Experiment: SMSA with Ralstonia_antibiotic_mix_minus_Polymyxin_and_Chloramphenicol
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt RPSI07_RS16095 and RPSI07_RS16100 are separated by 78 nucleotides RPSI07_RS16100 and RPSI07_RS16105 are separated by 103 nucleotides RPSI07_RS16105 and RPSI07_RS16110 are separated by 131 nucleotides RPSI07_RS16110 and RPSI07_RS25105 are separated by 93 nucleotides RPSI07_RS25105 and RPSI07_RS16115 overlap by 37 nucleotides
RPSI07_RS16095: RPSI07_RS16095 - efflux RND transporter periplasmic adaptor subunit, at 1,767,065 to 1,768,273
_RS16095
RPSI07_RS16100: RPSI07_RS16100 - AcrB/AcrD/AcrF family protein, at 1,768,352 to 1,771,471
_RS16100
RPSI07_RS16105: RPSI07_RS16105 - tRNA-Leu, at 1,771,575 to 1,771,661
_RS16105
RPSI07_RS16110: RPSI07_RS16110 - hypothetical protein, at 1,771,793 to 1,771,987
_RS16110
RPSI07_RS25105: RPSI07_RS25105 - hypothetical protein, at 1,772,081 to 1,772,410
_RS25105
RPSI07_RS16115: RPSI07_RS16115 - bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC, at 1,772,374 to 1,774,380
_RS16115
Position (kb)
1768
1769
1770
1771
1772 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 1767.569 kb on + strand, within RPSI07_RS16095 at 1767.570 kb on - strand, within RPSI07_RS16095 at 1767.638 kb on + strand, within RPSI07_RS16095 at 1767.639 kb on - strand, within RPSI07_RS16095 at 1767.858 kb on + strand, within RPSI07_RS16095 at 1768.056 kb on + strand, within RPSI07_RS16095 at 1768.067 kb on + strand, within RPSI07_RS16095 at 1768.067 kb on + strand, within RPSI07_RS16095 at 1768.068 kb on - strand, within RPSI07_RS16095 at 1768.452 kb on - strand at 1768.453 kb on + strand at 1768.592 kb on + strand at 1768.614 kb on - strand at 1768.692 kb on - strand, within RPSI07_RS16100 at 1768.692 kb on - strand, within RPSI07_RS16100 at 1768.754 kb on + strand, within RPSI07_RS16100 at 1768.755 kb on - strand at 1768.793 kb on + strand, within RPSI07_RS16100 at 1768.794 kb on - strand, within RPSI07_RS16100 at 1768.821 kb on - strand, within RPSI07_RS16100 at 1768.922 kb on + strand at 1768.922 kb on + strand, within RPSI07_RS16100 at 1768.923 kb on - strand, within RPSI07_RS16100 at 1769.129 kb on - strand, within RPSI07_RS16100 at 1769.681 kb on + strand, within RPSI07_RS16100 at 1769.682 kb on - strand, within RPSI07_RS16100 at 1769.682 kb on - strand, within RPSI07_RS16100 at 1769.774 kb on + strand, within RPSI07_RS16100 at 1769.817 kb on + strand, within RPSI07_RS16100 at 1769.850 kb on - strand, within RPSI07_RS16100 at 1769.967 kb on - strand, within RPSI07_RS16100 at 1770.029 kb on + strand, within RPSI07_RS16100 at 1770.029 kb on + strand, within RPSI07_RS16100 at 1771.412 kb on + strand at 1771.413 kb on - strand at 1771.766 kb on + strand at 1771.860 kb on + strand, within RPSI07_RS16110 at 1771.860 kb on + strand, within RPSI07_RS16110 at 1771.964 kb on + strand, within RPSI07_RS16110 at 1771.986 kb on - strand at 1772.199 kb on + strand, within RPSI07_RS25105 at 1772.216 kb on + strand, within RPSI07_RS25105 at 1772.216 kb on + strand, within RPSI07_RS25105 at 1772.217 kb on - strand, within RPSI07_RS25105 at 1772.453 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction SMSA with Ralstonia_antibiotic_mix_minus_Polymyxin_and_Chloramphenicol remove 1,767,569 + RPSI07_RS16095 0.42 -1.2 1,767,570 - RPSI07_RS16095 0.42 -1.2 1,767,638 + RPSI07_RS16095 0.47 -1.2 1,767,639 - RPSI07_RS16095 0.47 +1.8 1,767,858 + RPSI07_RS16095 0.66 +0.8 1,768,056 + RPSI07_RS16095 0.82 -0.2 1,768,067 + RPSI07_RS16095 0.83 -0.2 1,768,067 + RPSI07_RS16095 0.83 +0.8 1,768,068 - RPSI07_RS16095 0.83 -0.5 1,768,452 - +0.8 1,768,453 + -1.2 1,768,592 + -0.8 1,768,614 - +0.8 1,768,692 - RPSI07_RS16100 0.11 -0.2 1,768,692 - RPSI07_RS16100 0.11 +0.8 1,768,754 + RPSI07_RS16100 0.13 -0.2 1,768,755 - -0.2 1,768,793 + RPSI07_RS16100 0.14 +0.4 1,768,794 - RPSI07_RS16100 0.14 -1.2 1,768,821 - RPSI07_RS16100 0.15 -0.2 1,768,922 + +0.8 1,768,922 + RPSI07_RS16100 0.18 +0.8 1,768,923 - RPSI07_RS16100 0.18 -0.2 1,769,129 - RPSI07_RS16100 0.25 +0.8 1,769,681 + RPSI07_RS16100 0.43 -0.2 1,769,682 - RPSI07_RS16100 0.43 -1.2 1,769,682 - RPSI07_RS16100 0.43 -1.8 1,769,774 + RPSI07_RS16100 0.46 -0.1 1,769,817 + RPSI07_RS16100 0.47 +0.8 1,769,850 - RPSI07_RS16100 0.48 -0.2 1,769,967 - RPSI07_RS16100 0.52 -2.0 1,770,029 + RPSI07_RS16100 0.54 -0.8 1,770,029 + RPSI07_RS16100 0.54 -0.2 1,771,412 + -1.4 1,771,413 - -0.8 1,771,766 + -0.2 1,771,860 + RPSI07_RS16110 0.34 -0.1 1,771,860 + RPSI07_RS16110 0.34 +1.0 1,771,964 + RPSI07_RS16110 0.88 +0.8 1,771,986 - -0.2 1,772,199 + RPSI07_RS25105 0.36 +0.9 1,772,216 + RPSI07_RS25105 0.41 -0.4 1,772,216 + RPSI07_RS25105 0.41 -1.4 1,772,217 - RPSI07_RS25105 0.41 +0.8 1,772,453 - +0.8
Or see this region's nucleotide sequence