Strain Fitness in Escherichia coli BW25113 around b2126

Experiment: 2,4-Dinitrophenol 2 mM

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntyehS and yehT are separated by 46 nucleotidesyehT and yehU overlap by 4 nucleotidesyehU and mlrA are separated by 221 nucleotides b2124: yehS - hypothetical protein (NCBI), at 2,209,748 to 2,210,218 yehS b2125: yehT - orf, hypothetical protein (VIMSS), at 2,210,265 to 2,210,984 yehT b2126: yehU - predicted sensory kinase in two-component system with YehT (NCBI), at 2,210,981 to 2,212,666 yehU b2127: mlrA - DNA-binding transcriptional regulator (NCBI), at 2,212,888 to 2,213,619 mlrA Position (kb) 2210 2211 2212 2213Strain fitness (log2 ratio) -1 0 1 2at 2210.041 kb on - strand, within yehSat 2210.106 kb on - strand, within yehSat 2210.106 kb on - strand, within yehSat 2210.138 kb on - strand, within yehSat 2210.161 kb on + strand, within yehSat 2210.185 kb on + strandat 2210.193 kb on - strandat 2210.203 kb on - strandat 2210.313 kb on - strandat 2210.408 kb on - strand, within yehTat 2210.411 kb on - strand, within yehTat 2210.492 kb on + strand, within yehTat 2210.492 kb on + strand, within yehTat 2210.498 kb on - strand, within yehTat 2210.502 kb on + strand, within yehTat 2210.695 kb on - strand, within yehTat 2210.695 kb on - strand, within yehTat 2210.715 kb on + strand, within yehTat 2210.715 kb on + strand, within yehTat 2210.858 kb on - strand, within yehTat 2210.858 kb on - strand, within yehTat 2210.936 kb on + strandat 2210.954 kb on - strandat 2210.962 kb on - strandat 2210.962 kb on - strandat 2211.049 kb on - strandat 2211.051 kb on + strandat 2211.130 kb on - strandat 2211.130 kb on - strandat 2211.207 kb on - strand, within yehUat 2211.207 kb on - strand, within yehUat 2211.218 kb on - strand, within yehUat 2211.273 kb on - strand, within yehUat 2211.273 kb on - strand, within yehUat 2211.371 kb on - strand, within yehUat 2211.399 kb on - strand, within yehUat 2211.451 kb on - strand, within yehUat 2211.464 kb on - strand, within yehUat 2211.539 kb on - strand, within yehUat 2211.539 kb on - strand, within yehUat 2211.651 kb on + strand, within yehUat 2211.675 kb on + strand, within yehUat 2211.688 kb on - strand, within yehUat 2211.688 kb on - strand, within yehUat 2211.782 kb on - strand, within yehUat 2211.806 kb on - strand, within yehUat 2211.826 kb on + strand, within yehUat 2211.834 kb on - strand, within yehUat 2211.961 kb on - strand, within yehUat 2211.972 kb on - strand, within yehUat 2211.972 kb on - strand, within yehUat 2212.028 kb on + strand, within yehUat 2212.168 kb on + strand, within yehUat 2212.177 kb on - strand, within yehUat 2212.177 kb on - strand, within yehUat 2212.256 kb on - strand, within yehUat 2212.264 kb on - strand, within yehUat 2212.294 kb on + strand, within yehUat 2212.358 kb on - strand, within yehUat 2212.358 kb on - strand, within yehUat 2212.365 kb on + strand, within yehUat 2212.373 kb on - strand, within yehUat 2212.438 kb on - strand, within yehUat 2212.438 kb on - strand, within yehUat 2212.564 kb on + strandat 2213.000 kb on + strand, within mlrAat 2213.008 kb on - strand, within mlrAat 2213.008 kb on - strand, within mlrAat 2213.066 kb on - strand, within mlrAat 2213.222 kb on - strand, within mlrAat 2213.244 kb on + strand, within mlrAat 2213.370 kb on + strand, within mlrAat 2213.370 kb on + strand, within mlrAat 2213.444 kb on + strand, within mlrAat 2213.484 kb on + strand, within mlrAat 2213.506 kb on + strand, within mlrAat 2213.506 kb on + strand, within mlrAat 2213.513 kb on + strand, within mlrAat 2213.641 kb on + strandat 2213.641 kb on + strandat 2213.646 kb on + strandat 2213.654 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 2,4-Dinitrophenol 2 mM
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2,210,041 - yehS b2124 0.62 -0.3
2,210,106 - yehS b2124 0.76 +0.1
2,210,106 - yehS b2124 0.76 +0.6
2,210,138 - yehS b2124 0.83 -0.1
2,210,161 + yehS b2124 0.88 +0.3
2,210,185 + -0.8
2,210,193 - -0.1
2,210,203 - -0.2
2,210,313 - -0.5
2,210,408 - yehT b2125 0.20 +0.4
2,210,411 - yehT b2125 0.20 +0.9
2,210,492 + yehT b2125 0.32 +0.8
2,210,492 + yehT b2125 0.32 +1.1
2,210,498 - yehT b2125 0.32 -0.0
2,210,502 + yehT b2125 0.33 +1.3
2,210,695 - yehT b2125 0.60 +0.8
2,210,695 - yehT b2125 0.60 +1.1
2,210,715 + yehT b2125 0.62 +0.2
2,210,715 + yehT b2125 0.62 +0.1
2,210,858 - yehT b2125 0.82 +0.5
2,210,858 - yehT b2125 0.82 -0.3
2,210,936 + +0.4
2,210,954 - +2.0
2,210,962 - -0.9
2,210,962 - +1.3
2,211,049 - +0.4
2,211,051 + +0.6
2,211,130 - -0.5
2,211,130 - +1.1
2,211,207 - yehU b2126 0.13 -0.3
2,211,207 - yehU b2126 0.13 +0.2
2,211,218 - yehU b2126 0.14 +0.7
2,211,273 - yehU b2126 0.17 -0.3
2,211,273 - yehU b2126 0.17 +1.0
2,211,371 - yehU b2126 0.23 +0.8
2,211,399 - yehU b2126 0.25 +0.6
2,211,451 - yehU b2126 0.28 +0.4
2,211,464 - yehU b2126 0.29 +0.9
2,211,539 - yehU b2126 0.33 +1.0
2,211,539 - yehU b2126 0.33 +1.2
2,211,651 + yehU b2126 0.40 -0.1
2,211,675 + yehU b2126 0.41 +0.6
2,211,688 - yehU b2126 0.42 +0.9
2,211,688 - yehU b2126 0.42 +0.8
2,211,782 - yehU b2126 0.48 +0.2
2,211,806 - yehU b2126 0.49 -0.1
2,211,826 + yehU b2126 0.50 +0.7
2,211,834 - yehU b2126 0.51 +0.6
2,211,961 - yehU b2126 0.58 +0.1
2,211,972 - yehU b2126 0.59 +1.0
2,211,972 - yehU b2126 0.59 +1.0
2,212,028 + yehU b2126 0.62 +0.8
2,212,168 + yehU b2126 0.70 +1.5
2,212,177 - yehU b2126 0.71 +0.4
2,212,177 - yehU b2126 0.71 +1.2
2,212,256 - yehU b2126 0.76 +0.6
2,212,264 - yehU b2126 0.76 -1.1
2,212,294 + yehU b2126 0.78 +0.6
2,212,358 - yehU b2126 0.82 -0.2
2,212,358 - yehU b2126 0.82 -0.0
2,212,365 + yehU b2126 0.82 +0.2
2,212,373 - yehU b2126 0.83 +0.2
2,212,438 - yehU b2126 0.86 +0.3
2,212,438 - yehU b2126 0.86 +0.7
2,212,564 + +1.3
2,213,000 + mlrA b2127 0.15 +0.3
2,213,008 - mlrA b2127 0.16 -0.8
2,213,008 - mlrA b2127 0.16 +0.8
2,213,066 - mlrA b2127 0.24 -0.4
2,213,222 - mlrA b2127 0.46 +0.9
2,213,244 + mlrA b2127 0.49 +0.3
2,213,370 + mlrA b2127 0.66 +0.5
2,213,370 + mlrA b2127 0.66 +0.9
2,213,444 + mlrA b2127 0.76 -0.1
2,213,484 + mlrA b2127 0.81 -0.3
2,213,506 + mlrA b2127 0.84 +0.4
2,213,506 + mlrA b2127 0.84 +0.6
2,213,513 + mlrA b2127 0.85 -0.5
2,213,641 + +1.5
2,213,641 + -0.8
2,213,646 + +0.3
2,213,654 - -0.7

Or see this region's nucleotide sequence