Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt DDA3937_RS03380 and DDA3937_RS03385 overlap by 4 nucleotides DDA3937_RS03385 and DDA3937_RS03390 overlap by 17 nucleotides DDA3937_RS03390 and DDA3937_RS03395 are separated by 74 nucleotides DDA3937_RS03395 and DDA3937_RS03400 are separated by 44 nucleotides
DDA3937_RS03380: DDA3937_RS03380 - efflux RND transporter permease subunit, at 737,744 to 740,824
_RS03380
DDA3937_RS03385: DDA3937_RS03385 - heavy metal response regulator transcription factor, at 740,821 to 741,522
_RS03385
DDA3937_RS03390: DDA3937_RS03390 - heavy metal sensor histidine kinase, at 741,506 to 742,930
_RS03390
DDA3937_RS03395: DDA3937_RS03395 - methyltransferase, at 743,005 to 743,583
_RS03395
DDA3937_RS03400: DDA3937_RS03400 - hypothetical protein, at 743,628 to 743,852
_RS03400
Position (kb) 741
742
743 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3
4 at 740.545 kb on + strand at 740.546 kb on - strand at 740.608 kb on + strand at 740.735 kb on - strand at 740.743 kb on + strand at 740.744 kb on - strand at 740.744 kb on - strand at 740.744 kb on - strand at 740.744 kb on - strand at 740.744 kb on - strand at 740.760 kb on - strand at 740.760 kb on - strand at 740.828 kb on + strand at 740.829 kb on - strand at 740.829 kb on - strand at 740.829 kb on - strand at 740.837 kb on + strand at 740.837 kb on + strand at 740.837 kb on + strand at 740.838 kb on - strand at 740.863 kb on + strand at 740.863 kb on + strand at 740.864 kb on - strand at 740.864 kb on - strand at 740.935 kb on + strand, within DDA3937_RS03385 at 740.935 kb on + strand, within DDA3937_RS03385 at 740.935 kb on + strand, within DDA3937_RS03385 at 740.936 kb on - strand, within DDA3937_RS03385 at 740.936 kb on - strand, within DDA3937_RS03385 at 740.936 kb on - strand, within DDA3937_RS03385 at 740.936 kb on - strand, within DDA3937_RS03385 at 740.936 kb on - strand, within DDA3937_RS03385 at 740.953 kb on + strand, within DDA3937_RS03385 at 740.953 kb on + strand, within DDA3937_RS03385 at 740.989 kb on - strand, within DDA3937_RS03385 at 741.071 kb on + strand, within DDA3937_RS03385 at 741.072 kb on - strand, within DDA3937_RS03385 at 741.112 kb on + strand, within DDA3937_RS03385 at 741.113 kb on - strand, within DDA3937_RS03385 at 741.113 kb on - strand, within DDA3937_RS03385 at 741.183 kb on - strand, within DDA3937_RS03385 at 741.186 kb on + strand, within DDA3937_RS03385 at 741.186 kb on + strand, within DDA3937_RS03385 at 741.186 kb on + strand, within DDA3937_RS03385 at 741.187 kb on - strand, within DDA3937_RS03385 at 741.187 kb on - strand, within DDA3937_RS03385 at 741.187 kb on - strand, within DDA3937_RS03385 at 741.187 kb on - strand, within DDA3937_RS03385 at 741.445 kb on + strand, within DDA3937_RS03385 at 741.445 kb on + strand, within DDA3937_RS03385 at 741.445 kb on + strand, within DDA3937_RS03385 at 741.446 kb on - strand, within DDA3937_RS03385 at 741.446 kb on - strand, within DDA3937_RS03385 at 741.446 kb on - strand, within DDA3937_RS03385 at 741.446 kb on - strand, within DDA3937_RS03385 at 741.521 kb on - strand at 741.581 kb on + strand at 741.581 kb on + strand at 741.582 kb on - strand at 741.602 kb on + strand at 741.602 kb on + strand at 741.602 kb on + strand at 741.602 kb on + strand at 741.602 kb on + strand at 741.603 kb on - strand at 741.603 kb on - strand at 741.626 kb on - strand at 741.655 kb on + strand, within DDA3937_RS03390 at 741.655 kb on + strand, within DDA3937_RS03390 at 741.655 kb on + strand, within DDA3937_RS03390 at 741.655 kb on + strand, within DDA3937_RS03390 at 741.656 kb on - strand, within DDA3937_RS03390 at 741.814 kb on + strand, within DDA3937_RS03390 at 741.814 kb on + strand, within DDA3937_RS03390 at 741.905 kb on + strand, within DDA3937_RS03390 at 741.906 kb on - strand, within DDA3937_RS03390 at 741.969 kb on + strand, within DDA3937_RS03390 at 741.970 kb on - strand, within DDA3937_RS03390 at 742.079 kb on - strand, within DDA3937_RS03390 at 742.123 kb on + strand, within DDA3937_RS03390 at 742.124 kb on - strand, within DDA3937_RS03390 at 742.124 kb on - strand, within DDA3937_RS03390 at 742.183 kb on + strand, within DDA3937_RS03390 at 742.184 kb on - strand, within DDA3937_RS03390 at 742.184 kb on - strand, within DDA3937_RS03390 at 742.235 kb on - strand, within DDA3937_RS03390 at 742.347 kb on - strand, within DDA3937_RS03390 at 742.347 kb on - strand, within DDA3937_RS03390 at 742.371 kb on + strand, within DDA3937_RS03390 at 742.371 kb on + strand, within DDA3937_RS03390 at 742.372 kb on - strand, within DDA3937_RS03390 at 742.372 kb on - strand, within DDA3937_RS03390 at 742.562 kb on + strand, within DDA3937_RS03390 at 742.562 kb on + strand, within DDA3937_RS03390 at 742.562 kb on + strand, within DDA3937_RS03390 at 742.562 kb on + strand, within DDA3937_RS03390 at 742.562 kb on + strand, within DDA3937_RS03390 at 742.563 kb on - strand, within DDA3937_RS03390 at 742.563 kb on - strand, within DDA3937_RS03390 at 742.563 kb on - strand, within DDA3937_RS03390 at 742.749 kb on - strand, within DDA3937_RS03390 at 742.791 kb on + strand at 742.876 kb on + strand at 742.877 kb on - strand at 742.928 kb on + strand at 742.934 kb on - strand at 742.967 kb on - strand at 742.970 kb on - strand at 742.970 kb on - strand at 742.970 kb on - strand at 742.970 kb on - strand at 742.970 kb on - strand at 743.004 kb on + strand at 743.005 kb on - strand at 743.025 kb on + strand at 743.065 kb on + strand, within DDA3937_RS03395 at 743.066 kb on - strand at 743.079 kb on + strand, within DDA3937_RS03395 at 743.100 kb on - strand, within DDA3937_RS03395 at 743.110 kb on - strand, within DDA3937_RS03395 at 743.166 kb on + strand, within DDA3937_RS03395 at 743.166 kb on + strand, within DDA3937_RS03395 at 743.218 kb on - strand, within DDA3937_RS03395 at 743.257 kb on + strand, within DDA3937_RS03395 at 743.257 kb on + strand, within DDA3937_RS03395 at 743.265 kb on + strand, within DDA3937_RS03395 at 743.266 kb on - strand, within DDA3937_RS03395 at 743.346 kb on + strand, within DDA3937_RS03395 at 743.404 kb on - strand, within DDA3937_RS03395 at 743.451 kb on + strand, within DDA3937_RS03395 at 743.470 kb on + strand, within DDA3937_RS03395 at 743.471 kb on - strand, within DDA3937_RS03395 at 743.471 kb on - strand, within DDA3937_RS03395 at 743.471 kb on - strand at 743.471 kb on - strand, within DDA3937_RS03395 at 743.472 kb on + strand, within DDA3937_RS03395 at 743.473 kb on - strand, within DDA3937_RS03395 at 743.473 kb on - strand, within DDA3937_RS03395 at 743.473 kb on - strand, within DDA3937_RS03395 at 743.492 kb on + strand, within DDA3937_RS03395 at 743.492 kb on + strand, within DDA3937_RS03395 at 743.524 kb on - strand at 743.557 kb on + strand at 743.597 kb on + strand at 743.598 kb on - strand at 743.613 kb on - strand at 743.635 kb on + strand at 743.636 kb on - strand at 743.636 kb on - strand at 743.639 kb on + strand at 743.640 kb on - strand at 743.644 kb on + strand at 743.646 kb on + strand at 743.646 kb on + strand at 743.646 kb on + strand at 743.647 kb on - strand at 743.647 kb on - strand at 743.723 kb on + strand, within DDA3937_RS03400 at 743.771 kb on - strand, within DDA3937_RS03400 at 743.771 kb on - strand, within DDA3937_RS03400 at 743.771 kb on - strand, within DDA3937_RS03400 at 743.868 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 740,545 + +1.3 740,546 - -1.7 740,608 + -1.5 740,735 - -2.0 740,743 + -0.1 740,744 - +2.2 740,744 - -0.9 740,744 - +2.2 740,744 - -1.7 740,744 - -1.5 740,760 - +0.0 740,760 - +0.3 740,828 + -0.8 740,829 - -1.1 740,829 - +0.5 740,829 - +1.5 740,837 + -2.4 740,837 + +0.8 740,837 + -0.9 740,838 - -3.0 740,863 + +4.1 740,863 + -1.3 740,864 - +0.5 740,864 - -0.8 740,935 + DDA3937_RS03385 0.16 -1.8 740,935 + DDA3937_RS03385 0.16 -1.3 740,935 + DDA3937_RS03385 0.16 -0.7 740,936 - DDA3937_RS03385 0.16 -2.4 740,936 - DDA3937_RS03385 0.16 -1.1 740,936 - DDA3937_RS03385 0.16 -1.3 740,936 - DDA3937_RS03385 0.16 +1.3 740,936 - DDA3937_RS03385 0.16 -2.0 740,953 + DDA3937_RS03385 0.19 -1.3 740,953 + DDA3937_RS03385 0.19 -1.8 740,989 - DDA3937_RS03385 0.24 -1.0 741,071 + DDA3937_RS03385 0.36 -3.5 741,072 - DDA3937_RS03385 0.36 -1.3 741,112 + DDA3937_RS03385 0.41 -2.0 741,113 - DDA3937_RS03385 0.42 -2.1 741,113 - DDA3937_RS03385 0.42 +0.3 741,183 - DDA3937_RS03385 0.52 -1.1 741,186 + DDA3937_RS03385 0.52 +0.5 741,186 + DDA3937_RS03385 0.52 -2.2 741,186 + DDA3937_RS03385 0.52 +0.5 741,187 - DDA3937_RS03385 0.52 +2.3 741,187 - DDA3937_RS03385 0.52 -0.2 741,187 - DDA3937_RS03385 0.52 -0.8 741,187 - DDA3937_RS03385 0.52 +0.2 741,445 + DDA3937_RS03385 0.89 -1.4 741,445 + DDA3937_RS03385 0.89 -0.8 741,445 + DDA3937_RS03385 0.89 -0.8 741,446 - DDA3937_RS03385 0.89 -0.3 741,446 - DDA3937_RS03385 0.89 -1.8 741,446 - DDA3937_RS03385 0.89 +1.9 741,446 - DDA3937_RS03385 0.89 -0.8 741,521 - +0.5 741,581 + +3.6 741,581 + -1.3 741,582 - -0.8 741,602 + +1.3 741,602 + -2.0 741,602 + -0.5 741,602 + -0.8 741,602 + +2.1 741,603 - -1.7 741,603 - -2.3 741,626 - +0.1 741,655 + DDA3937_RS03390 0.10 -0.8 741,655 + DDA3937_RS03390 0.10 -2.1 741,655 + DDA3937_RS03390 0.10 -1.7 741,655 + DDA3937_RS03390 0.10 -0.4 741,656 - DDA3937_RS03390 0.11 -4.0 741,814 + DDA3937_RS03390 0.22 -2.1 741,814 + DDA3937_RS03390 0.22 -1.7 741,905 + DDA3937_RS03390 0.28 -0.1 741,906 - DDA3937_RS03390 0.28 +0.1 741,969 + DDA3937_RS03390 0.32 -0.6 741,970 - DDA3937_RS03390 0.33 +0.7 742,079 - DDA3937_RS03390 0.40 -1.1 742,123 + DDA3937_RS03390 0.43 -1.0 742,124 - DDA3937_RS03390 0.43 -1.5 742,124 - DDA3937_RS03390 0.43 +0.2 742,183 + DDA3937_RS03390 0.48 +1.2 742,184 - DDA3937_RS03390 0.48 -2.2 742,184 - DDA3937_RS03390 0.48 +0.6 742,235 - DDA3937_RS03390 0.51 +2.5 742,347 - DDA3937_RS03390 0.59 -0.8 742,347 - DDA3937_RS03390 0.59 +0.8 742,371 + DDA3937_RS03390 0.61 +3.9 742,371 + DDA3937_RS03390 0.61 -2.2 742,372 - DDA3937_RS03390 0.61 -1.7 742,372 - DDA3937_RS03390 0.61 -1.2 742,562 + DDA3937_RS03390 0.74 -3.4 742,562 + DDA3937_RS03390 0.74 -0.5 742,562 + DDA3937_RS03390 0.74 +0.2 742,562 + DDA3937_RS03390 0.74 -1.3 742,562 + DDA3937_RS03390 0.74 -1.1 742,563 - DDA3937_RS03390 0.74 -2.4 742,563 - DDA3937_RS03390 0.74 -1.5 742,563 - DDA3937_RS03390 0.74 +1.9 742,749 - DDA3937_RS03390 0.87 -0.9 742,791 + -0.8 742,876 + -1.6 742,877 - -1.1 742,928 + +2.0 742,934 - +2.1 742,967 - -0.1 742,970 - -0.8 742,970 - -1.0 742,970 - +0.9 742,970 - +1.4 742,970 - -2.2 743,004 + +1.9 743,005 - +0.8 743,025 + -1.8 743,065 + DDA3937_RS03395 0.10 +0.3 743,066 - -0.5 743,079 + DDA3937_RS03395 0.13 -2.9 743,100 - DDA3937_RS03395 0.16 +0.2 743,110 - DDA3937_RS03395 0.18 +0.2 743,166 + DDA3937_RS03395 0.28 +1.5 743,166 + DDA3937_RS03395 0.28 -3.3 743,218 - DDA3937_RS03395 0.37 -0.3 743,257 + DDA3937_RS03395 0.44 -3.3 743,257 + DDA3937_RS03395 0.44 +1.5 743,265 + DDA3937_RS03395 0.45 +0.6 743,266 - DDA3937_RS03395 0.45 -0.5 743,346 + DDA3937_RS03395 0.59 -2.6 743,404 - DDA3937_RS03395 0.69 -0.2 743,451 + DDA3937_RS03395 0.77 +0.1 743,470 + DDA3937_RS03395 0.80 +0.2 743,471 - DDA3937_RS03395 0.80 +1.8 743,471 - DDA3937_RS03395 0.80 +1.6 743,471 - -1.1 743,471 - DDA3937_RS03395 0.80 -2.1 743,472 + DDA3937_RS03395 0.81 -2.3 743,473 - DDA3937_RS03395 0.81 -1.7 743,473 - DDA3937_RS03395 0.81 +0.8 743,473 - DDA3937_RS03395 0.81 +0.6 743,492 + DDA3937_RS03395 0.84 -1.7 743,492 + DDA3937_RS03395 0.84 -1.5 743,524 - +0.5 743,557 + +1.5 743,597 + +0.5 743,598 - -0.8 743,613 - -1.3 743,635 + -0.8 743,636 - -1.0 743,636 - -1.3 743,639 + -0.2 743,640 - -0.1 743,644 + +2.9 743,646 + +2.0 743,646 + +0.1 743,646 + -0.5 743,647 - -0.8 743,647 - +1.1 743,723 + DDA3937_RS03400 0.42 -1.1 743,771 - DDA3937_RS03400 0.64 +0.5 743,771 - DDA3937_RS03400 0.64 +0.8 743,771 - DDA3937_RS03400 0.64 +0.1 743,868 + -2.7
Or see this region's nucleotide sequence