Strain Fitness in Escherichia coli ECOR38 around HEPCGN_18115

Experiment: Bas61

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntkpsT and neuD are separated by 49 nucleotidesneuD and neuB overlap by 4 nucleotidesneuB and neuA overlap by 1 nucleotides HEPCGN_18105: kpsT - Polysialic acid transport ATP-binding protein, at 2,370,224 to 2,370,883 kpsT HEPCGN_18110: neuD - NeuD protein involved in sialic acid synthesis, at 2,370,933 to 2,371,556 neuD HEPCGN_18115: neuB - N-acylneuraminate-9-phosphate synthase, at 2,371,553 to 2,372,593 neuB HEPCGN_18120: neuA - N-acylneuraminate cytidylyltransferase, at 2,372,593 to 2,373,849 neuA Position (kb) 2371 2372 2373Strain fitness (log2 ratio) -1 0 1at 2371.265 kb on + strand, within neuDat 2371.367 kb on + strand, within neuDat 2371.425 kb on - strand, within neuDat 2371.506 kb on - strandat 2371.563 kb on + strandat 2371.565 kb on + strandat 2371.784 kb on + strand, within neuBat 2372.509 kb on + strandat 2372.592 kb on - strandat 2372.692 kb on + strandat 2372.782 kb on + strand, within neuAat 2372.782 kb on + strand, within neuAat 2372.869 kb on + strand, within neuA

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Per-strain Table

Position Strand Gene LocusTag Fraction Bas61
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2,371,265 + neuD HEPCGN_18110 0.53 -0.2
2,371,367 + neuD HEPCGN_18110 0.70 +0.1
2,371,425 - neuD HEPCGN_18110 0.79 +0.1
2,371,506 - -0.3
2,371,563 + +0.3
2,371,565 + -1.1
2,371,784 + neuB HEPCGN_18115 0.22 -0.9
2,372,509 + +0.2
2,372,592 - -0.3
2,372,692 + -1.0
2,372,782 + neuA HEPCGN_18120 0.15 -0.7
2,372,782 + neuA HEPCGN_18120 0.15 -1.2
2,372,869 + neuA HEPCGN_18120 0.22 -1.1

Or see this region's nucleotide sequence