -0.0 1,202,778 - -2.6 1,202,778 - -1.0 1,202,778 - +1.3 1,202,803 + +1.0 1,202,807 - -1.4 1,202,812 + -0.0 1,202,813 - +0.4 1,202,877 + HGI48_RS05700 0.16 -1.2 1,202,878 - HGI48_RS05700 0.16 -3.3 1,202,917 - HGI48_RS05700 0.31 +1.1 1,203,015 + HGI48_RS05700 0.67 -0.1 1,203,110 + +0.6 1,203,110 + -1.4 1,203,111 - -0.9 1,203,111 - -0.4 1,203,155 + -1.2 1,203,155 + +1.3 1,203,156 - -0.8 1,203,156 - -1.2 1,203,156 - -2.2 1,203,180 + +1.0 1,203,181 + +0.3 1,203,181 + -0.0 1,203,186 + +0.1 1,203,186 + +0.8 1,203,186 + -0.4 1,203,186 + -1.2 1,203,187 - -2.1 1,203,188 + +0.9 1,203,188 + -1.2 1,203,188 + -0.6 1,203,189 - -1.8 1,203,189 - -0.0 1,203,189 - -1.8 1,203,189 - +0.3 1,203,189 - -1.9 1,203,204 - +0.3 1,203,237 + -1.2 1,203,237 + +0.3 1,203,238 - +0.1 1,203,238 - -0.7 1,203,244 - -0.1 1,203,254 + +0.3 1,203,254 + -1.8 1,203,284 + +1.3 1,203,284 + -0.4 1,203,285 - -1.9 1,203,285 - +2.0 1,203,285 - -0.7 1,203,285 - -1.7 1,203,339 + +1.1 1,203,340 - -0.2 1,203,360 + +1.6 1,203,360 + -0.8 1,203,361 - -1.7 1,203,361 - -0.2 1,203,361 - -0.1 1,203,361 - +0.1 1,203,374 + -2.9 1,203,408 + +0.2 1,203,409 - -1.8 1,203,464 + -1.0 1,203,465 - +0.8 1,203,537 - -1.1 1,203,607 + HGI48_RS05705 0.13 -2.0 1,203,607 + HGI48_RS05705 0.13 -1.4 1,203,607 + HGI48_RS05705 0.13 +0.1 1,203,608 - HGI48_RS05705 0.13 -0.8 1,203,608 - HGI48_RS05705 0.13 -0.3 1,203,608 - HGI48_RS05705 0.13 +0.8 1,203,608 - HGI48_RS05705 0.13 -0.4 1,203,608 - +1.6 1,203,609 + HGI48_RS05705 0.13 +0.8 1,203,609 + HGI48_RS05705 0.13 -0.1 1,203,609 + HGI48_RS05705 0.13 +1.0 1,203,609 + HGI48_RS05705 0.13 -1.4 1,203,610 - -1.0 1,203,610 - HGI48_RS05705 0.13 -0.2 1,203,610 - +1.3 1,203,610 - HGI48_RS05705 0.13 -1.4 1,203,610 - HGI48_RS05705 0.13 -0.4 1,203,610 - HGI48_RS05705 0.13 -1.2 1,203,610 - +0.6
Or see this region's nucleotide sequence