Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt DDA3937_RS00560 and DDA3937_RS00565 are separated by 228 nucleotides DDA3937_RS00565 and DDA3937_RS00570 are separated by 18 nucleotides DDA3937_RS00570 and DDA3937_RS21740 overlap by 16 nucleotides DDA3937_RS21740 and DDA3937_RS00575 are separated by 68 nucleotides
DDA3937_RS00560: DDA3937_RS00560 - insulinase family protein, at 134,031 to 135,494
_RS00560
DDA3937_RS00565: DDA3937_RS00565 - virulence RhuM family protein, at 135,723 to 136,748
_RS00565
DDA3937_RS00570: DDA3937_RS00570 - hypothetical protein, at 136,767 to 137,036
_RS00570
DDA3937_RS21740: DDA3937_RS21740 - type I restriction-modification system subunit M N-terminal domain-containing protein, at 137,021 to 137,359
_RS21740
DDA3937_RS00575: DDA3937_RS00575 - type II toxin-antitoxin system RelB/DinJ family antitoxin, at 137,428 to 137,928
_RS00575
Position (kb) 135
136
137 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3
4 at 134.955 kb on - strand, within DDA3937_RS00560 at 135.021 kb on + strand, within DDA3937_RS00560 at 135.022 kb on - strand, within DDA3937_RS00560 at 135.204 kb on + strand, within DDA3937_RS00560 at 135.204 kb on + strand, within DDA3937_RS00560 at 135.204 kb on + strand, within DDA3937_RS00560 at 135.205 kb on - strand, within DDA3937_RS00560 at 135.205 kb on - strand, within DDA3937_RS00560 at 135.309 kb on + strand, within DDA3937_RS00560 at 135.309 kb on + strand, within DDA3937_RS00560 at 135.309 kb on + strand, within DDA3937_RS00560 at 135.389 kb on - strand at 135.389 kb on - strand at 135.417 kb on - strand at 135.417 kb on - strand at 135.438 kb on + strand at 135.438 kb on + strand at 135.439 kb on - strand at 135.439 kb on - strand at 135.439 kb on - strand at 135.439 kb on - strand at 135.439 kb on - strand at 135.492 kb on + strand at 135.492 kb on + strand at 135.492 kb on + strand at 135.492 kb on + strand at 135.493 kb on - strand at 135.493 kb on - strand at 135.493 kb on - strand at 135.496 kb on + strand at 135.496 kb on + strand at 135.496 kb on + strand at 135.496 kb on + strand at 135.496 kb on + strand at 135.496 kb on + strand at 135.496 kb on + strand at 135.497 kb on - strand at 135.497 kb on - strand at 135.497 kb on - strand at 135.497 kb on - strand at 135.497 kb on - strand at 135.515 kb on - strand at 135.556 kb on + strand at 135.556 kb on + strand at 135.557 kb on - strand at 135.557 kb on - strand at 135.557 kb on - strand at 135.562 kb on + strand at 135.563 kb on - strand at 135.573 kb on + strand at 135.573 kb on + strand at 135.574 kb on - strand at 135.608 kb on - strand at 135.622 kb on + strand at 135.622 kb on + strand at 135.622 kb on + strand at 135.623 kb on - strand at 135.623 kb on - strand at 135.643 kb on + strand at 135.655 kb on + strand at 135.716 kb on + strand at 135.724 kb on + strand at 135.725 kb on - strand at 135.737 kb on + strand at 135.737 kb on + strand at 135.738 kb on - strand at 135.738 kb on - strand at 135.741 kb on + strand at 135.742 kb on - strand at 135.759 kb on + strand at 135.759 kb on + strand at 135.759 kb on + strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.760 kb on - strand at 135.894 kb on - strand, within DDA3937_RS00565 at 135.939 kb on + strand, within DDA3937_RS00565 at 135.939 kb on + strand, within DDA3937_RS00565 at 135.940 kb on - strand, within DDA3937_RS00565 at 135.940 kb on - strand, within DDA3937_RS00565 at 135.940 kb on - strand, within DDA3937_RS00565 at 135.986 kb on + strand, within DDA3937_RS00565 at 135.986 kb on + strand, within DDA3937_RS00565 at 135.987 kb on - strand, within DDA3937_RS00565 at 135.987 kb on - strand, within DDA3937_RS00565 at 136.031 kb on - strand, within DDA3937_RS00565 at 136.031 kb on - strand, within DDA3937_RS00565 at 136.031 kb on - strand, within DDA3937_RS00565 at 136.062 kb on + strand, within DDA3937_RS00565 at 136.062 kb on + strand, within DDA3937_RS00565 at 136.062 kb on + strand, within DDA3937_RS00565 at 136.062 kb on + strand, within DDA3937_RS00565 at 136.062 kb on + strand, within DDA3937_RS00565 at 136.063 kb on - strand, within DDA3937_RS00565 at 136.063 kb on - strand, within DDA3937_RS00565 at 136.063 kb on - strand, within DDA3937_RS00565 at 136.077 kb on - strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.078 kb on + strand, within DDA3937_RS00565 at 136.079 kb on - strand, within DDA3937_RS00565 at 136.145 kb on + strand, within DDA3937_RS00565 at 136.159 kb on + strand, within DDA3937_RS00565 at 136.159 kb on + strand, within DDA3937_RS00565 at 136.160 kb on - strand, within DDA3937_RS00565 at 136.235 kb on + strand, within DDA3937_RS00565 at 136.258 kb on + strand, within DDA3937_RS00565 at 136.398 kb on + strand, within DDA3937_RS00565 at 136.398 kb on + strand, within DDA3937_RS00565 at 136.464 kb on + strand, within DDA3937_RS00565 at 136.486 kb on + strand, within DDA3937_RS00565 at 136.498 kb on + strand, within DDA3937_RS00565 at 136.568 kb on + strand, within DDA3937_RS00565 at 136.583 kb on + strand, within DDA3937_RS00565 at 136.615 kb on + strand, within DDA3937_RS00565 at 136.615 kb on + strand, within DDA3937_RS00565 at 136.615 kb on + strand, within DDA3937_RS00565 at 136.617 kb on + strand, within DDA3937_RS00565 at 136.617 kb on + strand, within DDA3937_RS00565 at 136.617 kb on + strand, within DDA3937_RS00565 at 136.626 kb on + strand, within DDA3937_RS00565 at 136.626 kb on + strand, within DDA3937_RS00565 at 136.626 kb on + strand, within DDA3937_RS00565 at 136.626 kb on + strand, within DDA3937_RS00565 at 136.626 kb on + strand, within DDA3937_RS00565 at 136.626 kb on + strand, within DDA3937_RS00565 at 136.739 kb on + strand at 136.750 kb on + strand at 136.750 kb on + strand at 136.781 kb on + strand at 136.781 kb on + strand at 136.782 kb on - strand at 136.785 kb on - strand at 136.785 kb on - strand at 136.785 kb on - strand at 136.785 kb on - strand at 136.819 kb on + strand, within DDA3937_RS00570 at 136.819 kb on + strand, within DDA3937_RS00570 at 136.820 kb on - strand, within DDA3937_RS00570 at 136.820 kb on - strand, within DDA3937_RS00570 at 136.820 kb on - strand, within DDA3937_RS00570 at 136.820 kb on - strand, within DDA3937_RS00570 at 136.830 kb on + strand, within DDA3937_RS00570 at 136.831 kb on - strand, within DDA3937_RS00570 at 136.849 kb on - strand, within DDA3937_RS00570 at 136.849 kb on - strand, within DDA3937_RS00570 at 136.849 kb on - strand, within DDA3937_RS00570 at 136.853 kb on + strand, within DDA3937_RS00570 at 136.914 kb on + strand, within DDA3937_RS00570 at 136.915 kb on - strand, within DDA3937_RS00570 at 136.915 kb on - strand, within DDA3937_RS00570 at 136.915 kb on - strand, within DDA3937_RS00570 at 136.940 kb on + strand, within DDA3937_RS00570 at 136.941 kb on - strand, within DDA3937_RS00570 at 136.941 kb on - strand, within DDA3937_RS00570 at 137.044 kb on + strand at 137.044 kb on + strand at 137.044 kb on + strand at 137.045 kb on - strand at 137.045 kb on - strand at 137.045 kb on - strand at 137.045 kb on - strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.046 kb on + strand at 137.047 kb on - strand at 137.047 kb on - strand at 137.047 kb on - strand at 137.047 kb on - strand at 137.097 kb on + strand, within DDA3937_RS21740 at 137.107 kb on + strand, within DDA3937_RS21740 at 137.107 kb on + strand, within DDA3937_RS21740 at 137.107 kb on + strand, within DDA3937_RS21740 at 137.108 kb on - strand, within DDA3937_RS21740 at 137.108 kb on - strand, within DDA3937_RS21740 at 137.110 kb on + strand, within DDA3937_RS21740 at 137.110 kb on + strand, within DDA3937_RS21740 at 137.111 kb on - strand, within DDA3937_RS21740 at 137.111 kb on - strand, within DDA3937_RS21740 at 137.111 kb on - strand, within DDA3937_RS21740 at 137.112 kb on + strand, within DDA3937_RS21740 at 137.112 kb on + strand, within DDA3937_RS21740 at 137.112 kb on + strand, within DDA3937_RS21740 at 137.113 kb on - strand, within DDA3937_RS21740 at 137.113 kb on - strand, within DDA3937_RS21740 at 137.113 kb on - strand, within DDA3937_RS21740 at 137.181 kb on + strand, within DDA3937_RS21740 at 137.181 kb on + strand, within DDA3937_RS21740 at 137.182 kb on - strand, within DDA3937_RS21740 at 137.188 kb on + strand, within DDA3937_RS21740 at 137.189 kb on - strand, within DDA3937_RS21740 at 137.189 kb on - strand, within DDA3937_RS21740 at 137.189 kb on - strand, within DDA3937_RS21740 at 137.228 kb on - strand, within DDA3937_RS21740 at 137.234 kb on + strand, within DDA3937_RS21740 at 137.234 kb on + strand, within DDA3937_RS21740 at 137.234 kb on + strand, within DDA3937_RS21740 at 137.234 kb on + strand, within DDA3937_RS21740 at 137.234 kb on + strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.235 kb on - strand, within DDA3937_RS21740 at 137.237 kb on + strand, within DDA3937_RS21740 at 137.291 kb on + strand, within DDA3937_RS21740 at 137.291 kb on + strand, within DDA3937_RS21740 at 137.314 kb on + strand, within DDA3937_RS21740 at 137.315 kb on - strand, within DDA3937_RS21740 at 137.315 kb on - strand, within DDA3937_RS21740 at 137.400 kb on + strand at 137.429 kb on + strand at 137.429 kb on + strand at 137.448 kb on + strand at 137.449 kb on - strand at 137.677 kb on + strand, within DDA3937_RS00575
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 134,955 - DDA3937_RS00560 0.63 -1.1 135,021 + DDA3937_RS00560 0.68 -1.1 135,022 - DDA3937_RS00560 0.68 -1.1 135,204 + DDA3937_RS00560 0.80 -0.2 135,204 + DDA3937_RS00560 0.80 -3.1 135,204 + DDA3937_RS00560 0.80 -0.9 135,205 - DDA3937_RS00560 0.80 -0.8 135,205 - DDA3937_RS00560 0.80 -2.6 135,309 + DDA3937_RS00560 0.87 +1.3 135,309 + DDA3937_RS00560 0.87 -0.7 135,309 + DDA3937_RS00560 0.87 -1.4 135,389 - +2.9 135,389 - +2.7 135,417 - +0.2 135,417 - +2.1 135,438 + +0.5 135,438 + -0.7 135,439 - +1.3 135,439 - -0.1 135,439 - +0.2 135,439 - +1.2 135,439 - +0.7 135,492 + -0.5 135,492 + -1.4 135,492 + +1.3 135,492 + -3.0 135,493 - -0.2 135,493 - -3.3 135,493 - +0.9 135,496 + -0.7 135,496 + -0.6 135,496 + +0.4 135,496 + -1.0 135,496 + -1.1 135,496 + -1.4 135,496 + -1.3 135,497 - -1.6 135,497 - -0.9 135,497 - -0.2 135,497 - -3.0 135,497 - -0.7 135,515 - -1.5 135,556 + +2.1 135,556 + +3.2 135,557 - -2.0 135,557 - -2.6 135,557 - +1.8 135,562 + +0.5 135,563 - -2.8 135,573 + -2.7 135,573 + -1.1 135,574 - -1.1 135,608 - -0.0 135,622 + -2.1 135,622 + -1.2 135,622 + +0.9 135,623 - -1.2 135,623 - -2.1 135,643 + +2.4 135,655 + -1.2 135,716 + -0.5 135,724 + +0.7 135,725 - -1.2 135,737 + +1.8 135,737 + -0.7 135,738 - -0.2 135,738 - -1.6 135,741 + +0.5 135,742 - -1.1 135,759 + +0.1 135,759 + +3.8 135,759 + -1.5 135,760 - -2.0 135,760 - -0.6 135,760 - +0.4 135,760 - +0.2 135,760 - -1.2 135,760 - -2.1 135,760 - +0.6 135,760 - -0.5 135,894 - DDA3937_RS00565 0.17 -2.8 135,939 + DDA3937_RS00565 0.21 -1.1 135,939 + DDA3937_RS00565 0.21 -1.2 135,940 - DDA3937_RS00565 0.21 -1.2 135,940 - DDA3937_RS00565 0.21 -1.6 135,940 - DDA3937_RS00565 0.21 -0.4 135,986 + DDA3937_RS00565 0.26 -2.0 135,986 + DDA3937_RS00565 0.26 -2.2 135,987 - DDA3937_RS00565 0.26 -1.1 135,987 - DDA3937_RS00565 0.26 -0.2 136,031 - DDA3937_RS00565 0.30 -1.6 136,031 - DDA3937_RS00565 0.30 +0.1 136,031 - DDA3937_RS00565 0.30 -1.6 136,062 + DDA3937_RS00565 0.33 -1.1 136,062 + DDA3937_RS00565 0.33 -1.8 136,062 + DDA3937_RS00565 0.33 +0.9 136,062 + DDA3937_RS00565 0.33 +0.2 136,062 + DDA3937_RS00565 0.33 +1.1 136,063 - DDA3937_RS00565 0.33 -0.9 136,063 - DDA3937_RS00565 0.33 -0.1 136,063 - DDA3937_RS00565 0.33 +0.3 136,077 - DDA3937_RS00565 0.35 -1.1 136,078 + DDA3937_RS00565 0.35 +0.1 136,078 + DDA3937_RS00565 0.35 -1.4 136,078 + DDA3937_RS00565 0.35 -1.4 136,078 + DDA3937_RS00565 0.35 -0.7 136,078 + DDA3937_RS00565 0.35 -2.7 136,078 + DDA3937_RS00565 0.35 +1.1 136,078 + DDA3937_RS00565 0.35 -1.2 136,078 + DDA3937_RS00565 0.35 -0.7 136,078 + DDA3937_RS00565 0.35 -0.9 136,079 - DDA3937_RS00565 0.35 +1.4 136,145 + DDA3937_RS00565 0.41 -0.6 136,159 + DDA3937_RS00565 0.42 -0.5 136,159 + DDA3937_RS00565 0.42 +0.8 136,160 - DDA3937_RS00565 0.43 -1.7 136,235 + DDA3937_RS00565 0.50 -1.5 136,258 + DDA3937_RS00565 0.52 +0.1 136,398 + DDA3937_RS00565 0.66 +1.1 136,398 + DDA3937_RS00565 0.66 -0.9 136,464 + DDA3937_RS00565 0.72 +1.4 136,486 + DDA3937_RS00565 0.74 -0.0 136,498 + DDA3937_RS00565 0.76 +1.5 136,568 + DDA3937_RS00565 0.82 -0.5 136,583 + DDA3937_RS00565 0.84 +0.5 136,615 + DDA3937_RS00565 0.87 -1.6 136,615 + DDA3937_RS00565 0.87 -0.4 136,615 + DDA3937_RS00565 0.87 +1.5 136,617 + DDA3937_RS00565 0.87 -1.7 136,617 + DDA3937_RS00565 0.87 -0.4 136,617 + DDA3937_RS00565 0.87 -1.2 136,626 + DDA3937_RS00565 0.88 -1.7 136,626 + DDA3937_RS00565 0.88 -0.5 136,626 + DDA3937_RS00565 0.88 +0.3 136,626 + DDA3937_RS00565 0.88 -0.2 136,626 + DDA3937_RS00565 0.88 -0.1 136,626 + DDA3937_RS00565 0.88 -1.4 136,739 + +1.3 136,750 + -1.4 136,750 + +0.9 136,781 + -1.7 136,781 + -2.4 136,782 - -0.6 136,785 - -0.7 136,785 - +1.3 136,785 - +0.1 136,785 - -0.7 136,819 + DDA3937_RS00570 0.19 -2.4 136,819 + DDA3937_RS00570 0.19 +1.9 136,820 - DDA3937_RS00570 0.20 -0.7 136,820 - DDA3937_RS00570 0.20 -0.1 136,820 - DDA3937_RS00570 0.20 +1.4 136,820 - DDA3937_RS00570 0.20 -1.4 136,830 + DDA3937_RS00570 0.23 -2.2 136,831 - DDA3937_RS00570 0.24 -0.3 136,849 - DDA3937_RS00570 0.30 +0.2 136,849 - DDA3937_RS00570 0.30 -0.3 136,849 - DDA3937_RS00570 0.30 -0.6 136,853 + DDA3937_RS00570 0.32 +1.1 136,914 + DDA3937_RS00570 0.54 +0.5 136,915 - DDA3937_RS00570 0.55 -0.7 136,915 - DDA3937_RS00570 0.55 -0.2 136,915 - DDA3937_RS00570 0.55 -1.2 136,940 + DDA3937_RS00570 0.64 -1.7 136,941 - DDA3937_RS00570 0.64 -0.8 136,941 - DDA3937_RS00570 0.64 -1.1 137,044 + -1.8 137,044 + -0.2 137,044 + -1.0 137,045 - +1.6 137,045 - -1.2 137,045 - -1.6 137,045 - +0.8 137,046 + -0.2 137,046 + +0.7 137,046 + +0.4 137,046 + -0.3 137,046 + -3.7 137,046 + -2.8 137,046 + +0.5 137,046 + +0.3 137,046 + -1.2 137,047 - -0.9 137,047 - -1.4 137,047 - -0.9 137,047 - -1.2 137,097 + DDA3937_RS21740 0.22 +0.5 137,107 + DDA3937_RS21740 0.25 -0.8 137,107 + DDA3937_RS21740 0.25 -0.9 137,107 + DDA3937_RS21740 0.25 +2.4 137,108 - DDA3937_RS21740 0.26 -0.5 137,108 - DDA3937_RS21740 0.26 -1.7 137,110 + DDA3937_RS21740 0.26 -2.2 137,110 + DDA3937_RS21740 0.26 -1.2 137,111 - DDA3937_RS21740 0.27 -0.5 137,111 - DDA3937_RS21740 0.27 -1.5 137,111 - DDA3937_RS21740 0.27 -0.2 137,112 + DDA3937_RS21740 0.27 -0.3 137,112 + DDA3937_RS21740 0.27 -2.0 137,112 + DDA3937_RS21740 0.27 -0.3 137,113 - DDA3937_RS21740 0.27 -0.7 137,113 - DDA3937_RS21740 0.27 +0.1 137,113 - DDA3937_RS21740 0.27 -1.6 137,181 + DDA3937_RS21740 0.47 -1.1 137,181 + DDA3937_RS21740 0.47 +1.3 137,182 - DDA3937_RS21740 0.47 +0.9 137,188 + DDA3937_RS21740 0.49 +0.1 137,189 - DDA3937_RS21740 0.50 +1.6 137,189 - DDA3937_RS21740 0.50 -0.2 137,189 - DDA3937_RS21740 0.50 +1.2 137,228 - DDA3937_RS21740 0.61 -0.2 137,234 + DDA3937_RS21740 0.63 -2.7 137,234 + DDA3937_RS21740 0.63 -1.2 137,234 + DDA3937_RS21740 0.63 -1.5 137,234 + DDA3937_RS21740 0.63 -2.2 137,234 + DDA3937_RS21740 0.63 +0.3 137,235 - DDA3937_RS21740 0.63 -0.7 137,235 - DDA3937_RS21740 0.63 +0.6 137,235 - DDA3937_RS21740 0.63 +1.1 137,235 - DDA3937_RS21740 0.63 -1.8 137,235 - DDA3937_RS21740 0.63 -0.1 137,235 - DDA3937_RS21740 0.63 -1.5 137,235 - DDA3937_RS21740 0.63 -0.2 137,235 - DDA3937_RS21740 0.63 -0.7 137,235 - DDA3937_RS21740 0.63 +1.9 137,237 + DDA3937_RS21740 0.64 -1.6 137,291 + DDA3937_RS21740 0.80 -1.1 137,291 + DDA3937_RS21740 0.80 +0.9 137,314 + DDA3937_RS21740 0.86 -2.0 137,315 - DDA3937_RS21740 0.87 -0.9 137,315 - DDA3937_RS21740 0.87 -0.0 137,400 + -1.6 137,429 + -0.7 137,429 + -1.0 137,448 + -3.8 137,449 - -0.1 137,677 + DDA3937_RS00575 0.50 -1.7
Or see this region's nucleotide sequence