Experiment: PDB
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt DDA3937_RS10270 and DDA3937_RS10275 are separated by 64 nucleotides DDA3937_RS10275 and DDA3937_RS10280 are separated by 108 nucleotides DDA3937_RS10280 and DDA3937_RS10285 are separated by 59 nucleotides
DDA3937_RS10270: DDA3937_RS10270 - peptide-methionine (R)-S-oxide reductase MsrB, at 2,316,443 to 2,316,859
_RS10270
DDA3937_RS10275: DDA3937_RS10275 - DUF1315 family protein, at 2,316,924 to 2,317,190
_RS10275
DDA3937_RS10280: DDA3937_RS10280 - bifunctional nicotinamidase/pyrazinamidase, at 2,317,299 to 2,317,940
_RS10280
DDA3937_RS10285: DDA3937_RS10285 - asparaginase, at 2,318,000 to 2,319,019
_RS10285
Position (kb)
2317
2318 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3
4 at 2316.324 kb on - strand at 2316.354 kb on + strand at 2316.354 kb on + strand at 2316.354 kb on + strand at 2316.355 kb on - strand at 2316.355 kb on - strand at 2316.355 kb on - strand at 2316.355 kb on - strand at 2316.364 kb on + strand at 2316.365 kb on - strand at 2316.365 kb on - strand at 2316.381 kb on - strand at 2316.453 kb on + strand at 2316.453 kb on + strand at 2316.454 kb on - strand at 2316.454 kb on - strand at 2316.454 kb on - strand at 2316.454 kb on - strand at 2316.483 kb on + strand at 2316.562 kb on + strand, within DDA3937_RS10270 at 2316.572 kb on + strand, within DDA3937_RS10270 at 2316.572 kb on + strand, within DDA3937_RS10270 at 2316.620 kb on + strand, within DDA3937_RS10270 at 2316.620 kb on + strand, within DDA3937_RS10270 at 2316.674 kb on - strand, within DDA3937_RS10270 at 2316.703 kb on + strand, within DDA3937_RS10270 at 2316.704 kb on - strand, within DDA3937_RS10270 at 2316.704 kb on - strand, within DDA3937_RS10270 at 2316.704 kb on - strand, within DDA3937_RS10270 at 2316.867 kb on - strand at 2316.867 kb on - strand at 2316.867 kb on - strand at 2316.869 kb on + strand at 2316.941 kb on - strand at 2316.950 kb on + strand at 2316.951 kb on - strand, within DDA3937_RS10275 at 2316.967 kb on - strand, within DDA3937_RS10275 at 2316.967 kb on - strand, within DDA3937_RS10275 at 2316.967 kb on - strand, within DDA3937_RS10275 at 2317.076 kb on + strand, within DDA3937_RS10275 at 2317.077 kb on - strand, within DDA3937_RS10275 at 2317.136 kb on + strand, within DDA3937_RS10275 at 2317.137 kb on - strand, within DDA3937_RS10275 at 2317.148 kb on - strand, within DDA3937_RS10275 at 2317.170 kb on - strand at 2317.208 kb on + strand at 2317.208 kb on + strand at 2317.209 kb on - strand at 2317.211 kb on + strand at 2317.212 kb on - strand at 2317.226 kb on + strand at 2317.226 kb on + strand at 2317.226 kb on + strand at 2317.226 kb on + strand at 2317.226 kb on + strand at 2317.227 kb on - strand at 2317.229 kb on + strand at 2317.229 kb on + strand at 2317.229 kb on + strand at 2317.230 kb on - strand at 2317.251 kb on + strand at 2317.251 kb on + strand at 2317.251 kb on + strand at 2317.251 kb on + strand at 2317.300 kb on + strand at 2317.301 kb on - strand at 2317.301 kb on - strand at 2317.468 kb on + strand, within DDA3937_RS10280 at 2317.468 kb on + strand, within DDA3937_RS10280 at 2317.469 kb on - strand, within DDA3937_RS10280 at 2317.469 kb on - strand, within DDA3937_RS10280 at 2317.469 kb on - strand, within DDA3937_RS10280 at 2317.469 kb on - strand, within DDA3937_RS10280 at 2317.469 kb on - strand, within DDA3937_RS10280 at 2317.480 kb on + strand, within DDA3937_RS10280 at 2317.540 kb on + strand, within DDA3937_RS10280 at 2317.540 kb on + strand, within DDA3937_RS10280 at 2317.540 kb on + strand, within DDA3937_RS10280 at 2317.541 kb on - strand, within DDA3937_RS10280 at 2317.541 kb on - strand, within DDA3937_RS10280 at 2317.541 kb on - strand, within DDA3937_RS10280 at 2317.583 kb on + strand, within DDA3937_RS10280 at 2317.583 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.585 kb on + strand, within DDA3937_RS10280 at 2317.586 kb on - strand, within DDA3937_RS10280 at 2317.586 kb on - strand, within DDA3937_RS10280 at 2317.586 kb on - strand, within DDA3937_RS10280 at 2317.586 kb on - strand, within DDA3937_RS10280 at 2317.586 kb on - strand, within DDA3937_RS10280 at 2317.586 kb on - strand, within DDA3937_RS10280 at 2317.617 kb on + strand, within DDA3937_RS10280 at 2317.617 kb on + strand, within DDA3937_RS10280 at 2317.617 kb on + strand, within DDA3937_RS10280 at 2317.617 kb on + strand, within DDA3937_RS10280 at 2317.617 kb on + strand, within DDA3937_RS10280 at 2317.618 kb on - strand, within DDA3937_RS10280 at 2317.621 kb on - strand, within DDA3937_RS10280 at 2317.680 kb on + strand, within DDA3937_RS10280 at 2317.680 kb on + strand, within DDA3937_RS10280 at 2317.766 kb on + strand, within DDA3937_RS10280 at 2317.766 kb on + strand, within DDA3937_RS10280 at 2317.766 kb on + strand, within DDA3937_RS10280 at 2317.767 kb on - strand, within DDA3937_RS10280 at 2317.767 kb on - strand, within DDA3937_RS10280 at 2317.767 kb on - strand, within DDA3937_RS10280 at 2317.923 kb on + strand at 2317.924 kb on - strand at 2317.940 kb on + strand at 2317.940 kb on + strand at 2317.941 kb on - strand at 2317.941 kb on - strand at 2317.957 kb on + strand at 2318.042 kb on + strand at 2318.042 kb on + strand at 2318.042 kb on + strand at 2318.043 kb on - strand at 2318.081 kb on + strand at 2318.081 kb on + strand at 2318.081 kb on + strand at 2318.088 kb on + strand at 2318.089 kb on - strand at 2318.123 kb on - strand, within DDA3937_RS10285 at 2318.172 kb on + strand, within DDA3937_RS10285 at 2318.215 kb on + strand, within DDA3937_RS10285 at 2318.295 kb on + strand, within DDA3937_RS10285 at 2318.295 kb on + strand, within DDA3937_RS10285 at 2318.296 kb on - strand, within DDA3937_RS10285 at 2318.296 kb on - strand, within DDA3937_RS10285 at 2318.555 kb on + strand, within DDA3937_RS10285 at 2318.555 kb on + strand, within DDA3937_RS10285 at 2318.555 kb on + strand, within DDA3937_RS10285 at 2318.556 kb on - strand, within DDA3937_RS10285 at 2318.610 kb on + strand, within DDA3937_RS10285 at 2318.610 kb on + strand, within DDA3937_RS10285 at 2318.611 kb on - strand, within DDA3937_RS10285 at 2318.611 kb on - strand, within DDA3937_RS10285 at 2318.784 kb on + strand, within DDA3937_RS10285 at 2318.784 kb on + strand, within DDA3937_RS10285 at 2318.784 kb on + strand, within DDA3937_RS10285 at 2318.784 kb on + strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.785 kb on - strand, within DDA3937_RS10285 at 2318.834 kb on - strand, within DDA3937_RS10285 at 2318.857 kb on + strand, within DDA3937_RS10285 at 2318.858 kb on - strand, within DDA3937_RS10285 at 2318.859 kb on + strand, within DDA3937_RS10285 at 2318.859 kb on + strand at 2318.859 kb on + strand, within DDA3937_RS10285 at 2318.859 kb on + strand, within DDA3937_RS10285 at 2318.859 kb on + strand, within DDA3937_RS10285
Per-strain Table
Position Strand Gene LocusTag Fraction PDB remove 2,316,324 - +0.5 2,316,354 + -1.9 2,316,354 + -0.7 2,316,354 + -0.6 2,316,355 - +1.0 2,316,355 - -0.6 2,316,355 - +0.8 2,316,355 - -0.6 2,316,364 + -2.3 2,316,365 - -0.7 2,316,365 - +0.2 2,316,381 - -0.1 2,316,453 + +0.4 2,316,453 + +1.3 2,316,454 - +3.3 2,316,454 - +1.3 2,316,454 - -0.4 2,316,454 - +3.8 2,316,483 + -0.6 2,316,562 + DDA3937_RS10270 0.29 +0.6 2,316,572 + DDA3937_RS10270 0.31 -0.1 2,316,572 + DDA3937_RS10270 0.31 +1.9 2,316,620 + DDA3937_RS10270 0.42 -1.9 2,316,620 + DDA3937_RS10270 0.42 +0.3 2,316,674 - DDA3937_RS10270 0.55 +2.3 2,316,703 + DDA3937_RS10270 0.62 +1.3 2,316,704 - DDA3937_RS10270 0.63 -1.4 2,316,704 - DDA3937_RS10270 0.63 +0.1 2,316,704 - DDA3937_RS10270 0.63 +1.4 2,316,867 - -0.1 2,316,867 - -0.6 2,316,867 - -1.7 2,316,869 + +0.3 2,316,941 - +1.0 2,316,950 + +0.7 2,316,951 - DDA3937_RS10275 0.10 -0.6 2,316,967 - DDA3937_RS10275 0.16 +1.4 2,316,967 - DDA3937_RS10275 0.16 +1.7 2,316,967 - DDA3937_RS10275 0.16 -1.6 2,317,076 + DDA3937_RS10275 0.57 +0.5 2,317,077 - DDA3937_RS10275 0.57 -1.4 2,317,136 + DDA3937_RS10275 0.79 +0.1 2,317,137 - DDA3937_RS10275 0.80 -1.2 2,317,148 - DDA3937_RS10275 0.84 -0.2 2,317,170 - +1.4 2,317,208 + -0.6 2,317,208 + +1.8 2,317,209 - +3.6 2,317,211 + -0.6 2,317,212 - -2.0 2,317,226 + -1.9 2,317,226 + +1.4 2,317,226 + +0.3 2,317,226 + -2.8 2,317,226 + +1.3 2,317,227 - -0.9 2,317,229 + +0.6 2,317,229 + -0.8 2,317,229 + -1.7 2,317,230 - +1.8 2,317,251 + -0.3 2,317,251 + -0.9 2,317,251 + -1.1 2,317,251 + -0.0 2,317,300 + +1.2 2,317,301 - -0.2 2,317,301 - -0.4 2,317,468 + DDA3937_RS10280 0.26 -1.4 2,317,468 + DDA3937_RS10280 0.26 -3.2 2,317,469 - DDA3937_RS10280 0.26 -2.1 2,317,469 - DDA3937_RS10280 0.26 +0.5 2,317,469 - DDA3937_RS10280 0.26 -1.9 2,317,469 - DDA3937_RS10280 0.26 +0.4 2,317,469 - DDA3937_RS10280 0.26 -2.4 2,317,480 + DDA3937_RS10280 0.28 -1.7 2,317,540 + DDA3937_RS10280 0.38 -0.6 2,317,540 + DDA3937_RS10280 0.38 -1.5 2,317,540 + DDA3937_RS10280 0.38 -0.1 2,317,541 - DDA3937_RS10280 0.38 +0.9 2,317,541 - DDA3937_RS10280 0.38 +2.0 2,317,541 - DDA3937_RS10280 0.38 -1.1 2,317,583 + DDA3937_RS10280 0.44 +0.1 2,317,583 + DDA3937_RS10280 0.44 -0.1 2,317,585 + DDA3937_RS10280 0.45 -1.7 2,317,585 + DDA3937_RS10280 0.45 -0.6 2,317,585 + DDA3937_RS10280 0.45 -3.5 2,317,585 + DDA3937_RS10280 0.45 -0.6 2,317,585 + DDA3937_RS10280 0.45 -0.6 2,317,585 + DDA3937_RS10280 0.45 -0.3 2,317,585 + DDA3937_RS10280 0.45 -2.6 2,317,585 + DDA3937_RS10280 0.45 +0.0 2,317,585 + DDA3937_RS10280 0.45 +0.4 2,317,586 - DDA3937_RS10280 0.45 -0.1 2,317,586 - DDA3937_RS10280 0.45 -0.6 2,317,586 - DDA3937_RS10280 0.45 -0.0 2,317,586 - DDA3937_RS10280 0.45 +0.4 2,317,586 - DDA3937_RS10280 0.45 +0.4 2,317,586 - DDA3937_RS10280 0.45 +0.8 2,317,617 + DDA3937_RS10280 0.50 +2.0 2,317,617 + DDA3937_RS10280 0.50 +1.1 2,317,617 + DDA3937_RS10280 0.50 +0.2 2,317,617 + DDA3937_RS10280 0.50 +0.4 2,317,617 + DDA3937_RS10280 0.50 +0.8 2,317,618 - DDA3937_RS10280 0.50 -2.7 2,317,621 - DDA3937_RS10280 0.50 -0.9 2,317,680 + DDA3937_RS10280 0.59 -0.1 2,317,680 + DDA3937_RS10280 0.59 -1.5 2,317,766 + DDA3937_RS10280 0.73 +0.0 2,317,766 + DDA3937_RS10280 0.73 +0.1 2,317,766 + DDA3937_RS10280 0.73 -1.9 2,317,767 - DDA3937_RS10280 0.73 -0.1 2,317,767 - DDA3937_RS10280 0.73 -2.1 2,317,767 - DDA3937_RS10280 0.73 -2.5 2,317,923 + +0.9 2,317,924 - -2.0 2,317,940 + -0.1 2,317,940 + -0.3 2,317,941 - +0.3 2,317,941 - +3.6 2,317,957 + -0.1 2,318,042 + -2.1 2,318,042 + -0.6 2,318,042 + +0.0 2,318,043 - +1.4 2,318,081 + -0.0 2,318,081 + -1.1 2,318,081 + -1.7 2,318,088 + -1.1 2,318,089 - +2.0 2,318,123 - DDA3937_RS10285 0.12 -0.6 2,318,172 + DDA3937_RS10285 0.17 -0.1 2,318,215 + DDA3937_RS10285 0.21 +1.4 2,318,295 + DDA3937_RS10285 0.29 -0.6 2,318,295 + DDA3937_RS10285 0.29 -1.6 2,318,296 - DDA3937_RS10285 0.29 +1.1 2,318,296 - DDA3937_RS10285 0.29 +1.4 2,318,555 + DDA3937_RS10285 0.54 +0.5 2,318,555 + DDA3937_RS10285 0.54 -0.9 2,318,555 + DDA3937_RS10285 0.54 -1.1 2,318,556 - DDA3937_RS10285 0.55 +1.6 2,318,610 + DDA3937_RS10285 0.60 -0.5 2,318,610 + DDA3937_RS10285 0.60 +0.4 2,318,611 - DDA3937_RS10285 0.60 -2.0 2,318,611 - DDA3937_RS10285 0.60 -1.6 2,318,784 + DDA3937_RS10285 0.77 +0.5 2,318,784 + DDA3937_RS10285 0.77 -0.7 2,318,784 + DDA3937_RS10285 0.77 +0.7 2,318,784 + DDA3937_RS10285 0.77 +2.3 2,318,785 - DDA3937_RS10285 0.77 -0.3 2,318,785 - DDA3937_RS10285 0.77 +0.1 2,318,785 - DDA3937_RS10285 0.77 +2.3 2,318,785 - DDA3937_RS10285 0.77 +0.7 2,318,785 - DDA3937_RS10285 0.77 +0.3 2,318,785 - DDA3937_RS10285 0.77 -1.4 2,318,785 - DDA3937_RS10285 0.77 -1.1 2,318,834 - DDA3937_RS10285 0.82 +0.4 2,318,857 + DDA3937_RS10285 0.84 +2.0 2,318,858 - DDA3937_RS10285 0.84 -0.1 2,318,859 + DDA3937_RS10285 0.84 -0.9 2,318,859 + +1.4 2,318,859 + DDA3937_RS10285 0.84 +0.4 2,318,859 + DDA3937_RS10285 0.84 +0.4 2,318,859 + DDA3937_RS10285 0.84 +0.1
Or see this region's nucleotide sequence